Registro:

Referencias:

• Buckley, C.D., Gilroy, D.W., Serhan, C.N., Stockinger, B., Tak, P.P., The resolution of inflammation (2013) Nat. Rev. Immunol., 13, pp. 59-66
• Serhan, C.N., Pro-resolving lipid mediators are leads for resolution physiology (2014) Nature, 510, pp. 92-101
• Shields, A.M., Panayi, G.S., Corrigall, V.M., Resolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis? (2011) Clin. Exp. Immunol., 165, pp. 292-300
• Méndez-Huergo, S.P., Blidner, A.G., Rabinovich, G.A., Galectins: Emerging regulatory checkpoints linking tumor immunity and angiogenesis (2017) Curr. Opin. Immunol., 45, pp. 8-15
• Sato, S., St-Pierre, C., Bhaumik, P., Nieminen, J., Galectins in innate immunity: Dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs) (2009) Immunol. Rev., 230, pp. 172-187
• Cerliani, J.P., Blidner, A.G., Toscano, M.A., Croci, D.O., Rabinovich, G.A., Translating the ‘sugar code’ into immune and vascular signaling programs (2017) Trends Biochem. Sci., 42, pp. 255-273
• Liu, F.T., Patterson, R.J., Wang, J.L., Intracellular functions of galectins (2002) Biochim. Biophys. Acta, 1572, pp. 263-273
• Rabinovich, G.A., Toscano, M.A., Jackson, S.S., Vasta, G.R., Functions of cell surface galectin-glycoprotein lattices (2007) Curr. Opin. Struct. Biol., 17, pp. 513-520
• Nickel, W., The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes (2003) Eur. J. Biochem., 270, pp. 2109-2119
• Cho, M., Cummings, R.D., Galectin-1, a beta-galactoside-binding lectin in Chinese hamster ovary cells. II. Localization and biosynthesis (1995) J. Biol. Chem., 270, pp. 5207-5212
• Thiemann, S., Baum, L.G., Galectins and immune responses-Just how do they do those things they do? (2016) Annu. Rev. Immunol., 34, pp. 243-264
• Hsu, D.K., Yang, R.Y., Pan, Z., Yu, L., Salomon, D.R., Fung-Leung, W.P., Liu, F.T., Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses (2000) Am. J. Pathol., 156, pp. 1073-1083
• Steichen, A.L., Simonson, T.J., Salmon, S.L., Metzger, D.W., Mishra, B.B., Sharma, J., Alarmin function of galectin-9 in murine respiratory tularemia (2015) PLoS One, 10
• Yip, P.K., Carrillo-Jimenez, A., King, P., Vilalta, A., Nomura, K., Chau, C.C., Egerton, A.M., Tremoleda, J.L., Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration (2017) Sci. Rep., 7, p. 41689
• Kouo, T., Huang, L., Pucsek, A.B., Cao, M., Solt, S., Armstrong, T., Jaffee, E., Galectin-3 shapes antitumor immune responses by suppressing CD8+ T cells via LAG-3 and inhibiting expansion of plasmacytoid dendritic cells (2015) Cancer Immunol. Res., 3, pp. 412-423
• Daley, D., Mani, V.R., Mohan, N., Akkad, N., Ochi, A., Heindel, D.W., Lee, K.B., Savadkar, S., Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance (2017) Nat. Med., 23, pp. 556-567
• Di Lella, S., Sundblad, V., Cerliani, J.P., Guardia, C.M., Estrin, D.A., Vasta, G.R., Rabinovich, G.A., When galectins recognize glycans: From biochemistry to physiology and back again (2011) Biochemistry, 50, pp. 7842-7857
• Stowell, S.R., Cho, M., Feasley, C.L., Arthur, C.M., Song, X., Colucci, J.K., Karmakar, S., Cummings, R.D., Ligand reduces galectin-1 sensitivity to oxidative inactivation by enhancing dimer formation (2009) J. Biol. Chem., 284, pp. 4989-4999
• Croci, D.O., Cerliani, J.P., Dalotto-Moreno, T., Méndez-Huergo, S.P., Mascanfroni, I.D., Dergan-Dylon, S., Toscano, M.A., Ouyang, J., Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors (2014) Cell, 156, pp. 744-758
• De La Fuente, H., Cruz-Adalia, A., Martinez Del Hoyo, G., Cibrián-Vera, D., Bonay, P., Pérez-Hernández, D., Vázquez, J., Ramirez-Huesca, M., The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with galectin-1 (2014) Mol. Cell. Biol., 34, pp. 2479-2487
