Abstract:
1. 1. PBG-Deaminase obtained from Rp. palustris exhibited classical Michaelis-Menten kinetics in the absence or presence of different ions. 2. 2. Detailed kinetic studies were carried out in the presence of ammonium, phosphate and magnesium ions. 3. 3. It has been found that the different effects observed are dependent on both the substrate and the ion concentration. © 1987.
Registro:
Documento: |
Artículo
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Título: | Porphyrin biosynthesis in Rhodopseudomonas palustris-IX. PBG-deaminase. Kinetic studies |
Autor: | Kotler, M.L.; Fumagalli, S.A.; Juknat, A.A.; Del, A.M.; Batlle, C. |
Filiación: | Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP) (CONICET-Facultad de Ciencias Exactas y Naturales, University of Buenos Aires) Ciudad Universitaria, Pabellón II, 2do. Piso, Buenos Aires, Argentina
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Año: | 1987
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Volumen: | 19
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Número: | 10
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Página de inicio: | 981
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Página de fin: | 985
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DOI: |
http://dx.doi.org/10.1016/0020-711X(87)90181-9 |
Título revista: | International Journal of Biochemistry
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Título revista abreviado: | Int. J. Biochem.
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ISSN: | 0020711X
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CODEN: | IJBOB
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PDF: | https://bibliotecadigital.exactas.uba.ar/download/paper/paper_0020711X_v19_n10_p981_Kotler.pdf |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0020711X_v19_n10_p981_Kotler |
Referencias:
- Anderson, Desnick, Purification and properties of uroporphyrinogen I synthase from human erythrocyte (1980) J. biol. Chem., 255 (5), pp. 1993-1999
- Batlle A.M. del, Rossetti, Enzyme polymerization of porphobilinogen into uroporphyrinogens (1977) Int. J. Biochem., 8, pp. 251-267
- Battersby, Fookes, Hart, Matcham, Pandey, Biosynthesis of porphyrins and related macrocycles Part 21 The interaction of Deaminase and its products (hydroxy-methylbilane) and the relationship between Deaminase and Cosynthetase (1983) Journal of the Chemical Society, Perkin Transactions 1, 1, pp. 3041-3047
- Battersby, Fookes, Matcham, McDonald, Hollenstein, Biosynthesis of porphyrins and related macrocycles Part 20 Purification of deaminase and studies on its mode of action (1983) Journal of the Chemical Society, Perkin Transactions 1, 1, pp. 3031-3040
- Davies, Neuberger, Polypyrroles formed from porphobilinogen and amines by uroporphyrinogen synthetase of Rhodopseudomonas spheroides (1973) Biochem. J., 133, pp. 471-492
- Fumagalli, Kotler, Rossetti, Batlle A.M. del, Human red cell porphobilinogen deaminase. A simpler method of purification and some unusual properties (1985) Int. J. Biochem., 17 (4), pp. 485-494
- Hart, Leeper, Battersby, Modification of hydroxymethylbilane synthase (porphobilinogen deaminase) by pyridoxal 5′-phosphate (1984) Biochem. J., 222, pp. 93-102
- Higuchi, Bogorad, The purification and properties of uroporphyrinogen I synthase and uroporphyrinogen III co-synthetase. Interaction between the enzymes (1975) Ann. N.Y. Acad. Sci., 244, pp. 401-408
- Jordan, Shemin, Purification of uroporphyrinogen I synthetase from Rp spheroides (1973) J Biol Chem, 248, pp. 1019-1024
- Juknat, (1983) Ph.D. thesis, , University of Buenos Aires
