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Abstract:

The antiviral effect of polysaccharides has been known for many years. Carrageenans are considered a good alternative for the prevention of a wide range of diseases, mainly caused by enveloped viruses. The advantages lie on their high availability, low cost and low induction of resistance. The aim of this study was to evaluate the sensitivity of two viral pathogens of veterinary interest to the presence of lambda-carrageenan. This is the first report of a lambda-carrageenan having antiviral activity against animal viruses belonging to the Alphaherpesvirinae subfamily, BoHV-1 (bovine herpesvirus type 1) strain Cooper and SuHV-1 (suid herpesvirus type 1) strain Bartha. Lambda-carrageenan was able to reduce infectivity of both viruses with a more pronounced effect against BoHV-1. These results proved, as previously shown for human herpes virus type 1, that these compounds could be used as potential antiviral agents in the veterinary field. © 2014 Elsevier Ltd.

Registro:

Documento: Artículo
Título:Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1
Autor:Diogo, J.V.; Novo, S.G.; González, M.J.; Ciancia, M.; Bratanich, A.C.
Filiación:Área de Virología, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires, Av. Chorroarín 280, Buenos Aires, C1427CWO, Argentina
Cátedra de Química de Biomoléculas, Departamento de Biología Aplicada y Alimentos, Facultad de Agronomía, Universidad de Buenos Aires, Av. San Martín 4453, Buenos Aires, C1417DSE, Argentina
National Research Council of Argentina (CIHIDECAR-CONICET), Ciudad Universitaria, Pabellón 2, Buenos Aires, C1428EHA, Argentina
Palabras clave:Antiviral; Herpesvirus; Lambda-carrageenan; carrageenan; lambda carrageenan; unclassified drug; antivirus agent; carrageenan; Alphaherpesvirinae; animal cell; antiviral activity; Article; Bovine herpesvirus 1; concentration response; controlled study; drug mechanism; Gigartina skottsbergii; nonhuman; seaweed; suid herpesvirus type 1; virus infectivity; virus strain; animal; chemistry; dog; drug effects; MDCK cell line; Pseudorabies virus; red alga; Alphaherpesvirinae; Animalia; Bovine herpesvirus 1; Gigartina skottsbergii; Herpesviridae; Human herpesvirus 1; Simplexvirus; Suid herpesvirus 1; Animals; Antiviral Agents; Carrageenan; Dogs; Herpesvirus 1, Bovine; Herpesvirus 1, Suid; Madin Darby Canine Kidney Cells; Rhodophyta
Año:2015
Volumen:98
Página de inicio:142
Página de fin:144
DOI: http://dx.doi.org/10.1016/j.rvsc.2014.11.010
Título revista:Research in Veterinary Science
Título revista abreviado:Res. Vet. Sci.
ISSN:00345288
CODEN:RVTSA
CAS:carrageenan, 9000-07-1, 9049-05-2, 9061-82-9, 9064-57-7; Antiviral Agents; Carrageenan
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00345288_v98_n_p142_Diogo

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Citas:

---------- APA ----------
Diogo, J.V., Novo, S.G., González, M.J., Ciancia, M. & Bratanich, A.C. (2015) . Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1. Research in Veterinary Science, 98, 142-144.
http://dx.doi.org/10.1016/j.rvsc.2014.11.010
---------- CHICAGO ----------
Diogo, J.V., Novo, S.G., González, M.J., Ciancia, M., Bratanich, A.C. "Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1" . Research in Veterinary Science 98 (2015) : 142-144.
http://dx.doi.org/10.1016/j.rvsc.2014.11.010
---------- MLA ----------
Diogo, J.V., Novo, S.G., González, M.J., Ciancia, M., Bratanich, A.C. "Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1" . Research in Veterinary Science, vol. 98, 2015, pp. 142-144.
http://dx.doi.org/10.1016/j.rvsc.2014.11.010
---------- VANCOUVER ----------
Diogo, J.V., Novo, S.G., González, M.J., Ciancia, M., Bratanich, A.C. Antiviral activity of lambda-carrageenan prepared from red seaweed (Gigartina skottsbergii) against BoHV-1 and SuHV-1. Res. Vet. Sci. 2015;98:142-144.
http://dx.doi.org/10.1016/j.rvsc.2014.11.010