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Abstract:

Changes of the stinging response threshold of Apis mellifera a scutellata were measured on foragers fixed on a holder and stimulated with an electric shock as a noxious stimulus. The threshold of responsiveness to the noxious stimulus increased when bees were previously stimulated with isopentyl acetate, which is a main component of the alarm pheromone of the sting chamber. This effect is antagonised by previous injection of naloxone-hydrochloride (Endo Laboratories Inc.). Results suggest that in the honeybee an endogenous opioid system activated by isopentyl acetate is responsible for modulation of perception for nociceptive stimuli. The resulting stress-induced analgesia in the defender bee would reduce its probability of withdrawal thus increasing its efficiency against enemies.

Registro:

Documento: Artículo
Título:Alarm pheromone induces stress analgesia via an opioid system in the honeybee
Autor:Núñez, J.; Almeida, L.; Balderrama, N.; Giurfa, M.
Filiación:Laboratory of Insect Physiology, Dept. Biol. Sci., FCEyN, Univ. B., Buenos Aires, Argentina
Instituto Zoologia Agricola, Facultad Agronomía, Universidad Central de Venezuela, Aptdo. Postal 4579, Maracay 2101, Aragua, Venezuela
Institut für Neurobiologie, Freie Universität Berlin, Königin-Luise-Str. 28/30, 14195 Berlin, Germany
Palabras clave:Alarm pheromone; Honeybees; Opioid system; Stinging response; Stress-induced analgesia; isopentyl acetate; naloxone; pheromone; analgesia; animal experiment; article; controlled study; electric shock; honeybee; nonhuman; priority journal; stress
Año:1997
Volumen:63
Número:1
Página de inicio:75
Página de fin:80
DOI: http://dx.doi.org/10.1016/S0031-9384(97)00391-0
Título revista:Physiology and Behavior
Título revista abreviado:PHYSIOL. BEHAV.
ISSN:00319384
CODEN:PHBHA
CAS:isopentyl acetate, 123-92-2; naloxone, 357-08-4, 465-65-6
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319384_v63_n1_p75_Nunez

Referencias:

  • Abel, E., Alarm substance emitted by rats in the forced-swim test is a low volatile pheromone (1991) Physiol. Behav., 50, pp. 723-727
  • Balderrama, N., Diaz, H., Sequeda, A., Núñez, J.A., Maldonado, H., Behavioral and pharmacological analysis of the stinging response in Africanized and Italian bees (1987) Neurobiology and Behavior of Honeybees, pp. 121-128. , R. Menzel, & A. Mercer. Berlin: Springer
  • Butler, C.G., Free, J.B., The behaviour of worker honeybees at the hive entrance (1952) Behaviour, 4, pp. 262-292
  • Fanselow, M.S., , Odors released by stressed rats produce opioid analgesia in unstressed rats (1985) Behav. Neurosci., 99, pp. 589-592
  • Fanselow, M.S., Conditioned fear-induced opiate analgesia: A competing motivational state theory of stress analgesia (1986) Ann. NY Acad. Sci., 467, pp. 40-54
  • Ford, R., Jackson, D.M., Tetrault, L., Torres, J.C., Assanah, P., ; Harper, J; Leung, M (1986) K.; Stefano, G. B. a Behavioral Role for Enkephalins in Regulating Locomotor Activity in the Insects Leucophaea Maderae: Evidence for High Affinity Kappa-like Opioid Binding Sites. Comp. Biochem. Physiol., 85, pp. 61-66
  • Free, J.B., (1987) Pheromones of Social Bees, , New York: Comstock
  • Frisch, K., (1965) V, , Tanzsprache und Orientierung der Bienen. Berlin: Springer
  • Harrison, L.M., Kastin, A.J., Weber, J.T., Banks, W.A., Hurley, D.L., Zadina, J.E., The opiate system in invertebrates (1994) Peptides, 15, pp. 1309-1329
  • Jaffe, K., Blanco, M.E., Involvement of amino acids, opioids, nitric oxide, and NMDA receptors in learning and memory consolidation in crickets (1994) Pharmacol. Biochem. Behav., 47, pp. 493-496
  • Kavaliers, M., Guglick, M.A., Hirst, M., Opioid involvement in the control of feeding in an insect, the American cockroach (1987) Life Sci., 40, pp. 665-672
  • Kavaliers, M., Hirst, M., Naloxone-reversible stress-induced feeding and analgesia in the slug Limax maximus (1986) Life Sci., 38, pp. 2203-2209
  • Maldonado, H., Miralto, A., Effect of morphine and naloxone on a defensive response of the Mantis Shrimp (Squilla mantis) (1982) J. Comp. Physiol. a, 147, pp. 455-459
  • Miller, R.J., Cuatrecasas, P., Enkephalins and endorphins (1978) Vitam. Horm., 36, pp. 297-382
  • Núñez, J.A., Denti, A., Respuesta de abejas recolectoras a un estímulo nociceptivo (1970) Acta. Physiol. Lat., 20, pp. 140-146
  • Núñez, J.A., Maldonado, H., Miralto, A., Balderrama, N., The stinging response of the honeybee: Effects of morphine, naloxone and some opioid peptides (1983) Pharm. Biochem. Behav., 19, pp. 921-924
  • Watkins, L.R., Mayer, D.J., Multiple endogenous opiate and non-opiate analgesia systems: Evidence of their existence and clinical implications (1986) Ann. NY Acad. Sci., 467, pp. 273-299
  • Zabala, N.A., Miralto, A., Maldonado, H., Núñez, J.A., Jaffe, K., Calderon, L.D., Opiate receptor in praying mantis: Effect of morphine and naloxone (1984) Pharmacol. Biochem. Behav., 20, pp. 683-687
  • Zar, J.H., (1985) Biostatistical Analysis 2nd Ed., , New Jersey: Prentice Hall

Citas:

---------- APA ----------
Núñez, J., Almeida, L., Balderrama, N. & Giurfa, M. (1997) . Alarm pheromone induces stress analgesia via an opioid system in the honeybee. Physiology and Behavior, 63(1), 75-80.
http://dx.doi.org/10.1016/S0031-9384(97)00391-0
---------- CHICAGO ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. "Alarm pheromone induces stress analgesia via an opioid system in the honeybee" . Physiology and Behavior 63, no. 1 (1997) : 75-80.
http://dx.doi.org/10.1016/S0031-9384(97)00391-0
---------- MLA ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. "Alarm pheromone induces stress analgesia via an opioid system in the honeybee" . Physiology and Behavior, vol. 63, no. 1, 1997, pp. 75-80.
http://dx.doi.org/10.1016/S0031-9384(97)00391-0
---------- VANCOUVER ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. Alarm pheromone induces stress analgesia via an opioid system in the honeybee. PHYSIOL. BEHAV. 1997;63(1):75-80.
http://dx.doi.org/10.1016/S0031-9384(97)00391-0