To excised leaves and 15-day-old seedlings of Acnistus breviflorus sodium [1-14C]acetate, [2-14C]mevalonolactone and [14C-methyl]methionine were administered in separate experiments. From the absolute incorporation values of withaferin A (1), jaborosalactone A (2) and jaborosalactone D (3) isolated at different times after administration of the tracers, it was deduced that compound 2 is a precursor of both 1 and 3 and that the withanolides are later biodegraded to unknown products. Inoculation of [14C]jaborosalactone A confirmed its transformation into 1 and 3. © 1985.
Documento: | Artículo |
Título: | Biosynthesis of withanolides in Acnistus breviflorus: biogenetic relationships among the main withanolides |
Autor: | Veleiro, A.S.; Burton, G.; Gros, E.G. |
Filiación: | Departamento de Química Orgánica, UMYMFOR, Facultad de Ciencias Exactas y Naturales, Pabellon 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina |
Palabras clave: | Acnistus breviflorus; biosynthesis.; Solanaceae; withanolide |
Año: | 1985 |
Volumen: | 24 |
Número: | 11 |
Página de inicio: | 2573 |
Página de fin: | 2575 |
DOI: | http://dx.doi.org/10.1016/S0031-9422(00)80671-8 |
Título revista: | Phytochemistry |
Título revista abreviado: | Phytochemistry |
ISSN: | 00319422 |
CODEN: | PYTCA |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v24_n11_p2573_Veleiro |