Registro:

Referencias:

• Li, R., Bowerman, B., Symmetry breaking in biology (2010) Cold Spring Harb Perspect Biol, 2 (3), p. a003475
• Macnab, R.M., Koshland, D.E., Jr., The gradient-sensing mechanism in bacterial chemotaxis (1972) Proc Natl Acad Sci USA, 69 (9), pp. 2509-2512
• Swaney, K.F., Huang, C.H., Devreotes, P.N., Eukaryotic chemotaxis: A network of signaling pathways controls motility, directional sensing, and polarity (2010) Annu Rev Biophys, 39, pp. 265-289
• Segall, J.E., Polarization of yeast cells in spatial gradients of alpha mating factor (1993) Proc Natl Acad Sci USA, 90 (18), pp. 8332-8336
• Zigmond, S.H., Chemotactic response of neutrophils (1989) Am J Respir Cell Mol Biol, 1 (6), pp. 451-453
• Arkowitz, R.A., Chemical gradients and chemotropism in yeast (2009) Cold Spring Harb Perspect Biol, 1 (2), p. a001958
• Slaughter, B.D., Smith, S.E., Li, R., Symmetry breaking in the life cycle of the budding yeast (2009) Cold Spring Harb Perspect Biol, 1 (3), p. a003384
• Jackson, C.L., Hartwell, L.H., Courtship in S. Cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal (1990) Cell, 63 (5), pp. 1039-1051
• Jenness, D.D., Burkholder, A.C., Hartwell, L.H., Binding of alpha-factor pheromone to yeast a cells: Chemical and genetic evidence for an alpha-factor receptor (1983) Cell, 35 (2), pp. 521-529
• Ayscough, K.R., Drubin, D.G., A role for the yeast actin cytoskeleton in pheromone receptor clustering and signalling (1998) Curr Biol, 8 (16), pp. 927-930
• Moore, T.I., Chou, C.S., Nie, Q., Jeon, N.L., Yi, T.M., Robust spatial sensing of mating pheromone gradients by yeast cells (2008) PLoS ONE, 3 (12), p. e3865
• Colman-Lerner, A., Regulated cell-to-cell variation in a cell-fate decision system (2005) Nature, 437 (7059), pp. 699-706
• Yi, T.M., Kitano, H., Simon, M.I., A quantitative characterization of the yeast heterotrimeric G protein cycle (2003) Proc Natl Acad Sci USA, 100 (19), pp. 10764-10769
• Yu, R.C., Negative feedback that improves information transmission in yeast signalling (2008) Nature, 456 (7223), pp. 755-761
• Jenness, D.D., Burkholder, A.C., Hartwell, L.H., Binding of alpha-factor pheromone to Saccharomyces cerevisiae a cells: Dissociation constant and number of binding sites (1986) Mol Cell Biol, 6 (1), pp. 318-320
• Bajaj, A., A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast (2004) Biochemistry, 43 (42), pp. 13564-13578
• Pruzansky, J.J., Patterson, R., Binding constants of IgE receptors on human blood basophils for IgE (1986) Immunology, 58 (2), pp. 257-262
• Mellman, I.S., Unkeless, J.C., Purification of a functional mouse Fc receptor through the use of a monoclonal antibody (1980) J Exp Med, 152 (4), pp. 1048-1069
• Herkenham, M., Cannabinoid receptor localization in brain (1990) Proc Natl Acad Sci USA, 87 (5), pp. 1932-1936
• Wang, H.M., Smith, K.A., The interleukin 2 receptor. Functional consequences of its bimolecular structure (1987) J Exp Med, 166 (4), pp. 1055-1069
• Hughes, R.J., Boyle, M.R., Brown, R.D., Taylor, P., Insel, P.A., Characterization of coexisting alpha 1- and beta 2-adrenergic receptors on a cloned muscle cell line, BC3H-1 (1982) Mol Pharmacol, 22 (2), pp. 258-266
• Horwitz, E.M., Jenkins, W.T., Hoosein, N.M., Gurd, R.S., Kinetic identification of a twostate glucagon receptor system in isolated hepatocytes. Interconversion of homogeneous receptors (1985) J Biol Chem, 260 (16), pp. 9307-9315
