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Abstract:

Cytogenetic studies in Cebus spp. have highlighted a peculiar genomic feature: the presence of conspicuous regions of extracentromeric heterochromatin distributed throughout the karyotype. This study investigates the distribution, variability and composition of heterochromatin and their possible implications for genome dynamics. We performed a molecular cytogenetic analysis in 253 individuals from seven of the 12 currently recognized species. The proportion of heterochromatin was related to genome size and ranked, from smallest to largest, from C. xanthosternos to C. albifrons. Interspecies comparative genome hybridization analyses suggested that the differences among species are not related to heterochromatin content but to changes in the Y chromosome. The pattern revealed by DAPI/CMA3 staining showed that Cebus heterochromatic DNA has a GC-rich composition. The distribution frequencies of heteromorphisms and polymorphisms were not randomly distributed, because a distinguishable pattern could be recognized for each group. Cebus cay and C. nigritus had a higher level of heterochromatin variability than previously reported. In conclusion, the wide variability among species of the genus Cebus is mostly due to the repetitive DNA fraction of its genome. © 2017 The Linnean Society of London, Biological Journal of the Linnean Society.

Registro:

Documento: Artículo
Título:What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?
Autor:Nieves, M.; Fantini, L.; Mudry, M.D.
Filiación:Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Ecologia, Genetica y Evolucion, Grupo de Investigación en Biología Evolutiva (GIBE), Ciudad Universitaria, Pabellón 2, 4o piso, Laboratorios 43 y 46, Buenos Aires, C1428EGA, Argentina
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-UBA, Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA), Ciudad Universitaria, Pabellón 2, 4o piso, Buenos Aires, C1428EGA, Argentina
Universidad Nacional A. Jauretche, Buenos Aires, Argentina
Palabras clave:Cebus; GC content; Genome dynamics; Genome size; Heterochromatin; ICGH; Molecular cytogenetics; Neotropical primates; Polymorphisms; chromosome; cytogenetics; genome; genomics; hybridization; molecular analysis; polymorphism; primate; Cebus; Cebus albifrons; Cebus xanthosternos; Platyrrhini; Primates
Año:2018
Volumen:123
Número:1
Página de inicio:113
Página de fin:124
DOI: http://dx.doi.org/10.1093/biolinnean/blx121
Título revista:Biological Journal of the Linnean Society
Título revista abreviado:Biol. J. Linn. Soc.
ISSN:00244066
CODEN:BJLSB
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00244066_v123_n1_p113_Nieves

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Citas:

---------- APA ----------
Nieves, M., Fantini, L. & Mudry, M.D. (2018) . What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?. Biological Journal of the Linnean Society, 123(1), 113-124.
http://dx.doi.org/10.1093/biolinnean/blx121
---------- CHICAGO ----------
Nieves, M., Fantini, L., Mudry, M.D. "What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?" . Biological Journal of the Linnean Society 123, no. 1 (2018) : 113-124.
http://dx.doi.org/10.1093/biolinnean/blx121
---------- MLA ----------
Nieves, M., Fantini, L., Mudry, M.D. "What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?" . Biological Journal of the Linnean Society, vol. 123, no. 1, 2018, pp. 113-124.
http://dx.doi.org/10.1093/biolinnean/blx121
---------- VANCOUVER ----------
Nieves, M., Fantini, L., Mudry, M.D. What do we know about the heterochromatin of capuchin monkeys (Cebus: Platyrrhini)?. Biol. J. Linn. Soc. 2018;123(1):113-124.
http://dx.doi.org/10.1093/biolinnean/blx121