Artículo
Abstract:
This study examined the prevalence and correlates of pathological affect in Alzheimer's disease. A consecutive series of 103 patients with Alzheimer's disease were examined with a comprehensive psychiatric assessment that included the pathological laughing and crying scale (PLACS). Forty patients (39%) showed pathological affect: 25% showed crying episodes, and 14% showed laughing or mixed (laughing and crying) episodes. Patients with pathological affect crying showed significantly higher depression scores and a significantly higher frequency of major depression and dysthymia than patients with no pathological affect. Patients with mixed pathological affect showed significantly more subcortical atrophy on CT than patients with pathological affect crying. Forty seven per cent of the patients with pathological affect had no congruent mood disorder, and they showed a significantly longer duration of illness and more severe anosognosia than patients with pathological affect that was congruent with an underlying mood disorder. The study validates the PLACS, and shows the high prevalence of pathological affect in Alzheimer's disease.
Registro:
| Documento: | Artículo |
| Título: | Prevalence and clinical correlates of pathological affective display in Alzheimer's disease |
| Autor: | Starkstein, S.E.; Migliorelli, R.; Teson, A.; Petracca, G.; Chemerinsky, E.; Manes, F.; Leiguarda, R. |
| Filiación: | Raul Carres Inst. Neurological Res., Montaneses 2325, 1428 Buenos Aires, Argentina |
| Palabras clave: | Alzheimer's disease; Pathological affective display; Prevalence; affective neurosis; aged; Alzheimer disease; article; brain atrophy; brain cortex; crying; depression; dysthymia; female; human; major clinical study; male; mood; nonverbal communication; priority journal; rating scale |
| Año: | 1995 |
| Volumen: | 59 |
| Número: | 1 |
| Página de inicio: | 55 |
| Página de fin: | 60 |
| DOI: | http://dx.doi.org/10.1136/jnnp.59.1.55 |
| Título revista: | Journal of Neurology Neurosurgery and Psychiatry |
| Título revista abreviado: | J. NEUROL. NEUROSURG. PSYCHIATRY |
| ISSN: | 00223050 |
| CODEN: | JNNPA |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00223050_v59_n1_p55_Starkstein |
Citas:
---------- APA ----------
Starkstein, S.E., Migliorelli, R., Teson, A., Petracca, G., Chemerinsky, E., Manes, F. & Leiguarda, R. (1995) . Prevalence and clinical correlates of pathological affective display in Alzheimer's disease. Journal of Neurology Neurosurgery and Psychiatry, 59(1), 55-60.http://dx.doi.org/10.1136/jnnp.59.1.55
---------- CHICAGO ----------
Starkstein, S.E., Migliorelli, R., Teson, A., Petracca, G., Chemerinsky, E., Manes, F., et al. "Prevalence and clinical correlates of pathological affective display in Alzheimer's disease" . Journal of Neurology Neurosurgery and Psychiatry 59, no. 1 (1995) : 55-60.http://dx.doi.org/10.1136/jnnp.59.1.55
---------- MLA ----------
Starkstein, S.E., Migliorelli, R., Teson, A., Petracca, G., Chemerinsky, E., Manes, F., et al. "Prevalence and clinical correlates of pathological affective display in Alzheimer's disease" . Journal of Neurology Neurosurgery and Psychiatry, vol. 59, no. 1, 1995, pp. 55-60.http://dx.doi.org/10.1136/jnnp.59.1.55
---------- VANCOUVER ----------
Starkstein, S.E., Migliorelli, R., Teson, A., Petracca, G., Chemerinsky, E., Manes, F., et al. Prevalence and clinical correlates of pathological affective display in Alzheimer's disease. J. NEUROL. NEUROSURG. PSYCHIATRY. 1995;59(1):55-60.http://dx.doi.org/10.1136/jnnp.59.1.55
