Navegar

Colección

Datos Estadísticas

Artículo

Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

Autoimplantation of an ovary, containing fresh corpora lutea, into the spleen of an ovariectomized rat is followed by strong luteinization and size increase of the grafted gonad. Thus, large amounts of luteal tissue for biochemical studies, and their histological controls are available. Furthermore, progesterone secretion can be easily determined in samples collected from the portal vein. Since prolactin has been implicated in the control of luteal tissue, the role of this hormone on hLH binding and progesterone secretion was determined. Different levels of endogenous serum prolactin were achieved by pharmacological treatments with neurotropic agents. Scatchard plots of 125-I hLH binding data derived from luteoma particulate fractions revealed the presence of one type of binding site with high affinity. At the same time as binding increased, prolactinemia augmented, with a high correlation (R:0.99) between prolactinemia and LH binding. Moreover, progesterone secreted by the luteoma increased as LH binding sites augmented (R:0,97). It is concluded that a high correlation between prolactinemia and LH binding, as well as between this last parameter and progesterone output exists in the experimental luteoma. © 1984.

Registro:

Documento: Artículo
Título:High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma
Autor:Lux, V.A.R.; Tesone, M.; Larrea, G.A.; Libertun, C.
Filiación:Instituto de Biología y Medicina Experimental. Obligado 2490, 1428 Buenos Aires, Argentina
Palabras clave:luteinizing hormone receptor; progesterone; radioisotope; animal cell; corpus luteum; endocrine system; female genital system; luteinization; luteinizing hormone i 125; nonhuman; ovary graft; priority journal; prolactin blood level; rat; Animal; Corpus Luteum; Female; Kinetics; Luteinizing Hormone; Ovary; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, LH; Support, Non-U.S. Gov't; Transplantation, Autologous
Año:1984
Volumen:35
Número:23
Página de inicio:2345
Página de fin:2352
DOI: http://dx.doi.org/10.1016/0024-3205(84)90526-5
Título revista:Life Sciences
Título revista abreviado:Life Sci.
ISSN:00243205
CODEN:LIFSA
CAS:progesterone, 57-83-0; Luteinizing Hormone, 9002-67-9; Progesterone, 57-83-0; Prolactin, 9002-62-4; Receptors, Cell Surface; Receptors, LH
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00243205_v35_n23_p2345_Lux

Referencias:

