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Abstract:

The effect of exercise on mitochondria respiration was studied in gastrocnemius muscle of ovariectomized rats, pseudopregnant rats, and estrous rats. The estrous cycles were followed by vaginal smears. Rats were made pseudopregnant (PSP) by 45 s cervical stimulation with a glass rod on the day of estrous. The treadmill protocol (21 m/min, 10 grade uphill) induced a significant decrease in state 3 oxygen consumption (oxidative phosphorylation) in estrous (0.26 ± 0.02 vs. 0.49 ± 0.05 μatoms O min-1 mg protein-1) and ovariectomized rats (0.18 ± 0.03 vs. 0.40 ± 0.03 μatoms O min-1 mg protein-1). In contrast, pseudopregnant and progesterone-treated ovariectomized rats did not decrease state 3 nor state 4 respiratory rates. These results show that the effect of exercise on mitochondria respiration does vary according to the hormonal status. © 2001 Elsevier Science Inc.

Registro:

Documento: Artículo
Título:Exercise and ovarian steroid hormones: Their effects on mitochondrial respiration
Autor:Gigli, I.; Bussmann, L.E.
Filiación:Instituto de Biología y Medicina Experimental, CONICET, Vuelta de Obligado 2490, Buenos Aires (1428), Argentina
Departamento de Medicina, Facultad de Veterinarias, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Exercise; Mitochondria respiration; Ovarian hormones; Rat; Skeletal muscle; citrate synthase; glutamic acid; lactic acid; malate dehydrogenase; maleic acid; progesterone; pyruvic acid; succinate dehydrogenase; succinic acid; animal experiment; animal model; animal tissue; article; breathing rate; controlled study; enzyme activity; estrus cycle; female; gastrocnemius muscle; lactate blood level; metabolite; mitochondrial respiration; nonhuman; ovariectomy; oxygen consumption; pseudopregnancy; rat; treadmill exercise; vagina smear; Animals; Cell Respiration; Estrogens; Estrus; Female; Glycogen; Hormone Replacement Therapy; Lactic Acid; Malate Dehydrogenase; Mitochondria, Muscle; Muscle, Skeletal; Ovariectomy; Oxygen Consumption; Physical Conditioning, Animal; Progesterone; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Succinate Dehydrogenase; Water
Año:2001
Volumen:68
Número:13
Página de inicio:1505
Página de fin:1514
DOI: http://dx.doi.org/10.1016/S0024-3205(01)00954-7
Título revista:Life Sciences
Título revista abreviado:Life Sci.
ISSN:00243205
CODEN:LIFSA
CAS:Estrogens; Glycogen, 9005-79-2; Lactic Acid, 50-21-5; Malate Dehydrogenase, EC 1.1.1.37; Progesterone, 57-83-0; Succinate Dehydrogenase, EC 1.3.99.1; Water, 7732-18-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00243205_v68_n13_p1505_Gigli

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Citas:

---------- APA ----------
Gigli, I. & Bussmann, L.E. (2001) . Exercise and ovarian steroid hormones: Their effects on mitochondrial respiration. Life Sciences, 68(13), 1505-1514.
http://dx.doi.org/10.1016/S0024-3205(01)00954-7
---------- CHICAGO ----------
Gigli, I., Bussmann, L.E. "Exercise and ovarian steroid hormones: Their effects on mitochondrial respiration" . Life Sciences 68, no. 13 (2001) : 1505-1514.
http://dx.doi.org/10.1016/S0024-3205(01)00954-7
---------- MLA ----------
Gigli, I., Bussmann, L.E. "Exercise and ovarian steroid hormones: Their effects on mitochondrial respiration" . Life Sciences, vol. 68, no. 13, 2001, pp. 1505-1514.
http://dx.doi.org/10.1016/S0024-3205(01)00954-7
---------- VANCOUVER ----------
Gigli, I., Bussmann, L.E. Exercise and ovarian steroid hormones: Their effects on mitochondrial respiration. Life Sci. 2001;68(13):1505-1514.
http://dx.doi.org/10.1016/S0024-3205(01)00954-7