The presence of 5-hydroxytryptamine (5-HT) was determined by h.p.l.c. in perchloric extracts of each isolated compartment of the adult rat testis. The testicular capsule, interstitial cells and interstitial fluid contained 5-HT, but 5-HT was not detected in the tubular compartment. In a group of adult rats, one testis was unilaterally denervated, and the contralateral testis used as control. The superior spermatic nerve, arising from the renal plexus, was excised and 1 week after surgery 5-HT content was measured in the capsule and interstitial fluid of both testes. Denervation caused a significant fall (34%) in 5-HT content. These results indicate that at least part of the testicular 5-HT derives from a serotonergic innervation of the gonad.
Documento: | Artículo |
Título: | Serotonergic innervation of the rat testis |
Autor: | Campos, M.B.; Vitale, M.L.; Calandra, R.S.; Chiocchio, S.R. |
Filiación: | Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, Obligado 2490, 1428-Buenos Aires, Argentina |
Palabras clave: | denervation; innervation; interstitial fluid; rat; serotonin; testis; serotonin; article; denervation; innervation; interstitial fluid; male; nonhuman; priority journal; rat; testis |
Año: | 1990 |
Volumen: | 88 |
Número: | 2 |
Página de inicio: | 475 |
Página de fin: | 479 |
DOI: | http://dx.doi.org/10.1530/jrf.0.0880475 |
Título revista: | Journal of Reproduction and Fertility |
Título revista abreviado: | J. REPROD. FERTIL. |
ISSN: | 00224251 |
CODEN: | JRPFA |
CAS: | serotonin, 50-67-9 |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224251_v88_n2_p475_Campos |