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Abstract:

The effect of melatonin on luteinizing hormone (LH) release was studied in castrated female rats injected with estradiol and progesterone. Melatonin administered s.c. twice daily for 6 days exerted a biphasic. dose-related effect on LH release, the lowest dose (125 ó/100 g body weight) being stimulatory and the highest (250 μg/IOO g body weight) inhibitory. Superior cervical ganglionectomy negated the inhibitory effect of the high melatonin dose on steroid-induced LH release. Rather melatonin injection to ganglionectomized rats resulted in significantly higher serum LH values than those of animals injected with estradiol and progesterone alone. Melatonin treatment failed to modify postcastration serum LH levels. © 1979 S. Karger AG, Basel.

Registro:

Documento: Artículo
Título:Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats
Autor:Moguilevsky, J.A.; Faigón, M.R.; Scacchi, P.; Cardinali, D.P.
Filiación:Departamento de Endocrinologia, Ceniro de Invesligaciones Médicas "Albert Einstein' (CIMAE), Centro de Estudios Farmacológicos y de Principios Naturales, Buenos Aires, Argentina
Palabras clave:LH release; Pineal gland Melatonin; Superior cervical ganglion; estradiol; melatonin; progesterone; animal experiment; castration; dose response; drug response; luteinizing hormone release; ovariectomy; rat; superior cervical ganglionectomy; Animal; Castration; Estradiol; Female; Ganglia, Sympathetic; Luteinizing Hormone; Melatonin; Progesterone; Rats
Año:1979
Volumen:29
Número:3
Página de inicio:163
Página de fin:168
DOI: http://dx.doi.org/10.1159/000122918
Título revista:Neuroendocrinology
Título revista abreviado:Neuroendocrinology
ISSN:00283835
CAS:estradiol, 50-28-2; melatonin, 73-31-4; progesterone, 57-83-0; Estradiol, 50-28-2; Luteinizing Hormone, 9002-67-9; Melatonin, 73-31-4; Progesterone, 57-83-0
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00283835_v29_n3_p163_Moguilevsky

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Citas:

---------- APA ----------
Moguilevsky, J.A., Faigón, M.R., Scacchi, P. & Cardinali, D.P. (1979) . Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats. Neuroendocrinology, 29(3), 163-168.
http://dx.doi.org/10.1159/000122918
---------- CHICAGO ----------
Moguilevsky, J.A., Faigón, M.R., Scacchi, P., Cardinali, D.P. "Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats" . Neuroendocrinology 29, no. 3 (1979) : 163-168.
http://dx.doi.org/10.1159/000122918
---------- MLA ----------
Moguilevsky, J.A., Faigón, M.R., Scacchi, P., Cardinali, D.P. "Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats" . Neuroendocrinology, vol. 29, no. 3, 1979, pp. 163-168.
http://dx.doi.org/10.1159/000122918
---------- VANCOUVER ----------
Moguilevsky, J.A., Faigón, M.R., Scacchi, P., Cardinali, D.P. Effect of melatonin and superior cervical ganglioectomy on luteinizing hormone on release induced by estradiol-progesterone in castrated rats. Neuroendocrinology. 1979;29(3):163-168.
http://dx.doi.org/10.1159/000122918