  • Biskind, Biskind, Development of Tumors in the Rat Ovary After Transplantation into the Spleen. (1944) Experimental Biology and Medicine, 55, pp. 176-179. , 2nd edition
  • Fels, Moguilevsky, Libertun, (1968) Acta physiol. latinoam., 18, pp. 132-135
  • Leavitt, Carlson, Meyer, (1971) Endocrinology, 88, pp. 16-25
  • Uilenbroek, Tiller, de Jong, Vels, (1978) J. Endocr., 78, pp. 399-406
  • Dohler, Wutke, (1974) Endocrinology, 94, pp. 1595-1601
  • Ford, Yoshinaga, (1975) Endocrinology, 96, pp. 335-339
  • Advis, Ojeda, (1978) Endocrinology, 103, pp. 924-935
  • Garris, Rothchild, (1980) Endocrinology, 107, pp. 1112-1116
  • Taya, Greenwald, (1982) Endocrinol. Japan, 29, pp. 453-459
  • Garris, (1982) Proc. Soc. exp. Biol. Med., 170, pp. 203-208. , 2nd edition
  • Boehm, Plas-Roser, Aron, (1982) Experientia, 38, pp. 1253-1254
  • Ford, Yoshinaga, (1975) Biol. Reproduction, 13, pp. 353-357
  • Holt, Richards, Rees Midgley, Jr., Reichert, Jr., (1976) Endocrinology, 98, pp. 1005-1013
  • Richards, Williams, (1976) Endocrinology, 99, pp. 1571-1581
  • Smith, McLean, Neill, (1976) Endocrinology, 98, pp. 1370-1377
  • Mirakami, Takahashi, Suzuki, Homma, (1982) Endocrinology, 111, pp. 500-508
  • Moch, Niswender, (1983) Endocrinology, 113, pp. 259-264
  • Libertun, Larrea, Vacas, Cardinali, (1980) Endocrinology, 107, pp. 1905-1909
  • De Nicola, Weisenberg, Arakelian, Libertun, (1981) Endocrinology, 109, pp. 83-86
  • McLeod, Robyn, (1977) J. Endocrinol., 72, pp. 273-277
  • Fuller, Clemens, Kornfeld, Snoddy, Smalstig, Bach, (1979) Life Sciences, 24, pp. 375-382
  • Yen, Staam, Clemens, (1979) Life Sciences, 25, pp. 209-216
  • L'Herimite, Debusschere, (1982) Acta Endocrinol., 101, pp. 481-483
  • Zeballos, McCann, (1974) Proc. Soc. exp. Biol. Med., 145, pp. 415-420. , 2nd edition
  • Lowry, Rosebrough, Farr, Randall, (1951) J. Biol. Chem., 193, pp. 265-275
  • Thorell, Johanson, (1971) Biochem. Biophys. Acta, 251, pp. 363-369
  • Charreau, Calvo, Tesone, Valle, Barañao, (1978) J. Biol. Chem., 253, pp. 2504-2516
  • Tesone, Ladenheim, Oliveira-Filho, Chiauzzi, Foglia, Charreau, (1983) Proc. Soc. exp. Biol. Med, 174, pp. 123-131. , 2nd edition
  • Becu, Libertun, (1983) Endocrinology, 113, pp. 1980-1984
  • Pepe, Rothchild, (1972) Endocrinology, 91, pp. 1380-1384
  • Scatchard, THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS (1949) Annals of the New York Academy of Sciences, 51, pp. 660-672
  • Armdtrong, Miller, Knudsen, (1969) Endocrinology, 85, pp. 393-401
  • Wu, Weiss, (1976) Endocrinology, 98, pp. 1378-1389
  • Behrman, Grinwich, Hichens, Macdonald, (1978) Endocrinology, 103, pp. 349-357
  • Tesone, Chiauzzi, Oliveira-Filho, Charreau, (1981) Medicina, 41, pp. 755-756. , Abstract
  • Moguilevsky, Faigon, Swarcfarb, Scacchi, Cardinali, (1982) Physiopathology of Hypophyseal Disturbances and Diseases of Reproduction, pp. 49-59. , A.F. De Nicola, J.A. Blaquier, R. Soto, Alan R. Liss, New York
  • Grandison, Hodson, Chen, Advis, Simpkins, Meites, (1976) Neuroendocrinol., 23, pp. 206-215
  • Kalra, McCann, (1974) Neuroendocrinol., 15, pp. 79-91
  • Sawyer, (1979) Can. J. Physiol. Pharmacol., 57, pp. 667-680
  • Selmanoff, (1981) Endocrinology, 108, pp. 1716-1722

Citas:

---------- APA ----------
Lux, V.A.R., Tesone, M., Larrea, G.A. & Libertun, C. (1984) . High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma. Life Sciences, 35(23), 2345-2352.
http://dx.doi.org/10.1016/0024-3205(84)90526-5
---------- CHICAGO ----------
Lux, V.A.R., Tesone, M., Larrea, G.A., Libertun, C. "High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma" . Life Sciences 35, no. 23 (1984) : 2345-2352.
http://dx.doi.org/10.1016/0024-3205(84)90526-5
---------- MLA ----------
Lux, V.A.R., Tesone, M., Larrea, G.A., Libertun, C. "High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma" . Life Sciences, vol. 35, no. 23, 1984, pp. 2345-2352.
http://dx.doi.org/10.1016/0024-3205(84)90526-5
---------- VANCOUVER ----------
Lux, V.A.R., Tesone, M., Larrea, G.A., Libertun, C. High correlation between prolactinemia, 125-I hLH binding and progesterone secretion by an experimental luteoma. Life Sci. 1984;35(23):2345-2352.
http://dx.doi.org/10.1016/0024-3205(84)90526-5