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Bikiel, D.E.; Solveyra, E.G.; Di Salvo, F.; Milagre, H.M.S.; Eberlin, M.N.; Corrêa, R.S.; Ellena, J.; Estrin, D.A.; Doctorovich, F. "Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand" (2011) Inorganic Chemistry. 50(6):2334-2345
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Abstract:

A new family of compounds is presented as potential carbon monoxide releasing molecules (CORMs). These compounds, based on tetrachlorocarbonyliridate (III) derivatives, were synthesized and fully characterized by X-ray diffraction, electrospray mass spectrometry, IR, NMR, and density functional theory calculations. The rate of CO release was studied via the myoglobin assay. The results showed that the rate depends on the nature of the sixth ligand, trans to CO, and that a significant modulation on the release rate can be produced by changing the ligand. The reported compounds are soluble in aqueous media, and the rates of CO release are comparable with those for known CORMs, releasing CO at a rate of 0.03-0.58 μM min-1 in a 10 μM solution of myoglobin and 10 μM of the complexes. © 2011 American Chemical Society.

Registro:

Documento: Artículo
Título:Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand
Autor:Bikiel, D.E.; Solveyra, E.G.; Di Salvo, F.; Milagre, H.M.S.; Eberlin, M.N.; Corrêa, R.S.; Ellena, J.; Estrin, D.A.; Doctorovich, F.
Filiación:Departamento de Química Inorgánica, Analítica y Química Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, INQUIMAE-CONICET, Ciudad Universitaria, Pabellón II, C1428EHA, Buenos Aires, Argentina
Institute of Biosciences, UNESP-Univ. Estadual Paulista, 13506-900 Rio Claro, SP, Brazil
ThoMSon Mass Spectrometry Laboratory, Institute of Chemistry, University of Campinas, UNICAMP, 13083-970, Campinas SP, Brazil
Departamento de Física e Informática, Instituto de Fisica de São Carlos, Universidad de São Paulo, Caixa Postal 369, São Carlos, SP, CEP 13560-970, Brazil
Palabras clave:carbon monoxide; iridium; ligand; organometallic compound; water; article; chemical structure; chemistry; solubility; synthesis; X ray crystallography; Carbon Monoxide; Crystallography, X-Ray; Iridium; Ligands; Models, Molecular; Organometallic Compounds; Solubility; Water
Año:2011
Volumen:50
Número:6
Página de inicio:2334
Página de fin:2345
DOI: http://dx.doi.org/10.1021/ic102038v
Título revista:Inorganic Chemistry
Título revista abreviado:Inorg. Chem.
ISSN:00201669
CODEN:INOCA
CAS:carbon monoxide, 630-08-0; iridium, 13967-67-4, 7439-88-5; water, 7732-18-5; Carbon Monoxide, 630-08-0; Iridium, 7439-88-5; Ligands; Organometallic Compounds; Water, 7732-18-5
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00201669_v50_n6_p2334_Bikiel

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Citas:

---------- APA ----------
Bikiel, D.E., Solveyra, E.G., Di Salvo, F., Milagre, H.M.S., Eberlin, M.N., Corrêa, R.S., Ellena, J.,..., Doctorovich, F. (2011) . Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand. Inorganic Chemistry, 50(6), 2334-2345.
http://dx.doi.org/10.1021/ic102038v
---------- CHICAGO ----------
Bikiel, D.E., Solveyra, E.G., Di Salvo, F., Milagre, H.M.S., Eberlin, M.N., Corrêa, R.S., et al. "Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand" . Inorganic Chemistry 50, no. 6 (2011) : 2334-2345.
http://dx.doi.org/10.1021/ic102038v
---------- MLA ----------
Bikiel, D.E., Solveyra, E.G., Di Salvo, F., Milagre, H.M.S., Eberlin, M.N., Corrêa, R.S., et al. "Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand" . Inorganic Chemistry, vol. 50, no. 6, 2011, pp. 2334-2345.
http://dx.doi.org/10.1021/ic102038v
---------- VANCOUVER ----------
Bikiel, D.E., Solveyra, E.G., Di Salvo, F., Milagre, H.M.S., Eberlin, M.N., Corrêa, R.S., et al. Tetrachlorocarbonyliridates: Water-soluble carbon monoxide releasing molecules rate-modulated by the sixth ligand. Inorg. Chem. 2011;50(6):2334-2345.
http://dx.doi.org/10.1021/ic102038v