• Bonzi, J., Bornet, O., Betzi, S., Kasper, B.T., Mahal, L.K., Mancini, S.J., Schiff, C., Elantak, L., Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate affinity to modulate specific galectin-1/glycan lattice interactions (2015) Nat. Commun., 6, p. 6194
• Fuertes, M.B., Molinero, L.L., Toscano, M.A., Ilarregui, J.M., Rubinstein, N., Fainboim, L., Zwirner, N.W., Rabinovich, G.A., Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase (2004) Mol. Cell. Biochem., 267, pp. 177-185
• Zuñiga, E., Rabinovich, G.A., Iglesias, M.M., Gruppi, A., Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis (2001) J. Leukoc. Biol., 70, pp. 73-79
• Rabinovich, G., Castagna, L., Landa, C., Riera, C.M., Sotomayor, C., Regulated expression of a 16-kd galectin-like protein in activated rat macrophages (1996) J. Leukoc. Biol., 59, pp. 363-370
• Garín, M.I., Chu, C.C., Golshayan, D., Cernuda-Morollón, E., Wait, R., Lechler, R.I., Galectin-1: A key effector of regulation mediated by CD4+CD25+ T cells (2007) Blood, 109, pp. 2058-2065
• Dalotto-Moreno, T., Croci, D.O., Cerliani, J.P., Martinez-Allo, V.C., Dergan-Dylon, S., Méndez-Huergo, S.P., Stupirski, J.C., Toscano, M.A., Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease (2013) Cancer Res., 73, pp. 1107-1117
• Ilarregui, J.M., Croci, D.O., Bianco, G.A., Toscano, M.A., Salatino, M., Vermeulen, M.E., Geffner, J.R., Rabinovich, G.A., Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10 (2009) Nat. Immunol., 10, pp. 981-991
• Tesone, A.J., Rutkowski, M.R., Brencicova, E., Svoronos, N., Perales-Puchalt, A., Stephen, T.L., Allegrezza, M.J., Wickramasinghe, J., Satb1 overexpression drives tumor-promoting activities in cancer-associated dendritic cells (2016) Cell Reports, 14, pp. 1774-1786
• Rutkowski, M.R., Stephen, T.L., Svoronos, N., Allegrezza, M.J., Tesone, A.J., Perales-Puchalt, A., Brencicova, E., Cadungog, M.G., Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation (2015) Cancer Cell, 27, pp. 27-40
• Starossom, S.C., Mascanfroni, I.D., Imitola, J., Cao, L., Raddassi, K., Hernandez, S.F., Bassil, R., Delacour, D., Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration (2012) Immunity, 37, pp. 249-263
• Blois, S.M., Ilarregui, J.M., Tometten, M., Garcia, M., Orsal, A.S., Cordo-Russo, R., Toscano, M.A., Handjiski, B., A pivotal role for galectin-1 in fetomaternal tolerance (2007) Nat. Med., 13, pp. 1450-1457
• Ramhorst, R.E., Giribaldi, L., Fraccaroli, L., Toscano, M.A., Stupirski, J.C., Romero, M.D., Durand, E.S., Sedlmayr, P., Galectin-1 confers immune privilege to human trophoblast: Implications in recurrent fetal loss (2012) Glycobiology, 22, pp. 1374-1386
• Dettin, L., Rubinstein, N., Aoki, A., Rabinovich, G.A., Maldonado, C.A., Regulated expression and ultrastructural localization of galectin-1, a pro-apoptotic beta-galactoside-binding lectin, during spermatogenesis in rat testis (2003) Biol. Reprod., 68, pp. 51-59
• Pérez, C.V., Gómez, L.G., Gualdoni, G.S., Lustig, L., Rabinovich, G.A., Guazzone, V.A., Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology (2015) Sci. Rep., 5, p. 12259
• Ridano, M.E., Subirada, P.V., Paz, M.C., Lorenc, V.E., Stupirski, J.C., Gramajo, A.L., Luna, J.D., Sánchez, M.C., Galectin-1 expression imprints a neurovascular phenotype in proliferative retinopathies and delineates responses to anti-VEGF (2017) Oncotarget, 8, pp. 32505-32522
• Suryawanshi, A., Cao, Z., Thitiprasert, T., Zaidi, T.S., Panjwani, N., Galectin-1–mediated suppression of Pseudomonas aeruginosa–induced corneal immunopathology (2013) J. Immunol., 190, pp. 6397-6409
• Poncini, C.V., Ilarregui, J.M., Batalla, E.I., Engels, S., Cerliani, J.P., Cucher, M.A., Van Kooyk, Y., Rabinovich, G.A., Trypanosoma cruzi infection imparts a regulatory program in dendritic cells and T cells via galectin-1–dependent mechanisms (2015) J. Immunol., 195, pp. 3311-3324
