The incorporation of tritiated (+)-tembetarine chloride (reticuline methochloride) into sinomenine (in Sinomenium acutum) and into protopine (in Dicentra spectabilis) has been determined. By comparison with (+)-reticuline, an established intermediate in the biosynthesis of sinomenine and of protopine, (+)-tembetarine is an inefficient precursor.
| Documento: | Artículo |
| Título: | Phenol oxidation and biosynthesis. Part XIX. on the role of quaternary metho-salts in alkaloid biosynthesis |
| Autor: | Barton, D.H.R.; Boar, R.B.; Widdowson, D.A.; Deulofeu, V.; Albonico, S.M. |
| Filiación: | Imperial College, London S.W.7 Facultad de Ciencias Exactas y Naturales, Perú 222, Buenos Aires, Argentina Facultad de Farmacia y Bioquimica, Buenos Aires, Argentina |
| Palabras clave: | alkaloid; inorganic salt; isoquinoline derivative; phenol derivative; article; biosynthesis; chemistry; medicinal plant; metabolism; oxidation reduction reaction; Alkaloids; Chemistry; Isoquinolines; Oxidation-Reduction; Phenols; Plants, Medicinal; Salts |
| Año: | 1969 |
| Número: | 5 |
| Página de inicio: | 807 |
| Página de fin: | 808 |
| DOI: | http://dx.doi.org/10.1039/j39690000807 |
| Título revista: | Journal of the Chemical Society C: Organic |
| ISSN: | 00224952 |
| CAS: | Alkaloids; Isoquinolines; Phenols; Salts |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224952_v_n5_p807_Barton |
