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Abstract:

Ornithine decarboxylase (ODC) activity was measured in epididymides of 45-day-old rats. Higher ODC activity was detected in the corpus and cauda than in the caput epididymidis. Bilateral castration for 7 days caused epididymal ODC to fall to undetectable values, whereas testosterone restored activity to normal values. The effect of the androgen was significantly inhibited by cyproterone acetate. The caput was more sensitive to the action of testosterone than were the corpus and caudal segments. Unilateral castration for 4 or 8 days did not affect ODC on the control or castrated side, but the activity fell in epididymides of both sides after removal of the remaining testis. These results show that epididymal ODC activity is androgen-dependent.

Registro:

Documento: Artículo
Título:Androgen-dependence of ornithine decarboxylase in the rat epididymis
Autor:De Las Heras, M.A.; Calandra, R.S.
Filiación:Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, 1428 Buenos Aires, Argentina
Palabras clave:androgen; cyproterone acetate; ornithine decarboxylase; testosterone; animal cell; castration; endocrine system; epididymis; male genital system; nonhuman; priority journal; rat; Animalia; Caput
Año:1987
Volumen:79
Número:1
Página de inicio:9
Página de fin:14
DOI: http://dx.doi.org/10.1530/jrf.0.0790009
Título revista:Journal of Reproduction and Fertility
Título revista abreviado:J. REPROD. FERTIL.
ISSN:00224251
CODEN:JRPFA
CAS:cyproterone acetate, 427-51-0; ornithine decarboxylase, 9024-60-6; testosterone, 58-22-0
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00224251_v79_n1_p9_DeLasHeras

Citas:

---------- APA ----------
De Las Heras, M.A. & Calandra, R.S. (1987) . Androgen-dependence of ornithine decarboxylase in the rat epididymis. Journal of Reproduction and Fertility, 79(1), 9-14.
http://dx.doi.org/10.1530/jrf.0.0790009
---------- CHICAGO ----------
De Las Heras, M.A., Calandra, R.S. "Androgen-dependence of ornithine decarboxylase in the rat epididymis" . Journal of Reproduction and Fertility 79, no. 1 (1987) : 9-14.
http://dx.doi.org/10.1530/jrf.0.0790009
---------- MLA ----------
De Las Heras, M.A., Calandra, R.S. "Androgen-dependence of ornithine decarboxylase in the rat epididymis" . Journal of Reproduction and Fertility, vol. 79, no. 1, 1987, pp. 9-14.
http://dx.doi.org/10.1530/jrf.0.0790009
---------- VANCOUVER ----------
De Las Heras, M.A., Calandra, R.S. Androgen-dependence of ornithine decarboxylase in the rat epididymis. J. REPROD. FERTIL. 1987;79(1):9-14.
http://dx.doi.org/10.1530/jrf.0.0790009