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Fernández, L.R.; Cirigliano, A.; Fabani, M.P.; Lima, B.; Alberti, S.; Kramer, F.; Tapia, A.A.; Cabrera, G.; Palermo, J.A.; Sánchez, M. "Antioxidant neolignans from Cordia americana" (2013) Planta Medica. 79(18):1724-1729
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Abstract:

Five new neolignans with a bicyclo[2.2.2]octene framework were isolated from an ethanolic extract of the bark of Cordia americana. The structures and relative configurations of the compounds were elucidated by a combination of spectroscopic methods. All the isolated compounds showed good antioxidant activities in the DPPH radical scavenging (0.5-100 μg/mL) and Ferric-reducing antioxidant power (FRAP, 1-100 μg/mL) assays. One of the compounds displayed mild fungistatic activity at 0.1 μmol/spot against Fusarium virguliforme while, at the same time, all compounds were inactive against several strains of Gram (+) and Gram (-) bacteria at all assayed concentrations (10-1000 μg/mL). © Georg Thieme Verlag KG Stuttgart · New York.

Registro:

Documento: Artículo
Título:Antioxidant neolignans from Cordia americana
Autor:Fernández, L.R.; Cirigliano, A.; Fabani, M.P.; Lima, B.; Alberti, S.; Kramer, F.; Tapia, A.A.; Cabrera, G.; Palermo, J.A.; Sánchez, M.
Filiación:UMYMFOR, Departamento de Química Orgánica, Universidad de Buenos Aires, 1428 Buenos Aires, Argentina
Instituto de Biotecnologia - Catedras Bioquimica Agricola y Quimica Organica, Departamento de Ingeniería Agronómica, Universidad Nacional de San Juan, San Juan, Argentina
Departamento de Farmacia, Facultad de Ciencias Exactas, Químicas y Naturales, Universidad Nacional de Misiones, Posadas, Argentina
Palabras clave:antioxidant activity; bicyclo[2.2.2]octene; Boraginaceae; Cordia americana; neolignans; rufescenolides; yunnaneic acids; 1,1 diphenyl 2 picrylhydrazyl; alcohol; benomyl; cefotaxime; neolignan; rufescenolide B; rufescenolide C; rufescenolide D; unclassified drug; yunnaneic acid I; yunnaneic acid J; antifungal activity; antimicrobial activity; antioxidant activity; antioxidant assay; article; bacterial strain; bark; carbon nuclear magnetic resonance; controlled study; Cordia; Cordia americana; DPPH radical scavenging assay; drug isolation; drug structure; Escherichia coli; Fusarium; Fusarium virguliforme; heteronuclear multiple bond correlation; nonhuman; proton nuclear magnetic resonance; Pseudomonas aeruginosa; Salmonella; Salmonella enteritidis; Staphylococcus aureus; structure analysis; Yersinia enterocolitica; Boraginaceae; Cordia; Fusarium virguliforme; Antifungal Agents; Antioxidants; Bacteria; Bicyclo Compounds; Cordia; Free Radical Scavengers; Fusarium; Lignans; Medicine, Traditional; Molecular Structure; Oxidation-Reduction; Plant Bark; Plant Extracts; Plants, Medicinal
Año:2013
Volumen:79
Número:18
Página de inicio:1724
Página de fin:1729
DOI: http://dx.doi.org/10.1055/s-0033-1351052
Título revista:Planta Medica
Título revista abreviado:Planta Med.
ISSN:00320943
CODEN:PLMEA
CAS:1,1 diphenyl 2 picrylhydrazyl, 1898-66-4; alcohol, 64-17-5; benomyl, 17804-35-2; cefotaxime, 63527-52-6, 64485-93-4
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00320943_v79_n18_p1724_Fernandez

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Citas:

---------- APA ----------
Fernández, L.R., Cirigliano, A., Fabani, M.P., Lima, B., Alberti, S., Kramer, F., Tapia, A.A.,..., Sánchez, M. (2013) . Antioxidant neolignans from Cordia americana. Planta Medica, 79(18), 1724-1729.
http://dx.doi.org/10.1055/s-0033-1351052
---------- CHICAGO ----------
Fernández, L.R., Cirigliano, A., Fabani, M.P., Lima, B., Alberti, S., Kramer, F., et al. "Antioxidant neolignans from Cordia americana" . Planta Medica 79, no. 18 (2013) : 1724-1729.
http://dx.doi.org/10.1055/s-0033-1351052
---------- MLA ----------
Fernández, L.R., Cirigliano, A., Fabani, M.P., Lima, B., Alberti, S., Kramer, F., et al. "Antioxidant neolignans from Cordia americana" . Planta Medica, vol. 79, no. 18, 2013, pp. 1724-1729.
http://dx.doi.org/10.1055/s-0033-1351052
---------- VANCOUVER ----------
Fernández, L.R., Cirigliano, A., Fabani, M.P., Lima, B., Alberti, S., Kramer, F., et al. Antioxidant neolignans from Cordia americana. Planta Med. 2013;79(18):1724-1729.
http://dx.doi.org/10.1055/s-0033-1351052