• Davicino, R.C., Méndez-Huergo, S.P., Eliçabe, R.J., Stupirski, J.C., Autenrieth, I., Di Genaro, M.S., Rabinovich, G.A., Galectin-1–driven tolerogenic programs aggravate Yersinia enterocolitica infection by repressing antibacterial immunity (2017) J. Immunol., 199, pp. 1382-1392
• Santucci, L., Fiorucci, S., Rubinstein, N., Mencarelli, A., Palazzetti, B., Federici, B., Rabinovich, G.A., Morelli, A., Galectin-1 suppresses experimental colitis in mice (2003) Gastroenterology, 124, pp. 1381-1394
• Ge, X.N., Ha, S.G., Greenberg, Y.G., Rao, A., Bastan, I., Blidner, A.G., Rao, S.P., Sriramarao, P., Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 (2016) Proc. Natl. Acad. Sci. USA, 113, pp. E4837-E4846
• Xie, R.D., Xu, L.Z., Yang, L.T., Wang, S., Liu, Q., Liu, Z.G., Yang, P.C., Galectin-1 inhibits oral-intestinal allergy syndrome (2017) Oncotarget, 8, pp. 13214-13222
• Rubinstein, N., Alvarez, M., Zwirner, N.W., Toscano, M.A., Ilarregui, J.M., Bravo, A., Mordoh, J., Rabinovich, G.A., Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege (2004) Cancer Cell, 5, pp. 241-251
• Croci, D.O., Salatino, M., Rubinstein, N., Cerliani, J.P., Cavallin, L.E., Leung, H.J., Ouyang, J., Domaica, C.I., Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma (2012) J. Exp. Med., 209, pp. 1985-2000
• Martínez-Bosch, N., Fernández-Barrena, M.G., Moreno, M., Ortiz-Zapater, E., Munné-Collado, J., Iglesias, M., André, S., Poirier, F., Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation (2014) Cancer Res., 74, pp. 3512-3524
• Bastón, J.I., Barañao, R.I., Ricci, A.G., Bilotas, M.A., Olivares, C.N., Singla, J.J., Gonzalez, A.M., Meresman, G.F., Targeting galectin-1–induced angiogenesis mitigates the severity of endometriosis (2014) J. Pathol., 234, pp. 329-337
• Blois, S.M., Gueuvoghlanian-Silva, B.Y., Tirado-González, I., Torloni, M.R., Freitag, N., Mattar, R., Conrad, M.L., Knabl, J., Getting too sweet: Galectin-1 dysregulation in gestational diabetes mellitus (2014) Mol. Hum. Reprod., 20, pp. 644-649
• Seropian, I.M., Cerliani, J.P., Toldo, S., Van Tassell, B.W., Ilarregui, J.M., González, G.E., Matoso, M., Gelpi, R.J., Galectin-1 controls cardiac inflammation and ventricular remodeling during acute myocardial infarction (2013) Am. J. Pathol., 182, pp. 29-40
• Medzhitov, R., Origin and physiological roles of inflammation (2008) Nature, 454, pp. 428-435
• Nathan, C., Ding, A., Nonresolving inflammation (2010) Cell, 140, pp. 871-882
• Rabinovich, G.A., Sotomayor, C.E., Riera, C.M., Bianco, I., Correa, S.G., Evidence of a role for galectin-1 in acute inflammation (2000) Eur. J. Immunol., 30, pp. 1331-1339
• La, M., Cao, T.V., Cerchiaro, G., Chilton, K., Hirabayashi, J., Kasai, K., Oliani, S.M., Perretti, M., A novel biological activity for galectin-1: Inhibition of leukocyte-endothelial cell interactions in experimental inflammation (2003) Am. J. Pathol., 163, pp. 1505-1515
• Cooper, D., Norling, L.V., Perretti, M., Novel insights into the inhibitory effects of galectin-1 on neutrophil recruitment under flow (2008) J. Leukoc. Biol., 83, pp. 1459-1466
• Iqbal, A.J., Sampaio, A.L., Maione, F., Greco, K.V., Niki, T., Hirashima, M., Perretti, M., Cooper, D., Endogenous galectin-1 and acute inflammation: Emerging notion of a galectin-9 pro-resolving effect (2011) Am. J. Pathol., 178, pp. 1201-1209
• Stowell, S.R., Karmakar, S., Arthur, C.M., Ju, T., Rodrigues, L.C., Riul, T.B., Dias-Baruffi, M., Cummings, R.D., Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane (2009) Mol. Biol. Cell, 20, pp. 1408-1418
• Auvynet, C., Moreno, S., Melchy, E., Coronado-Martínez, I., Montiel, J.L., Aguilar-Delfin, I., Rosenstein, Y., Galectin-1 promotes human neutrophil migration (2013) Glycobiology, 23, pp. 32-42
