The presence of 5-hydroxytryptamine (5-HT) was determined by h.p.l.c. in perchloric extracts of each isolated compartment of the adult rat testis. The testicular capsule, interstitial cells and interstitial fluid contained 5-HT, but 5-HT was not detected in the tubular compartment. In a group of adult rats, one testis was unilaterally denervated, and the contralateral testis used as control. The superior spermatic nerve, arising from the renal plexus, was excised and 1 week after surgery 5-HT content was measured in the capsule and interstitial fluid of both testes. Denervation caused a significant fall (34%) in 5-HT content. These results indicate that at least part of the testicular 5-HT derives from a serotonergic innervation of the gonad.
| Documento: | Artículo |
| Título: | Serotonergic innervation of the rat testis |
| Autor: | Campos, M.B.; Vitale, M.L.; Calandra, R.S.; Chiocchio, S.R. |
| Filiación: | Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, Obligado 2490, 1428-Buenos Aires, Argentina |
| Palabras clave: | denervation; innervation; interstitial fluid; rat; serotonin; testis; serotonin; article; denervation; innervation; interstitial fluid; male; nonhuman; priority journal; rat; testis |
| Año: | 1990 |
| Volumen: | 88 |
| Número: | 2 |
| Página de inicio: | 475 |
| Página de fin: | 479 |
| DOI: | http://dx.doi.org/10.1530/jrf.0.0880475 |
| Título revista: | Journal of Reproduction and Fertility |
| Título revista abreviado: | J. REPROD. FERTIL. |
| ISSN: | 00224251 |
| CODEN: | JRPFA |
| CAS: | serotonin, 50-67-9 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224251_v88_n2_p475_Campos |