- Juknat, Kotler, Batlle A.M. del, (1986) Porphyrin biosynthesis in Rp. palustris IV. Enzymic cyclotetramerization of porphobilinogen into uroporphyrinogens, , In preparation
- Kotler, Fumagalli, Juknat, Batlle A.M. del, Porphyrin biosynthesis in Rp. palustris VIII. Purification and properties of Deaminase (1986) Comp. Biochem. Physiol., B. , In press
- Llambias, Batlle A.M. del, Studies on porphobilinogen deaminase-uroporphyrinogen III cosynthetase system of cultured soyabean cells (1971) Biochem J, 121, pp. 327-340
- Llambias, Batlle A.M. del, Porphyrin biosynthesis VII Avian erythrocyte porphobilinogen deaminase-uroporphyrinogen III cosynthetase its purification properties and the separation of its components (1971) Biochimica et Biophysica Acta (BBA) - Enzymology, 227, pp. 180-191
- Lockwood, Rimington, Purification of an enzyme converting porphobilinogen to uroporphyrinogen (1957) Biochem. J., 67, pp. 8-11
- Miyagi, Kaneshima, Kawakami, Nakada, Petryka, Watson, Uroporphyrinogen I synthase from human erythrocytes: Separation, purification and properties of isoenzymes (1979) Proc. natn. Acad. Sci. U.S.A., 76 (12), pp. 6172-6176
- Moore, Labbe, Assays for ALA and PBG determinations (1964) Clin. Chem., 10, pp. 1105-1109
- Pollack, Russell, Inhibition of wheat germ porphobilinogen deaminase activity by butanediona (1978) FEBS Lett., 90 (1), pp. 47-50
- Rimington, Spectral absorption coefficients of some porphyrins in the Soret band region (1960) Biochem J, 75, pp. 620-623
- Rossetti, (1978) Ph.D. Thesis, , University of Buenos Aires
- Rossetti, Juknat, Kotler, Fumagalli, Batlle A.M. del, Occurrence of multiple molecular forms of porphobilinogenase in diverse organisms: the minimum quaternary structure of porphobilinogenase is a protomer of one deaminase and one isomerase domain (1980) Int. J. Biochem., 12, pp. 761-767
- Sancovich, Batlle A.M. del, Grinstein, The porphobilinogen deaminase-uroporphyrinogen III cosynthetase system (Porphobilinogenase) from bovine liver. Kinetic studies (1969) FEBS Lett., 3 (3), pp. 223-226
- Sancovich, Ferramola, Batlle A.M. del, Grinstein, Preparation of porphobilinogen (1970) Methods in Enzymology, 17, pp. 220-222. , H. Tabor, C.W. Tabor, Academic Press, New York
- Williams, Morgan, McDonald, Battersby, Purification of porphobilinogen deaminase from Euglena gracilis and studies of its kinetics (1981) Biochem. J., 193, pp. 301-310
- Williams, Characterization of the multiple forms of hydroxymethylbilane synthase from rat spleen (1984) Biochem J., 217, pp. 675-683
Citas:
---------- APA ----------
Kotler, M.L., Fumagalli, S.A., Juknat, A.A., Del, A.M. & Batlle, C.
(1987)
. Porphyrin biosynthesis in Rhodopseudomonas palustris-IX. PBG-deaminase. Kinetic studies. International Journal of Biochemistry, 19(10), 981-985.
http://dx.doi.org/10.1016/0020-711X(87)90181-9---------- CHICAGO ----------
Kotler, M.L., Fumagalli, S.A., Juknat, A.A., Del, A.M., Batlle, C.
"Porphyrin biosynthesis in Rhodopseudomonas palustris-IX. PBG-deaminase. Kinetic studies"
. International Journal of Biochemistry 19, no. 10
(1987) : 981-985.
http://dx.doi.org/10.1016/0020-711X(87)90181-9---------- MLA ----------
Kotler, M.L., Fumagalli, S.A., Juknat, A.A., Del, A.M., Batlle, C.
"Porphyrin biosynthesis in Rhodopseudomonas palustris-IX. PBG-deaminase. Kinetic studies"
. International Journal of Biochemistry, vol. 19, no. 10, 1987, pp. 981-985.
http://dx.doi.org/10.1016/0020-711X(87)90181-9---------- VANCOUVER ----------
Kotler, M.L., Fumagalli, S.A., Juknat, A.A., Del, A.M., Batlle, C. Porphyrin biosynthesis in Rhodopseudomonas palustris-IX. PBG-deaminase. Kinetic studies. Int. J. Biochem. 1987;19(10):981-985.
http://dx.doi.org/10.1016/0020-711X(87)90181-9