• Correa, S.G., Sotomayor, C.E., Aoki, M.P., Maldonado, C.A., Rabinovich, G.A., Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages (2003) Glycobiology, 13, pp. 119-128
• Zúñiga, E., Gruppi, A., Hirabayashi, J., Kasai, K.I., Rabinovich, G.A., Regulated expression and effect of galectin-1 on Trypanosoma cruzi–infected macrophages: Modulation of microbicidal activity and survival (2001) Infect. Immun., 69, pp. 6804-6812
• Barrionuevo, P., Beigier-Bompadre, M., Ilarregui, J.M., Toscano, M.A., Bianco, G.A., Isturiz, M.A., Rabinovich, G.A., A novel function for galectin-1 at the crossroad of innate and adaptive immunity: Galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway (2007) J. Immunol., 178, pp. 436-445
• Rostoker, R., Yaseen, H., Schif-Zuck, S., Lichtenstein, R.G., Rabinovich, G.A., Ariel, A., Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype (2013) Prostaglandins Other Lipid Mediat, 107, pp. 85-94
• Malik, R.K., Ghurye, R.R., Lawrence-Watt, D.J., Stewart, H.J., Galectin-1 stimulates monocyte chemotaxis via the p44/42 MAP kinase pathway and a pertussis toxin-sensitive pathway (2009) Glycobiology, 19, pp. 1402-1407
• Fulcher, J.A., Hashimi, S.T., Levroney, E.L., Pang, M., Gurney, K.B., Baum, L.G., Lee, B., Galectin-1–matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix (2006) J. Immunol., 177, pp. 216-226
• Fulcher, J.A., Chang, M.H., Wang, S., Almazan, T., Hashimi, S.T., Eriksson, A.U., Wen, X., Lee, B., Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling (2009) J. Biol. Chem., 284, pp. 26860-26870
• Thiemann, S., Man, J.H., Chang, M.H., Lee, B., Baum, L.G., Galectin-1 regulates tissue exit of specific dendritic cell populations (2015) J. Biol. Chem., 290, pp. 22662-22677
• Rabinovich, G.A., Ilarregui, J.M., Conveying glycan information into T-cell homeostatic programs: A challenging role for galectin-1 in inflammatory and tumor microenvironments (2009) Immunol. Rev., 230, pp. 144-159
• Stillman, B.N., Hsu, D.K., Pang, M., Brewer, C.F., Johnson, P., Liu, F.T., Baum, L.G., Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death (2006) J. Immunol., 176, pp. 778-789
• Matarrese, P., Tinari, A., Mormone, E., Bianco, G.A., Toscano, M.A., Ascione, B., Rabinovich, G.A., Malorni, W., Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpo-larization, budding, and fission (2005) J. Biol. Chem., 280, pp. 6969-6985
• Deák, M., Hornung, Á., Novák, J., Demydenko, D., Szabó, E., Czibula, Á., Fajka-Boja, R., Kovács, L., Novel role for galectin-1 in T-cells under physiological and pathological conditions (2015) Immunobiology, 220, pp. 483-489
• Stowell, S.R., Karmakar, S., Stowell, C.J., Dias-Baruffi, M., McEver, R.P., Cummings, R.D., Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells (2007) Blood, 109, pp. 219-227
• Banh, A., Zhang, J., Cao, H., Bouley, D.M., Kwok, S., Kong, C., Giaccia, A.J., Le, Q.T., Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis (2011) Cancer Res., 71, pp. 4423-4431
• Toscano, M.A., Bianco, G.A., Ilarregui, J.M., Croci, D.O., Correale, J., Hernandez, J.D., Zwirner, N.W., Rabinovich, G.A., Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death (2007) Nat. Immunol., 8, pp. 825-834
• Salatino, M., Croci, D.O., Bianco, G.A., Ilarregui, J.M., Toscano, M.A., Rabinovich, G.A., Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer (2008) Expert Opin. Biol. Ther., 8, pp. 45-57
• Liu, S.D., Tomassian, T., Bruhn, K.W., Miller, J.F., Poirier, F., Miceli, M.C., Galectin-1 tunes TCR binding and signal transduction to regulate CD8 burst size (2009) J. Immunol., 182, pp. 5283-5295
• Van Der Leij, J., Van Den Berg, A., Blokzijl, T., Harms, G., Van Goor, H., Zwiers, P., Van Weeghel, R., Visser, L., Dimeric galectin-1 induces IL-10 production in T-lymphocytes: An important tool in the regulation of the immune response (2004) J. Pathol., 204, pp. 511-518