• Marasco, W.A., Feltner, D.E., Ward, P.A., Formyl peptide chemotaxis receptors on the rat neutrophil: Experimental evidence for negative cooperativity (1985) J Cell Biochem, 27 (4), pp. 359-375
• Bajzer, Z., Myers, A.C., Vuk-Pavlovic, S., Binding, internalization, and intracellular processing of proteins interacting with recycling receptors. A kinetic analysis (1989) J Biol Chem, 264 (23), pp. 13623-13631
• Ciechanover, A., Schwartz, A.L., Dautry-Varsat, A., Lodish, H.F., Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents (1983) J Biol Chem, 258 (16), pp. 9681-9689
• Waters, C.M., Oberg, K.C., Carpenter, G., Overholser, K.A., Rate constants for binding, dissociation, and internalization of EGF: Effect of receptor occupancy and ligand concentration (1990) Biochemistry, 29 (14), pp. 3563-3569
• Lipkin, E.W., Teller, D.C., De Haën, C., Kinetics of insulin binding to rat white fat cells at 15 degrees C (1986) J Biol Chem, 261 (4), pp. 1702-1711
• Zigmond, S.H., Sullivan, S.J., Lauffenburger, D.A., Kinetic analysis of chemotactic peptide receptor modulation (1982) J Cell Biol, 92 (1), pp. 34-43
• Akiyama, S.K., Yamada, K.M., The interaction of plasma fibronectin with fibroblastic cells in suspension (1985) J Biol Chem, 260 (7), pp. 4492-4500
• Matsui, K., Boniface, J.J., Steffner, P., Reay, P.A., Davis, M.M., Kinetics of T-cell receptor binding to peptide/I-Ek complexes: Correlation of the dissociation rate with T-cell responsiveness (1994) Proc Natl Acad Sci USA, 91 (26), pp. 12862-12866
• Sklar, L.A., Sayre, J., McNeil, V.M., Finney, D.A., Competitive binding kinetics in ligandreceptor- competitor systems. Rate parameters for unlabeled ligands for the formyl peptide receptor (1985) Mol Pharmacol, 28 (4), pp. 323-330
• Ueda, M., Sako, Y., Tanaka, T., Devreotes, P., Yanagida, T., Single-molecule analysis of chemotactic signaling in Dictyostelium cells (2001) Science, 294 (5543), pp. 864-867
• Morton, T., Li, J., Cook, R., Chaiken, I., Mutagenesis in the C-terminal region of human interleukin 5 reveals a central patch for receptor alpha chain recognition (1995) Proc Natl Acad Sci USA, 92 (24), pp. 10879-10883
• Clements, J.D., Lester, R.A., Tong, G., Jahr, C.E., Westbrook, G.L., The time course of glutamate in the synaptic cleft (1992) Science, 258 (5087), pp. 1498-1501
• Hoffmann, C., A FlAsH-based FRET approach to determine G proteincoupled receptor activation in living cells (2005) Nat Methods, 2 (3), pp. 171-176
• Krampfl, K., Control of kinetic properties of GluR2 flop AMPA-type channels: Impact of R/G nuclear editing (2002) Eur J Neurosci, 15 (1), pp. 51-62
• Toshima, J.Y., Spatial dynamics of receptor-mediated endocytic trafficking in budding yeast revealed by using fluorescent alpha-factor derivatives (2006) Proc Natl Acad Sci USA, 103 (15), pp. 5793-5798
• Konopka, J.B., Jenness, D.D., Hartwell, L.H., The C-terminus of the S. Cerevisiae alphapheromone receptor mediates an adaptive response to pheromone (1988) Cell, 54 (5), pp. 609-620
• Koshland, D.E., Jr., Goldbeter, A., Stock, J.B., Amplification and adaptation in regulatory and sensory systems (1982) Science, 217 (4556), pp. 220-225
• Basu, S., Mehreja, R., Thiberge, S., Chen, M.-T.T., Weiss, R., Spatiotemporal control of gene expression with pulse-generating networks (2004) Proc Natl Acad Sci USA, 101 (17), pp. 6355-6360
