Artículo
Ponce, M.A.; Erra-Balsells, R. "Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids" (2001) Journal of Heterocyclic Chemistry. 38(5):1071-1082
Consulte la política de Acceso Abierto del editor
Abstract:
Nitration of commercial full aromatic β-carboline alkaloids nor-harmane (1), harmane (2), harmine (3), harmol (4), and the 7-acetylated derivative of harmol (5) is described. Advantages and disadvantages of different nitration reagents which involve acidic conditions (HNO3/H+) and neutral conditions (Cu(NO3)2; ceric ammonium nitrate) are discussed. A complete 1H and 13C-nmr characterization including ms and also uv absorption spectra in neutral and acid media is presented. A detailed ei-ms and ld-tof-ms study is enclosed because the nitro-β-carbolines constitute a new family of β-carboline-like chromophores with potential use as matrix in uv-maldi-tof-ms.
Registro:
| Documento: | Artículo |
| Título: | Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids |
| Autor: | Ponce, M.A.; Erra-Balsells, R. |
| Filiación: | Departamento de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 3 Ciudad Universitaria, 1428 Buenos Aires, Argentina |
| Palabras clave: | ammonium nitrate; beta carboline; carboline derivative; carbon 13; copper derivative; harman; harmine; harmol; harmol derivative; unclassified drug; article; drug isolation; drug synthesis; light absorption; nitration; nuclear magnetic resonance spectroscopy; proton nuclear magnetic resonance; reaction analysis; ultraviolet spectroscopy |
| Año: | 2001 |
| Volumen: | 38 |
| Número: | 5 |
| Página de inicio: | 1071 |
| Página de fin: | 1082 |
| DOI: | http://dx.doi.org/10.1002/jhet.5570380510 |
| Título revista: | Journal of Heterocyclic Chemistry |
| Título revista abreviado: | J. Heterocycl. Chem. |
| ISSN: | 0022152X |
| CODEN: | JHTCA |
| CAS: | ammonium nitrate, 6484-52-2; beta carboline, 244-63-3; carbon 13, 14762-74-4; harman, 486-84-0; harmine, 343-27-1, 442-51-3; harmol, 487-03-6 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0022152X_v38_n5_p1071_Ponce |
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Citas:
---------- APA ----------
Ponce, M.A. & Erra-Balsells, R. (2001) . Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids. Journal of Heterocyclic Chemistry, 38(5), 1071-1082.http://dx.doi.org/10.1002/jhet.5570380510
---------- CHICAGO ----------
Ponce, M.A., Erra-Balsells, R. "Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids" . Journal of Heterocyclic Chemistry 38, no. 5 (2001) : 1071-1082.http://dx.doi.org/10.1002/jhet.5570380510
---------- MLA ----------
Ponce, M.A., Erra-Balsells, R. "Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids" . Journal of Heterocyclic Chemistry, vol. 38, no. 5, 2001, pp. 1071-1082.http://dx.doi.org/10.1002/jhet.5570380510
---------- VANCOUVER ----------
Ponce, M.A., Erra-Balsells, R. Synthesis and isolation of nitro-β-carbolines obtained by nitration of commercial β-carboline alkaloids. J. Heterocycl. Chem. 2001;38(5):1071-1082.http://dx.doi.org/10.1002/jhet.5570380510