• Stowell, S.R., Qian, Y., Karmakar, S., Koyama, N.S., Dias-Baruffi, M., Leffler, H., McEver, R.P., Cummings, R.D., Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion (2008) J. Immunol., 180, pp. 3091-3102
• Cedeno-Laurent, F., Opperman, M., Barthel, S.R., Kuchroo, V.K., Dimitroff, C.J., Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression (2012) J. Immunol., 188, pp. 3127-3137
• Toscano, M.A., Commodaro, A.G., Ilarregui, J.M., Bianco, G.A., Liberman, A., Serra, H.M., Hirabayashi, J., Rabinovich, G.A., Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- And T regulatory-mediated anti-inflammatory responses (2006) J. Immunol., 176, pp. 6323-6332
• Wang, J., Lu, Z.H., Gabius, H.J., Rohowsky-Kochan, C., Ledeen, R.W., Wu, G., Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: Possible role in suppressing experimental autoimmune encephalomyelitis (2009) J. Immunol., 182, pp. 4036-4045
• Gauthier, L., Rossi, B., Roux, F., Termine, E., Schiff, C., Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering (2002) Proc. Natl. Acad. Sci. USA, 99, pp. 13014-13019
• Espeli, M., Mancini, S.J., Breton, C., Poirier, F., Schiff, C., Impaired B-cell development at the pre-BII-cell stage in galectin-1–deficient mice due to inefficient pre-BII/stromal cell interactions (2009) Blood, 113, pp. 5878-5886
• Elantak, L., Espeli, M., Boned, A., Bornet, O., Bonzi, J., Gauthier, L., Feracci, M., Schiff, C., Structural basis for galectin-1–dependent pre-B cell receptor (pre-BCR) activation (2012) J. Biol. Chem., 287, pp. 44703-44713
• Croci, D.O., Morande, P.E., Dergan-Dylon, S., Borge, M., Toscano, M.A., Stupirski, J.C., Bezares, R.F., Gamberale, R., Nurse-like cells control the activity of chronic lymphocytic leukemia B cells via galectin-1 (2013) Leukemia, 27, pp. 1413-1416
• Tsai, C.M., Wu, H.Y., Su, T.H., Kuo, C.W., Huang, H.W., Chung, C.H., Chen, C.S., Lin, K.I., Phosphoproteomic analyses reveal that galectin-1 augments the dynamics of B-cell receptor signaling (2014) J. Proteomics, 103, pp. 241-253
• Tabrizi, S.J., Niiro, H., Masui, M., Yoshimoto, G., Iino, T., Kikushige, Y., Wakasaki, T., Miyamoto, T., T cell leukemia/ lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins (2009) J. Immunol., 182, pp. 1490-1499
• Anginot, A., Espeli, M., Chasson, L., Mancini, S.J., Schiff, C., Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response (2013) J. Immunol., 190, pp. 5526-5533
• Mendez-Huergo, S.P., Maller, S.M., Farez, M.F., Mariño, K., Correale, J., Rabinovich, G.A., Integration of lectin-glycan recognition systems and immune cell networks in CNS inflammation (2014) Cytokine Growth Factor Rev., 25, pp. 247-255
• Offner, H., Celnik, B., Bringman, T.S., Casentini-Borocz, D., Nedwin, G.E., Vandenbark, A.A., Recombinant human beta-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis (1990) J. Neuroimmunol., 28, pp. 177-184
• Mari, E.R., Rasouli, J., Ciric, B., Moore, J.N., Conejo-Garcia, J.R., Rajasagi, N., Zhang, G.X., Rostami, A., Galectin-1 is essential for the induction of MOG35-55–based intravenous tolerance in experimental autoimmune encephalomyelitis (2016) Eur. J. Immunol., 46, pp. 1783-1796
• Rinaldi, M., Thomas, L., Mathieu, P., Carabias, P., Troncoso, M.F., Pasquini, J.M., Rabinovich, G.A., Pasquini, L.A., Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/ phagocytosis and oligodendroglial differentiation (2016) Neurobiol. Dis., 96, pp. 127-143
• Aalinkeel, R., Mangum, C.S., Abou-Jaoude, E., Reynolds, J.L., Liu, M., Sundquist, K., Parikh, N.U., Mahajan, S.D., Galectin-1 reduces neuroinflammation via modulation of nitric oxide-arginase signaling in HIV-1–transfected microglia: A gold nano-particle–galectin-1 “Nanoplex” a possible neurotherapeutic? (2017) J. Neuroimmune Pharmacol., 12, pp. 133-151
