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Abstract:

3β-Hydroxy-5-cholenic acid was synthesized from 3β-hydroxy-5-pregnen-20-one in nine steps. The procedure would permit the labelling of C-22, C-23, and/or C-24 of the bile-acid side chain by choice of the appropriate labelled reagent. © 1977.

Registro:

Documento: Artículo
Título:Synthesis of 3β-hydroxy-5-cholenic acid from 3β-hydroxy-5-pregnen-20-one aimed at the preparation of labelled steroid compounds
Autor:Burton, G.; Gros, E.G.
Filiación:Departamento de Quimica Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina
Palabras clave:carbon; cholane derivative; pregnenolone; sterol; radioisotope; article; infrared spectrophotometry; isotope labeling; methodology; nuclear magnetic resonance spectroscopy; optical rotation; synthesis; 3beta hydroxycholenic acid; in vitro study; steroidogenesis; theoretical study; Carbon Radioisotopes; Cholenes; Isotope Labeling; Magnetic Resonance Spectroscopy; Optical Rotation; Pregnenolone; Spectrophotometry, Infrared; Sterols
Año:1977
Volumen:8
Número:1
Página de inicio:69
Página de fin:72
DOI: http://dx.doi.org/10.1016/0022-4731(77)90219-9
Título revista:Journal of Steroid Biochemistry
Título revista abreviado:J. Steroid Biochem.
ISSN:00224731
CODEN:JSTBB
CAS:carbon, 7440-44-0; pregnenolone, 145-13-1; Carbon Radioisotopes; Cholenes; Pregnenolone, 145-13-1; Sterols
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224731_v8_n1_p69_Burton

Referencias:

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Citas:

---------- APA ----------
Burton, G. & Gros, E.G. (1977) . Synthesis of 3β-hydroxy-5-cholenic acid from 3β-hydroxy-5-pregnen-20-one aimed at the preparation of labelled steroid compounds. Journal of Steroid Biochemistry, 8(1), 69-72.
http://dx.doi.org/10.1016/0022-4731(77)90219-9
---------- CHICAGO ----------
Burton, G., Gros, E.G. "Synthesis of 3β-hydroxy-5-cholenic acid from 3β-hydroxy-5-pregnen-20-one aimed at the preparation of labelled steroid compounds" . Journal of Steroid Biochemistry 8, no. 1 (1977) : 69-72.
http://dx.doi.org/10.1016/0022-4731(77)90219-9
---------- MLA ----------
Burton, G., Gros, E.G. "Synthesis of 3β-hydroxy-5-cholenic acid from 3β-hydroxy-5-pregnen-20-one aimed at the preparation of labelled steroid compounds" . Journal of Steroid Biochemistry, vol. 8, no. 1, 1977, pp. 69-72.
http://dx.doi.org/10.1016/0022-4731(77)90219-9
---------- VANCOUVER ----------
Burton, G., Gros, E.G. Synthesis of 3β-hydroxy-5-cholenic acid from 3β-hydroxy-5-pregnen-20-one aimed at the preparation of labelled steroid compounds. J. Steroid Biochem. 1977;8(1):69-72.
http://dx.doi.org/10.1016/0022-4731(77)90219-9