Artículo
Martins Alho, M.A.; Errea, M.I.; Sguerra, V.L.; D'Accorso, N.B.; Talarico, L.B.; García, C.C.; Damonte, E.B. "Synthesis and antiviral evaluation of some carbonucleoside analogues" (2005) Journal of Heterocyclic Chemistry. 42(5):979-983
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Abstract:
1,2-O-Isopropylidene-α-L-threofuranosyl heterocyclic derivatives were synthesized from 1,2-O-isopropylidene-α-D-xilopentadialdo-1,4-furanose and tested for antiviral activity against herpes simplex virus type 1, dengue virus type 2 and Junín virus. For comparative propose, the antiviral activity of some of their pyranosyl analogues were also tested. The furanosyl derivatives showed to be moderate inhibitors of Junin virus and, in general, proved to be more effective than the pyranosyl analogues.
Registro:
| Documento: | Artículo |
| Título: | Synthesis and antiviral evaluation of some carbonucleoside analogues |
| Autor: | Martins Alho, M.A.; Errea, M.I.; Sguerra, V.L.; D'Accorso, N.B.; Talarico, L.B.; García, C.C.; Damonte, E.B. |
| Filiación: | CIHIDECAR (CONICET), Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales Argentina, Argentina Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales Argentina, Argentina |
| Palabras clave: | 1,2 o isopropylidene alpha dextro xylopentadialdo 1,4 furanose; 1,2 o isopropylidene alpha levo furanosyl derivative; antivirus agent; carbonucleoside derivative; heterocyclic compound; nucleoside derivative; pyranosyl derivative; unclassified drug; antiviral activity; article; Dengue virus; drug synthesis; Herpes simplex virus 1; Junin virus; nonhuman |
| Año: | 2005 |
| Volumen: | 42 |
| Número: | 5 |
| Página de inicio: | 979 |
| Página de fin: | 983 |
| Título revista: | Journal of Heterocyclic Chemistry |
| Título revista abreviado: | J. Heterocycl. Chem. |
| ISSN: | 0022152X |
| CODEN: | JHTCA |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho |
Referencias:
- Zhang, H.Y., Yu, H.W., Ma, L.T., Min, J.M., Zhang, L.H., (1998) Tetrahedron Asymmetry, 9, p. 141
- Yu, H.W., Zhang, H.Y., Yang, Z.J., Min, J.M., Ma, L.T., Zhang, L.H., (1998) Pure Appl. Chem., 70, p. 435
- Yang, Z.J., Yu, H.W., Min, J.M., Ma, L.T., Zhang, L.H., (1997) Tetrahedron Asymmetry, 8, p. 2739
- Zhang, M., Zhang, H., Yang, Z., Ma, L., Min, J., Zhang, L., (1999) Carbohydr. Res., 318, p. 157
- Lehman, J., Steck, J., Weiser, W., (1998) Carbohydr. Res., 184, p. 113
- Lehman, J., Sandhoff, K., (1990) Justus Liebigs Ann. Chem., p. 1261
- Casiraghi, G., Cornia, M., Rassu, G., Sante, C.D., Spanu, P., (1992) Tetrahedron, 48, p. 5619
- Damonte, E.B., Junin virus (2002) Wiley Encyclopedia of Molecular Medicine, pp. 1844-1846. , Creighton, T. E., Eds.; John Wiley & Sons, New York
- Martins Alho, M.A., D'Accorso, N.B., (2000) J. Heterocyclic Chem., 37, p. 811
- Seldes, A.M., D'Accorso, N.B., Souto, M.F., Martins Alho, M., Arabehety, C., (2001) J. Mass Spectrom., 36, p. 1069
- Martins Alho, M.A., D'Accorso, N.B., (1999) J. Heterocyclic Chem., 36, p. 177
- McKee, K.T., Huggins, J.W., Trahan, C.J., Mahlandi, B.G., (1988) Antimicrob. Agents Chemother., 32, p. 1304
- Enria, D.A., Maiztegui, J.I., (1994) Antiviral Res., 23, p. 23
- Fascio, M.L., Montesano, V.J., D'Accorso, N.B., (1998) J. Heterocyclic Chem., 35, p. 103. , and references therein
Citas:
---------- APA ----------
Martins Alho, M.A., Errea, M.I., Sguerra, V.L., D'Accorso, N.B., Talarico, L.B., García, C.C. & Damonte, E.B. (2005) . Synthesis and antiviral evaluation of some carbonucleoside analogues. Journal of Heterocyclic Chemistry, 42(5), 979-983.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho [ ]
---------- CHICAGO ----------
Martins Alho, M.A., Errea, M.I., Sguerra, V.L., D'Accorso, N.B., Talarico, L.B., García, C.C., et al. "Synthesis and antiviral evaluation of some carbonucleoside analogues" . Journal of Heterocyclic Chemistry 42, no. 5 (2005) : 979-983.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho [ ]
---------- MLA ----------
Martins Alho, M.A., Errea, M.I., Sguerra, V.L., D'Accorso, N.B., Talarico, L.B., García, C.C., et al. "Synthesis and antiviral evaluation of some carbonucleoside analogues" . Journal of Heterocyclic Chemistry, vol. 42, no. 5, 2005, pp. 979-983.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho [ ]
---------- VANCOUVER ----------
Martins Alho, M.A., Errea, M.I., Sguerra, V.L., D'Accorso, N.B., Talarico, L.B., García, C.C., et al. Synthesis and antiviral evaluation of some carbonucleoside analogues. J. Heterocycl. Chem. 2005;42(5):979-983.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v42_n5_p979_MartinsAlho [ ]