• Jones, M.V., Westbrook, G.L., The impact of receptor desensitization on fast synaptic transmission (1996) Trends Neurosci, 19 (3), pp. 96-101
• Tyson, J.J., Novák, B., Functional motifs in biochemical reaction networks (2010) Annu Rev Phys Chem, 61, pp. 219-240
• Alon, U., (2006) An Introduction to Systems Biology: Design Principles of Biological Circuits, , (Chapman & Hall, London)
• Dorer, R., Pryciak, P.M., Hartwell, L.H., Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients (1995) J Cell Biol, 131 (4), pp. 845-861
• Whiteway, M.S., Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p (1995) Science, 269 (5230), pp. 1572-1575
• Pryciak, P.M., Huntress, F.A., Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gbetagamma complex underlies activation of the yeast pheromone response pathway (1998) Genes Dev, 12 (17), pp. 2684-2697
• Keenan, T.M., Hsu, C.-H., Folch, A., Microfluidic "jets" for generating steadystate gradients of soluble molecules on open surfaces (2006) Appl Phys Lett, 89 (11), pp. 1141031-1141033
• Shaner, N.C., A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum (2013) Nat Methods, 10 (5), pp. 407-409
• Butty, A.C., A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization (2002) EMBO J, 21 (7), pp. 1565-1576
• Irazoqui, J.E., Gladfelter, A.S., Lew, D.J., Scaffold-mediated symmetry breaking by Cdc42p (2003) Nat Cell Biol, 5 (12), pp. 1062-1070
• Chenevert, J., Corrado, K., Bender, A., Pringle, J., Herskowitz, I., A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains (1992) Nature, 356 (6364), pp. 77-79
• Casamayor, A., Snyder, M., Bud-site selection and cell polarity in budding yeast (2002) Curr Opin Microbiol, 5 (2), pp. 179-186
• Zahner, J.E., Harkins, H.A., Pringle, J.R., Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae (1996) Mol Cell Biol, 16 (4), pp. 1857-1870
• Altschuler, S.J., Angenent, S.B., Wang, Y., Wu, L.F., On the spontaneous emergence of cell polarity (2008) Nature, 454 (7206), pp. 886-889
• Nern, A., Arkowitz, R.A., A GTP-exchange factor required for cell orientation (1998) Nature, 391 (6663), pp. 195-198
• Nern, A., Arkowitz, R.A., A Cdc24p-Far1p-Gbetagamma protein complex required for yeast orientation during mating (1999) J Cell Biol, 144 (6), pp. 1187-1202
• Lisman, J.E., Raghavachari, S., Tsien, R.W., The sequence of events that underlie quantal transmission at central glutamatergic synapses (2007) Nat Rev Neurosci, 8 (8), pp. 597-609
• Kim, J.Y., Borleis, J.A., Devreotes, P.N., Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: Receptor subtypes activate common responses at different agonist concentrations (1998) Dev Biol, 197 (1), pp. 117-128
• Sourjik, V., Wingreen, N.S., Responding to chemical gradients: Bacterial chemotaxis (2012) Curr Opin Cell Biol, 24 (2), pp. 262-268
• Friedlander, T., Brenne, N., Adaptive response and enlargement of dynamic range (2011) Math Biosci Eng, 8 (2), pp. 515-528
• Becker, V., Covering a broad dynamic range: Information processing at the erythropoietin receptor (2010) Science, 328 (5984), pp. 1404-1408
• Behar, M., Hao, N., Dohlman, H.G., Elston, T.C., Dose-to-duration encoding and signaling beyond saturation in intracellular signaling networks (2008) PLOS Comput Biol, 4 (10), p. e1000197