• Rabinovich, G.A., Iglesias, M.M., Modesti, N.M., Castagna, L.F., Wolfenstein-Todel, C., Riera, C.M., Sotomayor, C.E., Activated rat macrophages produce a galectin-1–like protein that induces apoptosis of T cells: Biochemical and functional characterization (1998) J. Immunol., 160, pp. 4831-4840
• Rabinovich, G.A., Ariel, A., Hershkoviz, R., Hirabayashi, J., Kasai, K.I., Lider, O., Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1 (1999) Immunology, 97, pp. 100-106
• Rabinovich, G.A., Daly, G., Dreja, H., Tailor, H., Riera, C.M., Hirabayashi, J., Chernajovsky, Y., Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis (1999) J. Exp. Med., 190, pp. 385-398
• Harjacek, M., Diaz-Cano, S., De Miguel, M., Wolfe, H., Maldonado, C.A., Rabinovich, G.A., Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis (2001) J. Rheu-Matol, 28, pp. 1914-1922
• Wang, C.R., Shiau, A.L., Chen, S.Y., Cheng, Z.S., Li, Y.T., Lee, C.H., Yo, Y.T., Juan, H.Y., Intra-articular lentivirus-mediated delivery of galectin-3 shRNA and galectin-1 gene ameliorates collagen-induced arthritis (2010) Gene Ther, 17, pp. 1225-1233
• Filer, A., Bik, M., Parsonage, G.N., Fitton, J., Trebilcock, E., Howlett, K., Cook, M., Thomas, A.M., Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways (2009) Arthritis Rheum, 60, pp. 1604-1614
• Iqbal, A.J., Cooper, D., Vugler, A., Gittens, B.R., Moore, A., Perretti, M., Endogenous galectin-1 exerts tonic inhibition on experimental arthritis (2013) J. Immunol., 191, pp. 171-177
• Zanon, C.De.F., Sonehara, N.M., Girol, A.P., Gil, C.D., Oliani, S.M., Protective effects of the galectin-1 protein on in vivo and in vitro models of ocular inflammation (2015) Mol. Vis., 21, pp. 1036-1050
• Rajasagi, N.K., Suryawanshi, A., Sehrawat, S., Reddy, P.B., Mulik, S., Hirashima, M., Rouse, B.T., Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions (2012) J. Immunol., 188, pp. 4631-4643
• Maldonado, C.A., Castagna, L.F., Rabinovich, G.A., Landa, C.A., Immunocytochemical study of the distribution of a 16-kDa galectin in the chicken retina (1999) Invest. Ophthalmol. Vis. Sci., 40, pp. 2971-2977
• Ishida, K., Panjwani, N., Cao, Z., Streilein, J.W., Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms (2003) Ocul. Immunol. Inflamm., 11, pp. 91-105
• Romero, M.D., Muiño, J.C., Bianco, G.A., Ferrero, M., Juarez, C.P., Luna, J.D., Rabinovich, G.A., Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis (2006) Invest. Ophthalmol. Vis. Sci., 47, pp. 1550-1556
• Gao, J., Wang, X., Wang, Y., Han, F., Cai, W., Zhao, B., Li, Y., Hu, D., Murine Sertoli cells promote the development of tolerogenic dendritic cells: A pivotal role of galectin-1 (2016) Immunology, 148, pp. 253-265
• Perone, M.J., Bertera, S., Shufesky, W.J., Divito, S.J., Montecalvo, A., Mathers, A.R., Larregina, A.T., Wucherpfennig, K.W., Suppression of autoimmune diabetes by soluble galectin-1 (2009) J. Immunol., 182, pp. 2641-2653
• D’Alise, A.M., Auyeung, V., Feuerer, M., Nishio, J., Fontenot, J., Benoist, C., Mathis, D., The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors (2008) Proc. Natl. Acad. Sci. USA, 105, pp. 19857-19862
• Schneider, A., Rieck, M., Sanda, S., Pihoker, C., Greenbaum, C., Buckner, J.H., The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells (2008) J. Immunol., 181, pp. 7350-7355
• Wu, G., Lu, Z.H., Gabius, H.J., Ledeen, R.W., Bleich, D., Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression (2011) Diabetes, 60, pp. 2341-2349
• Motran, C.C., Molinder, K.M., Liu, S.D., Poirier, F., Miceli, M.C., Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function (2008) Eur. J. Immunol., 38, pp. 3015-3027
