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Abstract:

Knowledge of the genetic variability, population structure, and evolutionary history of Triatoma infestans may be useful for developing rational vector control strategies. A 661-bp fragment of the mitochondrial gene cytochrome oxidase I (COI) was sequenced and analyzed in bugs from Argentina, Uruguay, Peru, and Bolivia, including peridomestic, domestic, Andean, and Chaco sylvatic bugs. A total of 48 polymorphic sites among 37 haplotypes were described. Nucleotide variation fluctuated among samples, with the highest nucleotide diversity observed in seven Argentinean provinces. Within this group, some populations showed patterns of variability compatible with population expansions and/ or fine-scale population structure, whereas others suggested population bottlenecks and/or population admixture processes. A maximum parsimony analysis of the haplotypes showed the presence of a Bolivian/Peruvian and an Argentinean/Uruguayan clade. Bolivian sequences were further divided in Chaco sylvatic and Andean domestic and sylvatic. Two different nested clades were found within the Argentinean/Uruguayan cluster. Analysis of molecular variance (AMOVA) and K ST analysis supported a strong population structure in Argentina, where genetic differentiation was correlated with geographic distance. Departures from neutrality expectations and a nested cladistic analysis suggest a recent population expansion of T. infestans in Argentina, followed by restricted gene flow and patterns of isolation by distance. This expansion could have taken place as a two-wave process, as was shown by the phylogenetic analysis and signatures of population admixture in the southernmost Argentinean populations. © 2009 Entomological Society of America.

Registro:

Documento: Artículo
Título:Molecular population genetics and phylogeography of the chagas disease vector Triatoma infestans in South America
Autor:Piccinali, R.V.; Marcet, P.L.; Noireau, F.; Kitron, U.; Gürtler, R.E.; Dotson, E.M.
Filiación:Laboratorio de Eco-Epidemiología, Departamento de Ecología, Genética y Evolución, Universidad de Buenos Aires, Ciudad Universitaria, Ciudad Autónoma, Buenos Aires C1428EHA, Argentina
Centers for Disease Control and Prevention, Division of Parasitic Diseases, Entomology Branch, 4770 Buford Highway NE, Chamblee, GA 30341, United States
Departamento de Entomologia, Institute Oswaldo Cruz, Fundação Oswaldo Cruz, Av. Brazil 4365, 21045-900 Rio de Janeiro, Brazil
Institut de Recherche pour le Développement, Unité de Recherche 016, Caractérisation et Contrôle des Populations de Vecteurs, 911 Av. Agropolis, 34394 Montpellier Cedex 5, France
Department of Environmental Studies, Math and Science Center, Emory University, 400 Dowman Dr., Atlanta, GA 30322, United States
Palabras clave:Cytochrome oxidase I; Population admixture; Population expansion; Population structure; Triatoma infestans; animal; article; Chagas disease; disease carrier; genetic variability; genetics; geography; haplotype; human; parasitology; phylogeny; population density; South America; Triatoma; Animals; Chagas Disease; Genetic Variation; Geography; Haplotypes; Humans; Insect Vectors; Phylogeny; Population Density; South America; Triatoma; Triatoma infestans
Año:2009
Volumen:46
Número:4
Página de inicio:796
Página de fin:809
DOI: http://dx.doi.org/10.1603/033.046.0410
Título revista:Journal of Medical Entomology
Título revista abreviado:J. Med. Entomol.
ISSN:00222585
CODEN:JMENA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00222585_v46_n4_p796_Piccinali

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Citas:

---------- APA ----------
Piccinali, R.V., Marcet, P.L., Noireau, F., Kitron, U., Gürtler, R.E. & Dotson, E.M. (2009) . Molecular population genetics and phylogeography of the chagas disease vector Triatoma infestans in South America. Journal of Medical Entomology, 46(4), 796-809.
http://dx.doi.org/10.1603/033.046.0410
---------- CHICAGO ----------
Piccinali, R.V., Marcet, P.L., Noireau, F., Kitron, U., Gürtler, R.E., Dotson, E.M. "Molecular population genetics and phylogeography of the chagas disease vector Triatoma infestans in South America" . Journal of Medical Entomology 46, no. 4 (2009) : 796-809.
http://dx.doi.org/10.1603/033.046.0410
---------- MLA ----------
Piccinali, R.V., Marcet, P.L., Noireau, F., Kitron, U., Gürtler, R.E., Dotson, E.M. "Molecular population genetics and phylogeography of the chagas disease vector Triatoma infestans in South America" . Journal of Medical Entomology, vol. 46, no. 4, 2009, pp. 796-809.
http://dx.doi.org/10.1603/033.046.0410
---------- VANCOUVER ----------
Piccinali, R.V., Marcet, P.L., Noireau, F., Kitron, U., Gürtler, R.E., Dotson, E.M. Molecular population genetics and phylogeography of the chagas disease vector Triatoma infestans in South America. J. Med. Entomol. 2009;46(4):796-809.
http://dx.doi.org/10.1603/033.046.0410