Artículo
Ribba, L.; Tamayo, L.; Flores, M.; Riveros, A.; Kogan, M.J.; Cerda, E.; Goyanes, S. "Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications" (2018) Journal of Applied Polymer Science
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Abstract:
A noncytotoxic film was developed in this work with asymmetric biphasic properties (hydrophilic/hydrophobic) that allow for gas exchange. Among its many biomedical applications, it could be applied as a wound dressing material where the absorption of exuded fluids and control of water loss is required simultaneously. Thin meshes were developed modifying one face of poly(lactic acid) (PLA) electrospun mats with polyvinyl alcohol (PVA) using a simple photografting methodology. The contact angle of the modified face of the film was 44° while that of the other face was the original value of 122°. The chemical modification was covalent, as confirmed by X-ray photoelectron spectroscopy, stable over time and resistant to successive washing steps. Cytotoxic assays with fibroblast cells showed that PVA photo-grafted onto PLA meshes present a high cell viability percentage. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47369. © 2019 Wiley Periodicals, Inc.
Registro:
| Documento: | Artículo |
| Título: | Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications |
| Autor: | Ribba, L.; Tamayo, L.; Flores, M.; Riveros, A.; Kogan, M.J.; Cerda, E.; Goyanes, S. |
| Filiación: | Faculty of Sciences, Department of Physics, Laboratory of Polymers and Composite Materials (LP&MC), Buenos Aires Physics Institute (IFIBA-CONICET), Ciudad Universitaria, University of Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina Department of Chemistry, Faculty of Sciences, University of Chile, Las Palmeras 3425, Casilla 653, Santiago, 8320000, Chile Laboratory of surfaces y nanomaterials, Physics Department, Facultad de ciencias físicas y matemáticas, Universidad de Chile, Santiago, Chile Advanced Center for Chronic Diseases, Department of Pharmacological Chemistry and Toxicology, Faculty of Pharmaceutical Sciences, University of Chile, Santos Dumont 964, Box 233, Santiago, Chile Department of Physics, Faculty of Sciences, University of Santiago of Chile, Santiago, Chile |
| Palabras clave: | cytotoxicity; electrospinning mat; wettability; wound dressings; Cell culture; Chemical modification; Contact angle; Cytotoxicity; Grafting (chemical); Hydrophilicity; Lactic acid; Medical applications; Polyvinyl alcohols; Water absorption; Wetting; X ray photoelectron spectroscopy; Biomedical applications; Electrospun mats; Hydrophilic/hydrophobic; Hydrophobic/hydrophilic; Poly (vinyl alcohol) (PVA); Polylactic acids; Wound dressing materials; Wound dressings; Moisture control |
| Año: | 2018 |
| DOI: | http://dx.doi.org/10.1002/app.47369 |
| Título revista: | Journal of Applied Polymer Science |
| Título revista abreviado: | J. Appl. Polym. Sci. |
| ISSN: | 00218995 |
| CODEN: | JAPNA |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00218995_v_n_p_Ribba |
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Citas:
---------- APA ----------
Ribba, L., Tamayo, L., Flores, M., Riveros, A., Kogan, M.J., Cerda, E. & Goyanes, S. (2018) . Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications. Journal of Applied Polymer Science.http://dx.doi.org/10.1002/app.47369
---------- CHICAGO ----------
Ribba, L., Tamayo, L., Flores, M., Riveros, A., Kogan, M.J., Cerda, E., et al. "Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications" . Journal of Applied Polymer Science (2018).http://dx.doi.org/10.1002/app.47369
---------- MLA ----------
Ribba, L., Tamayo, L., Flores, M., Riveros, A., Kogan, M.J., Cerda, E., et al. "Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications" . Journal of Applied Polymer Science, 2018.http://dx.doi.org/10.1002/app.47369
---------- VANCOUVER ----------
Ribba, L., Tamayo, L., Flores, M., Riveros, A., Kogan, M.J., Cerda, E., et al. Asymmetric biphasic hydrophobic/hydrophilic poly(lactic acid)–polyvinyl alcohol meshes with moisture control and noncytotoxic effects for wound dressing applications. J. Appl. Polym. Sci. 2018.http://dx.doi.org/10.1002/app.47369
