Abstract:
A highly lipophilic form of aldosterone obtained both from incubations of 18-hydroxycorticosterone with quartered rat adrenals and by treatment of aldosterone with acid, was identified as an aldosterone dimer based on its 1H, 13C NMR and mass spectra. © 1985.
Registro:
Documento: |
Artículo
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Título: | A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer |
Autor: | Cozza, E.N.; Lantos, C.P.; Burton, G. |
Filiación: | Laboratorio de Esteroides, Departamento de Quimica Biológica, PRHOM (CONICET) Facultad de Ciencias Exactas y Naturales, Ciudad Universitaria, Pab. 2, 1428 Buenos Aires, Argentina Departamento de Química Orgáinica and UMYMFOR (CONICET-FCEN), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. 2, 1428 Buenos Aires, Argentina
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Palabras clave: | aldosterone; adrenal gland; animal cell; dimerization; endocrine system; nonhuman; priority journal; rat; Aldosterone; Animal; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Male; Rats; Spectrum Analysis, Mass |
Año: | 1985
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Volumen: | 23
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Número: | 4
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Página de inicio: | 511
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Página de fin: | 516
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DOI: |
http://dx.doi.org/10.1016/0022-4731(85)90200-6 |
Título revista: | Journal of Steroid Biochemistry
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Título revista abreviado: | J. Steroid Biochem.
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ISSN: | 00224731
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CODEN: | JSTBB
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CAS: | aldosterone, 52-39-1, 6251-69-0; Aldosterone, 52-39-1
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224731_v23_n4_p511_Cozza |
Referencias:
- Cozza, Burton, Ceballos, Lantos, Harnik, Scott, Eighteen-deoxyaldosterone and other less polar forms of 18-hydroxycorticosterone as aldosterone precursors in rat adrenals (1985) J. steroid Biochem., 22, pp. 665-672
- Bush, Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues (1952) Biochem. J., 50, pp. 370-378
- Bush, Willoughby, The excretion of allotetrahydrocortisol in human urine (1957) Biochem. J., 67, pp. 689-700
- Neher, (1964) Steroid Chromatography, p. 97. , Elsevier, Amsterdam
- Kliman, Peterson, Double isotope derivative assay of aldosterone in biological extracts (1960) J. biol. Chem., 235, pp. 1639-1648
- Aragonés, Gros, Lantos, Locascio, Less polar forms and derivatives of 18-hydroxycorticosterone (1978) J. steroid Biochem., 9, pp. 175-180
- Hampel, Peng, Pearlman, Pearlman, Acylation of [3H]corticosterone by acini from mammary gland of lactating rats (1978) J. biol. Chem., 253, pp. 8545-8553
- Mellon-Nussbaum, Ponticorvo, Lieberman, Characterization of the lipoidal derivatives of pregnenolone prepared by incubation of the steroid with adrenal mitochondria (1979) J. biol. Chem., 254, pp. 12500-12505
- Hochberg, Bandy, Ponticorvo, Lieberman, Detection in bovine adrenal cortex of a lipoidal substance that yields pregnenolone upon treatment with alkali (1977) Proc. natn. Acad. Sci. U.S.A., 74, pp. 941-945
- Mellon-Nussbaum, Hochberg, Biosynthesis of lipoidal derivatives of pregnenolone and dehydroisoandrosterone by the adrenal (1980) J. biol. Chem., 255, pp. 5566-5572
- Genard, Carbon-13 magnetic resonance spectra of aldosterone 18-hydroxycorticosterone and 18-hydroxyprogesterone (1978) Organic Magnetic Resonance, 11, pp. 478-480
- De Vries, De Jong, Chromatographie separation and mass spectrometric behaviour of two isomers of aldosterone (1980) J. steroid Biochem., 13, pp. 387-394
- Damasco, Lantos, The existence of two interconvertible forms of 18-hydroxycorticosterone: is one of them the active precursor of aldosterone? (1975) J. steroid Biochem., 6, pp. 69-74
- Harnik, Kashman, Morris, Synthesis of 3ga, 5α-tetrahydroaldosterone (1984) J. steroid Biochem., 20, pp. 1313-1320
- Lichtwald, Bauer, Soltek, Vecsei, Long known aldosterone derivative. A physiological product? (1984) Seventh International Congress oj Endocrinology, , Excerpta Medica, July 1–7 (1984), Quebec, Canada, Elsevier Science Publishers, Amsterdam, Communication No. 1412
Citas:
---------- APA ----------
Cozza, E.N., Lantos, C.P. & Burton, G.
(1985)
. A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer. Journal of Steroid Biochemistry, 23(4), 511-516.
http://dx.doi.org/10.1016/0022-4731(85)90200-6---------- CHICAGO ----------
Cozza, E.N., Lantos, C.P., Burton, G.
"A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer"
. Journal of Steroid Biochemistry 23, no. 4
(1985) : 511-516.
http://dx.doi.org/10.1016/0022-4731(85)90200-6---------- MLA ----------
Cozza, E.N., Lantos, C.P., Burton, G.
"A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer"
. Journal of Steroid Biochemistry, vol. 23, no. 4, 1985, pp. 511-516.
http://dx.doi.org/10.1016/0022-4731(85)90200-6---------- VANCOUVER ----------
Cozza, E.N., Lantos, C.P., Burton, G. A highly lipophilic form of aldosterone. isolation and characterization of an aldosterone dimer. J. Steroid Biochem. 1985;23(4):511-516.
http://dx.doi.org/10.1016/0022-4731(85)90200-6