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Abstract:

A synthetic route to obtain compounds with two different heterocycles, such as isoxazole and tetrazole rings, in the same molecule from carbohydrate derivatives using 1,3-dipolar cycloaddition is described. The new compounds involved in this synthesis are physically and spectroscopically characterized.

Registro:

Documento: Artículo
Título:A synthetic pathway to obtain heterocyclic derivatives containing isoxazole and tetrazole rings joined by a carbohydrate tether
Autor:Martinez Esperón, M.F.; Fascio, M.L.; D'Accorso, N.B.
Filiación:Ctro. de Invest. de Hidra. de Carbo., Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 3 Piso, C. P. 1428 Buenos Aires, Argentina
Palabras clave:3 (dextro xylofuranos 4 yl) 5 phenylisoxazole; 3 (ethyl dextro xylofuranosid 4 yl) 5 phenylisoxazole; carbohydrate; heterocyclic compound; isoxazole derivative; tetrazole derivative; unclassified drug; article; chemical reaction; chemical structure; mass spectrometry; nuclear magnetic resonance spectroscopy; synthesis
Año:2002
Volumen:39
Número:1
Página de inicio:221
Página de fin:224
Título revista:Journal of Heterocyclic Chemistry
Título revista abreviado:J. Heterocycl. Chem.
ISSN:0022152X
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v39_n1_p221_MartinezEsperon

Referencias:

  • (1994) Jpn. Kokai, , Mitsui Toatsu Chemicals, Mitsui Seiyaku Kogyoo KK, Toyama Chemical Co. Ltd.; 06/116146
  • (1994) Chem. Abstr., 121, p. 141722r
  • Marquis, E.T., Sanderson, J.R., US Pat. 52833356 (1994); (1994) Chem. Abstr., 120 (217), p. 649
  • Ermet, P., Vasella, A., (1991) Helv. Chim. Acta., 74, p. 2043
  • Heigthman, T.D., Ermet, P., Vasella, A., Klein, D., (1995) Helv. Chim. Acta., 78, p. 514
  • Davis, B., Brandstetter, T.W., Smith, C., Hackett, L., Winchester, B.G., Fleet, G.W.J., (1995) Tetrahedron Lett., 36, p. 7507
  • Brandstetter, T.W., Davis, B., Smith, C., Hackett, L., Winchester, B.G., Fleet, G.W.J., (1995) Tetrahedron Lett., 36, p. 7511
  • Storr, R.C., (1996) Comprehensive Heterocyclic Chemistry II, 4, pp. 672-678. , R. N. Butler, ed, Pergamon Press, Oxford, and references therein
  • Fascio, M.L., Montesano, V.J., D'Accorso, N.B., (2000) J. Carbohydr. Chem., 19, p. 393
  • Serianni, A.S., Clark, E.L., Barker, R., (1979) Carbohydr. Res., 72, p. 79
  • Ritchie, R.G.S., Cyr, N., Korsch, B., Koch, H.J., Perlin, A.S., (1975) Can. J. Chem., 53, p. 1424
  • D'Accorso, N.B., Thiel, I.M.E., (1987) Carbohydr. Res., 167, p. 301. , and references therein
  • D'Accorso, N.B., Thiel, I.M.E., (1987) Carbohydr. Res., 167, p. 19
  • Martins Alho, M.A., D'Accorso, N.B., (1999) J. Heterocyclic Chem., 36, p. 177. , and references therein
  • Baraldi, P.G., Barco, A., Pollini, G.P., Simoni, D., (1987) Synthesis, p. 857
  • Fascio, L., D'Accorso, N.B., (1995) J. Heterocyclic Chem., 32, p. 816

Citas:

---------- APA ----------
Martinez Esperón, M.F., Fascio, M.L. & D'Accorso, N.B. (2002) . A synthetic pathway to obtain heterocyclic derivatives containing isoxazole and tetrazole rings joined by a carbohydrate tether. Journal of Heterocyclic Chemistry, 39(1), 221-224.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v39_n1_p221_MartinezEsperon [ ]
---------- CHICAGO ----------
Martinez Esperón, M.F., Fascio, M.L., D'Accorso, N.B. "A synthetic pathway to obtain heterocyclic derivatives containing isoxazole and tetrazole rings joined by a carbohydrate tether" . Journal of Heterocyclic Chemistry 39, no. 1 (2002) : 221-224.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v39_n1_p221_MartinezEsperon [ ]
---------- MLA ----------
Martinez Esperón, M.F., Fascio, M.L., D'Accorso, N.B. "A synthetic pathway to obtain heterocyclic derivatives containing isoxazole and tetrazole rings joined by a carbohydrate tether" . Journal of Heterocyclic Chemistry, vol. 39, no. 1, 2002, pp. 221-224.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v39_n1_p221_MartinezEsperon [ ]
---------- VANCOUVER ----------
Martinez Esperón, M.F., Fascio, M.L., D'Accorso, N.B. A synthetic pathway to obtain heterocyclic derivatives containing isoxazole and tetrazole rings joined by a carbohydrate tether. J. Heterocycl. Chem. 2002;39(1):221-224.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v39_n1_p221_MartinezEsperon [ ]