• Neurath, M.F., Cytokines in inflammatory bowel disease (2014) Nat. Rev. Immunol., 14, pp. 329-342
• Nalle, S.C., Turner, J.R., Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease (2015) Mucosal Immunol., 8, pp. 720-730
• Muller, S., Schaffer, T., Flogerzi, B., Fleetwood, A., Weimann, R., Schoepfer, A.M., Seibold, F., Galectin-3 modulates T cell activity and is reduced in the inflamed intestinal epithelium in IBD (2006) Inflamm. Bowel Dis., 12, pp. 588-597
• Paclik, D., Berndt, U., Guzy, C., Dankof, A., Danese, S., Holzloehner, P., Rosewicz, S., Sturm, A., Galectin-2 induces apoptosis of lamina propria T lymphocytes and ameliorates acute and chronic experimental colitis in mice (2008) J. Mol. Med., 86, pp. 1395-1406. , Berl
• Paclik, D., Danese, S., Berndt, U., Wiedenmann, B., Dignass, A., Sturm, A., Galectin-4 controls intestinal inflammation by selective regulation of peripheral and mucosal T cell apoptosis and cell cycle (2008) PLoS One, 3
• Nishida, A., Nagahama, K., Imaeda, H., Ogawa, A., Lau, C.W., Kobayashi, T., Hisamatsu, T., Ikeuchi, H., Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells (2012) J. Exp. Med., 209, pp. 2383-2394
• Papa Gobbi, R., De Francesco, N., Bondar, C., Muglia, C., Chirdo, F., Rumbo, M., Rocca, A., Docena, G.H., A galectin-specific signature in the gut delineates Crohn’s disease and ulcerative colitis from other human inflammatory intestinal disorders (2016) Biofactors, 42, pp. 93-105
• Muglia, C., Mercer, N., Toscano, M.A., Schattner, M., Pozner, R., Cerliani, J.P., Gobbi, R.P., Docena, G.H., The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine (2011) Cell Death Dis., 2, p. e163
• Muglia, C.I., Gobbi, R.P., Smaldini, P., Delgado, M.L., Candia, M., Zanuzzi, C., Sambuelli, A., Docena, G.H., Inflammation controls sensitivity of human and mouse intestinal epithelial cells to galectin-1 (2016) J. Cell. Physiol., 231, pp. 1575-1585
• Robinson, D., Humbert, M., Buhl, R., Cruz, A.A., Inoue, H., Korom, S., Hanania, N.A., Nair, P., Revisiting type 2-high and type 2-low airway inflammation in asthma: Current knowledge and therapeutic implications (2017) Clin. Exp. Allergy, 47, pp. 161-175
• Norling, L.V., Sampaio, A.L., Cooper, D., Perretti, M., Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking (2008) FASEB J., 22, pp. 682-690
• Sanchez-Cuellar, S., De La Fuente, H., Cruz-Adalia, A., Lamana, A., Cibrian, D., Giron, R.M., Vara, A., Ancochea, J., Reduced expression of galectin-1 and galectin-9 by leucocytes in asthma patients (2012) Clin. Exp. Immunol., 170, pp. 365-374
• Delbrouck, C., Doyen, I., Belot, N., Decaestecker, C., Ghanooni, R., De Lavareille, A., Kaltner, H., Vandenhoven, G., Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration (2002) Lab. Invest., 82, pp. 147-158
• Sena, A.A., Provazzi, P.J., Fernandes, A.M., Cury, P.M., Rahal, P., Oliani, S.M., Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis (2006) Clin. Exp. Allergy, 36, pp. 1260-1267
• Yang, L.T., Shu, Q., Luo, X.Q., Liu, Z.Q., Qiu, S.Q., Liu, J.Q., Guo, H.J., Liu, D.B., Long-term effects: Galectin-1 and specific immunotherapy for allergic responses in the intestine (2017) Allergy
• Blidner, A.G., Rabinovich, G.A., Sweetening’ pregnancy: Galectins at the fetomaternal interface (2013) Am. J. Reprod. Immunol., 69, pp. 369-382
• Tirado-González, I., Freitag, N., Barrientos, G., Shaikly, V., Nagaeva, O., Strand, M., Kjellberg, L., Blois, S.M., Galectin-1 influences trophoblast immune evasion and emerges as a predictive factor for the outcome of pregnancy (2013) Mol. Hum. Reprod., 19, pp. 43-53
• Kopcow, H.D., Rosetti, F., Leung, Y., Allan, D.S., Kutok, J.L., Strominger, J.L., T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1 (2008) Proc. Natl. Acad. Sci. USA, 105, pp. 18472-18477
