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Abstract:

Tuberculosis (TB) transmission is enhanced by systematic exposure to an infectious individual. This enhancement usually takes place at either the home, workplace, and/or school (generalized household). Typical epidemiological models do not incorporate the impact of generalized households on the study of disease dynamics. Models that incorporate cluster (generalized household) effects and focus on their impact on TB's transmission dynamics are developed. Detailed models that consider the effect of casual infections, that is, those generated outside a cluster, are also presented. We find expressions for the Basic Reproductive Number as a function of cluster size. The formula for R0 separates the contributions of cluster and casual infections in the generation of secondary TB infections. Relationships between cluster and classical epidemic models are discussed as well as the concept of critical cluster size. (C) 2000 Academic Press.

Registro:

Documento: Artículo
Título:Transmission and dynamics of tuberculosis on generalized households
Autor:Aparicio, J.P.; Capurro, A.F.; Castillo-Chavez, C.
Filiación:Departamento De Física, Facultad De Ciencias Exactas Y Naturales, Ciudad Universitaria, 1428, Buenos Aires, Argentina
Departamento De Investigación, Universidad De Belgrano, Zabala 1851, Piso 12, 1426, Buenos Aires, Argentina
Laboratorio De Ecología, Universidad Nacional De Luján-CONICET, Ruta 5 y 7, 6700, Luján, Argentina
Theoretical Biology Institute, Cornell University, 431 Warren Hall, Ithaca, NY 14853-7801, United States
Department of Theoretical and Applied Mechanics, Cornell University, 317 Kimball Hall, Ithaca, NY 14853-1503, United States
Palabras clave:airborne particle; article; disease transmission; epidemic; household; model; priority journal; tuberculosis
Año:2000
Volumen:206
Número:3
Página de inicio:327
Página de fin:341
DOI: http://dx.doi.org/10.1006/jtbi.2000.2129
Título revista:Journal of Theoretical Biology
Título revista abreviado:J. Theor. Biol.
ISSN:00225193
CODEN:JTBIA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00225193_v206_n3_p327_Aparicio

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Citas:

---------- APA ----------
Aparicio, J.P., Capurro, A.F. & Castillo-Chavez, C. (2000) . Transmission and dynamics of tuberculosis on generalized households. Journal of Theoretical Biology, 206(3), 327-341.
http://dx.doi.org/10.1006/jtbi.2000.2129
---------- CHICAGO ----------
Aparicio, J.P., Capurro, A.F., Castillo-Chavez, C. "Transmission and dynamics of tuberculosis on generalized households" . Journal of Theoretical Biology 206, no. 3 (2000) : 327-341.
http://dx.doi.org/10.1006/jtbi.2000.2129
---------- MLA ----------
Aparicio, J.P., Capurro, A.F., Castillo-Chavez, C. "Transmission and dynamics of tuberculosis on generalized households" . Journal of Theoretical Biology, vol. 206, no. 3, 2000, pp. 327-341.
http://dx.doi.org/10.1006/jtbi.2000.2129
---------- VANCOUVER ----------
Aparicio, J.P., Capurro, A.F., Castillo-Chavez, C. Transmission and dynamics of tuberculosis on generalized households. J. Theor. Biol. 2000;206(3):327-341.
http://dx.doi.org/10.1006/jtbi.2000.2129