• Edelstein, S.J., Stefan, M.I., Le Novère, N., Ligand depletion in vivo modulates the dynamic range and cooperativity of signal transduction (2010) PLoS ONE, 5 (1), p. e8449
• Nevozhay, D., Adams, R.M., Murphy, K.F., Josic, K., Balázsi, G., Negative autoregulation linearizes the dose-response and suppresses the heterogeneity of gene expression (2009) Proc Natl Acad Sci USA, 106 (13), pp. 5123-5128
• Madar, D., Dekel, E., Bren, A., Alon, U., Negative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coli (2011) BMC Syst Biol, 5, p. 111
• Bergmann, S., Pre-steady-state decoding of the Bicoid morphogen gradient (2007) PLoS Biol, 5 (2), p. e46
• Tamari, Z., Barkai, N., Improved readout precision of the Bicoid morphogen gradient by early decoding (2012) J Biol Phys, 38 (2), pp. 317-329
• Mackay, V.L., The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin (1988) Proc Natl Acad Sci USA, 85 (1), pp. 55-59
• Andrews, S.S., Addy, N.J., Brent, R., Arkin, A.P., Detailed simulations of cell biology with Smoldyn 2. 1 (2010) PLOS Comput Biol, 6 (3), p. e1000705
• Rappaport, N., Barkai, N., Disentangling signaling gradients generated by equivalent sources (2012) J Biol Phys, 38 (2), pp. 267-278
• Kuo, C.-C.C., Inhibitory GEF phosphorylation provides negative feedback in the yeast polarity circuit (2014) Curr Biol, 24 (7), pp. 753-759
• Wu, C.-F.F., Lew, D.J., Beyond symmetry-breaking: Competition and negative feedback in GTPase regulation (2013) Trends Cell Biol, 23 (10), pp. 476-483
• Lauffenburger, D.A., Linderman, J.J., (1993) Receptors: Models for Binding, Trafficking, and Signaling, , (Oxford Univ Press, New York)
• Ma, W., Trusina, A., El-Samad, H., Lim, W.A., Tang, C., Defining network topologies that can achieve biochemical adaptation (2009) Cell, 138 (4), pp. 760-773
• Kholodenko, B.N., Hancock, J.F., Kolch, W., Signalling ballet in space and time (2010) Nat Rev Mol Cell Biol, 11 (6), pp. 414-426
• Guthrie, C., Fink, G.R., (1991) Methods in Enzymology, Guide to Yeast Genetics and Molecular Biology, , (Academic, San Diego)
• Gordon, Single-cell quantification of molecules and rates using opensource microscope-based cytometry (2007) Nat Methods, 4 (2), pp. 175-181
• Bush, A., Colman-Lerner, A., Quantitative measurement of protein relocalization in live cells (2013) Biophys J, 104 (3), pp. 727-736
• Monahan, J., Gewirth, A.A., Nuzzo, R.G., A method for filling complex polymeric microfluidic devices and arrays (2001) Anal Chem, 73 (13), pp. 3193-3197
• Liu, B., Parts-per-million of polyethylene glycol as a non-interfering blocking agent for homogeneous biosensor development (2013) Anal Chem, 85 (21), pp. 10045-10050
• Efron, B., Tibshirani, R., (1994) An Introduction to the Bootstrap, , (Chapman and Hall, New York)
• Cedersund, G., Roll, J., Systems biology: Model based evaluation and comparison of potential explanations for given biological data (2009) FEBS J, 276 (4), pp. 903-922
• Butty, A.C., Pryciak, P.M., Huang, L.S., Herskowitz, I., Peter, M., The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating (1998) Science, 282 (5393), pp. 1511-1516
• Leeuw, T., Pheromone response in yeast: Association of Bem1p with proteins of the MAP kinase cascade and actin (1995) Science, 270 (5239), pp. 1210-1213

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------