• Gómez-Chávez, F., Castro-Leyva, V., Espejel-Núñez, A., Zamora-Mendoza, R.G., Rosas-Vargas, H., Cancino-Díaz, J.C., Cancino-Díaz, M.E., Rodríguez-Martínez, S., Galectin-1 reduced the effect of LPS on the IL-6 production in decidual cells by inhibiting LPS on the stimulation of IkBz (2015) J. Reprod. Immunol., 112, pp. 46-52
• Woidacki, K., Popovic, M., Metz, M., Schumacher, A., Linzke, N., Teles, A., Poirier, F., Rabinovich, G.A., Mast cells rescue implantation defects caused by c-kit deficiency (2013) Cell Death Dis, 4, p. e462
• Rabinovich, G.A., Gabrilovich, D., Sotomayor, E.M., Immunosuppressive strategies that are mediated by tumor cells (2007) Annu. Rev. Immunol., 25, pp. 267-296
• Cedeno-Laurent, F., Opperman, M.J., Barthel, S.R., Hays, D., Schatton, T., Zhan, Q., He, X., Frank, M.H., Metabolic inhibition of galectin-1-binding carbohydrates accentuates antitumor immunity (2012) J. Invest. Dermatol., 132, pp. 410-420
• Juszczynski, P., Ouyang, J., Monti, S., Rodig, S.J., Takeyama, K., Abramson, J., Chen, W., Shipp, M.A., The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma (2007) Proc. Natl. Acad. Sci. USA, 104, pp. 13134-13139
• Ouyang, J., Juszczynski, P., Rodig, S.J., Green, M.R., O’Donnell, E., Currie, T., Armant, M., Rabinovich, G.A., Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders (2011) Blood, 117, pp. 4315-4322
• Ito, K., Ralph, S.J., Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8(+) T cells and reduced cancer cell adherence (2012) Clin. Exp. Metastasis, 29, pp. 561-572
• Verschuere, T., Toelen, J., Maes, W., Poirier, F., Boon, L., Tousseyn, T., Mathivet, T., Kiss, R., Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity (2014) Int. J. Cancer, 134, pp. 873-884
• Baker, G.J., Chockley, P., Zamler, D., Castro, M.G., Lowenstein, P.R., Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells (2016) OncoImmunology, 5, p. e1163461
• Soldati, R., Berger, E., Zenclussen, A.C., Jorch, G., Lode, H.N., Salatino, M., Rabinovich, G.A., Fest, S., Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments (2012) Int. J. Cancer, 131, pp. 1131-1141
• Cedeno-Laurent, F., Watanabe, R., Teague, J.E., Kupper, T.S., Clark, R.A., Dimitroff, C.J., Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma (2012) Blood, 119, pp. 3534-3538
• Demotte, N., Stroobant, V., Courtoy, P.J., Van Der Smissen, P., Colau, D., Luescher, I.F., Hivroz, C., Mourad, M., Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes (2008) Immunity, 28, pp. 414-424
• Wu, X., Li, J., Connolly, E.M., Liao, X., Ouyang, J., Giobbie-Hurder, A., Lawrence, D., Zhou, J., Combined Anti-VEGF and Anti–CTLA-4 therapy elicits humoral immunity to galectin-1 which is associated with favorable clinical outcomes (2017) Cancer Immunol. Res., 5, pp. 446-454
• Lykken, J.M., Horikawa, M., Minard-Colin, V., Kamata, M., Miyagaki, T., Poe, J.C., Tedder, T.F., Galectin-1 drives lymphoma CD20 immunotherapy resistance: Validation of a preclinical system to identify resistance mechanisms (2016) Blood, 127, pp. 1886-1895
• Fichorova, R.N., Yamamoto, H.S., Fashemi, T., Foley, E., Ryan, S., Beatty, N., Dawood, H., Singh, B.N., Trichomonas vaginalis lipophosphoglycan exploits binding to galectin-1 and -3 to modulate epithelial immunity (2016) J. Biol. Chem., 291, pp. 998-1013
• Vasta, G.R., Feng, C., González-Montalbán, N., Mancini, J., Yang, L., Abernathy, K., Frost, G., Palm, C., Functions of galectins as ‘self/non-self’-recognition and effector factors (2017) Pathog. Dis
• Cagnoni, A.J., Pérez Sáez, J.M., Rabinovich, G.A., Mariño, K.V., Turning-off signaling by siglecs, selectins, and galectins: Chemical inhibition of glycan-dependent interactions in cancer (2016) Front. Oncol., 6, p. 109

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------