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Changes of the stinging response threshold of Apis mellifera a scutellata were measured on foragers fixed on a holder and stimulated with an electric shock as a noxious stimulus. The threshold of responsiveness to the noxious stimulus increased when bees were previously stimulated with isopentyl acetate, which is a main component of the alarm pheromone of the sting chamber. This effect is antagonised by previous injection of naloxone-hydrochloride (Endo Laboratories Inc.). Results suggest that in the honeybee an endogenous opioid system activated by isopentyl acetate is responsible for modulation of perception for nociceptive stimuli. The resulting stress-induced analgesia in the defender bee would reduce its probability of withdrawal thus increasing its efficiency against enemies.


Documento: Artículo
Título:Alarm pheromone induces stress analgesia via an opioid system in the honeybee
Autor:Núñez, J.; Almeida, L.; Balderrama, N.; Giurfa, M.
Filiación:Laboratory of Insect Physiology, Dept. Biol. Sci., FCEyN, Univ. B., Buenos Aires, Argentina
Instituto Zoologia Agricola, Facultad Agronomía, Universidad Central de Venezuela, Aptdo. Postal 4579, Maracay 2101, Aragua, Venezuela
Institut für Neurobiologie, Freie Universität Berlin, Königin-Luise-Str. 28/30, 14195 Berlin, Germany
Palabras clave:Alarm pheromone; Honeybees; Opioid system; Stinging response; Stress-induced analgesia; isopentyl acetate; naloxone; pheromone; analgesia; animal experiment; article; controlled study; electric shock; honeybee; nonhuman; priority journal; stress
Página de inicio:75
Página de fin:80
Título revista:Physiology and Behavior
Título revista abreviado:PHYSIOL. BEHAV.
CAS:isopentyl acetate, 123-92-2; naloxone, 357-08-4, 465-65-6


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---------- APA ----------
Núñez, J., Almeida, L., Balderrama, N. & Giurfa, M. (1997) . Alarm pheromone induces stress analgesia via an opioid system in the honeybee. Physiology and Behavior, 63(1), 75-80.
---------- CHICAGO ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. "Alarm pheromone induces stress analgesia via an opioid system in the honeybee" . Physiology and Behavior 63, no. 1 (1997) : 75-80.
---------- MLA ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. "Alarm pheromone induces stress analgesia via an opioid system in the honeybee" . Physiology and Behavior, vol. 63, no. 1, 1997, pp. 75-80.
---------- VANCOUVER ----------
Núñez, J., Almeida, L., Balderrama, N., Giurfa, M. Alarm pheromone induces stress analgesia via an opioid system in the honeybee. PHYSIOL. BEHAV. 1997;63(1):75-80.