Artículo
Abstract:
Spontaneous contractile characteristics as well as inotropic influences of norepinephrine (NE) and prostaglandin E 1 (PGE 1) on different sow oviductal segments isolated from preovulatory or early postovulatory period, were explored. Postovulatory fimbrial preparations contracted with higher intensity and slower frequency the preovulatory ones whereas the spontaneous motility of other regions were comparable at both stages. Norepinephrine (NE) depressed preovulatory ampullar and fimbrio-ampullar portions but stimulated fimbrial and isthmic segments. However, after ovulation NE enhanced the motility of all tubal regions, particularly the fimbrial ones. Phentolamine abolished and even reversed, on postovulatory ampulla, the contractile augmentation elicited by NE. PGE 1 markedly diminished the tension and frequency of preovulatory fimbrial and fimbrio-ampullar segments but it was inactive on other ampullar regions. This depressant influence on the preovulatory fimbrio-ampullar region was replaced, a few hours following ovulation, by a distinct contractile increment. Although phentolamine failed to alter the PGE 1 postovulatory ampullar influences, it clearly blunted the PGE 1 enhancement of postovulatory isthmic motility. The results suggest that changes observed in adrenergic or prostaglandin responses of the sow oviduct may be linked in influences exerted by rapid variations of circulating substances associated with the ovulatory process. Furthermore it is also plausible that the actions of PGE 1 on the isthmus but not on the ampulla is indirect and attributable, at least in part, to the release of NE. It finally appears that the fimbrio-ampullar junction of the domestic sow acts as a 'prostaglandin sphincter' able to avoid the loss of oocytes newly introduced into the oviduct.
Registro:
| Documento: | Artículo |
| Título: | Contractile characteristics of fimbrial, isthmic, ampullar, and fimbrio-ampullar segments of isolated sow (Sus scrofa) oviduct as influenced by ovulation, adrenergic mechanisms, and prostaglandin E 1 |
| Autor: | Borda, E.S.; Speziale, N.B.; Borda, L.J.; Gimeno, M.F.; Gimeno, A.L. |
| Filiación: | Cent. Estudios Farmacol. Principios Naturales, Consejo Nac. Invest. Ci Tecn. Republica Argentina, Buenos Aires 1428, Argentina |
| Palabras clave: | adrenergic receptor; noradrenalin; phentolamine; phentolamine mesylate; prostaglandin e1; animal experiment; drug efficacy; endocrine system; female genital system; in vitro study; ovulation; smooth muscle contractility; swine; uterine tube; Animals; Fallopian Tubes; Female; Norepinephrine; Ovulation; Phentolamine; Prostaglandins E, Synthetic; Swine; Time Factors |
| Año: | 1980 |
| Volumen: | 25 |
| Número: | 1 |
| Página de inicio: | 28 |
| Página de fin: | 35 |
| Título revista: | International Journal of Fertility |
| Título revista abreviado: | INT. J. FERTIL. |
| ISSN: | 0020725X |
| CODEN: | INJFA |
| CAS: | noradrenalin, 1407-84-7, 51-41-2; phentolamine, 50-60-2, 73-05-2; phentolamine mesylate, 65-28-1; prostaglandin E1, 745-65-3; Norepinephrine, 51-41-2; Phentolamine, 50-60-2; Prostaglandins E, Synthetic |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020725X_v25_n1_p28_Borda |
Citas:
---------- APA ----------
Borda, E.S., Speziale, N.B., Borda, L.J., Gimeno, M.F. & Gimeno, A.L. (1980) . Contractile characteristics of fimbrial, isthmic, ampullar, and fimbrio-ampullar segments of isolated sow (Sus scrofa) oviduct as influenced by ovulation, adrenergic mechanisms, and prostaglandin E 1. International Journal of Fertility, 25(1), 28-35.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020725X_v25_n1_p28_Borda [ ]
---------- CHICAGO ----------
Borda, E.S., Speziale, N.B., Borda, L.J., Gimeno, M.F., Gimeno, A.L. "Contractile characteristics of fimbrial, isthmic, ampullar, and fimbrio-ampullar segments of isolated sow (Sus scrofa) oviduct as influenced by ovulation, adrenergic mechanisms, and prostaglandin E 1" . International Journal of Fertility 25, no. 1 (1980) : 28-35.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020725X_v25_n1_p28_Borda [ ]
---------- MLA ----------
Borda, E.S., Speziale, N.B., Borda, L.J., Gimeno, M.F., Gimeno, A.L. "Contractile characteristics of fimbrial, isthmic, ampullar, and fimbrio-ampullar segments of isolated sow (Sus scrofa) oviduct as influenced by ovulation, adrenergic mechanisms, and prostaglandin E 1" . International Journal of Fertility, vol. 25, no. 1, 1980, pp. 28-35.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020725X_v25_n1_p28_Borda [ ]
---------- VANCOUVER ----------
Borda, E.S., Speziale, N.B., Borda, L.J., Gimeno, M.F., Gimeno, A.L. Contractile characteristics of fimbrial, isthmic, ampullar, and fimbrio-ampullar segments of isolated sow (Sus scrofa) oviduct as influenced by ovulation, adrenergic mechanisms, and prostaglandin E 1. INT. J. FERTIL. 1980;25(1):28-35.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020725X_v25_n1_p28_Borda [ ]
