Artículo
Roldan, A.; Castillo, M.B. "Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat" (1984) Hormone and Metabolic Research. 16(1):17-21
Estamos trabajando para incorporar este artículo al repositorio
Consulte la política de Acceso Abierto del editor
Abstract:
Cellular receptors to glucocorticoids and the effect of dexamethasone and corticosterone on 3H-uridine incorporation into the acid-insoluble fraction were studied in thymocytes from adrenalectomized-diabetic rats and adrenalectomized ones. An increase in the dissociation constant of the hormone-receptor plot was observed when adrenalectomized-diabetic animals were compared to adrenalectomized controls. Meanwhile decreasing concentrations of dexamethasone and corticosterone below receptors saturation, were less active as inhibitor of 3H-uridine incorporation into RNA by thymocytes from adrenalectomized-diabetic than from adrenalectomized ones.
Registro:
| Documento: | Artículo |
| Título: | Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat |
| Autor: | Roldan, A.; Castillo, M.B. |
| Filiación: | Instituto de Biologia y Medicina Experimental, 1428 Buenos Aires, Argentina |
| Palabras clave: | corticosterone; dexamethasone; dexamethasone h 3; estradiol; glucocorticoid; progesterone; streptozocin; testosterone; unclassified drug; uridine h 3; adrenalectomy; animal model; article; diabetes mellitus; drug efficacy; endocrine system; nonhuman; rat; thymus; Animalia |
| Año: | 1984 |
| Volumen: | 16 |
| Número: | 1 |
| Página de inicio: | 17 |
| Página de fin: | 21 |
| DOI: | http://dx.doi.org/10.1055/s-2007-1014684 |
| Título revista: | Hormone and Metabolic Research |
| Título revista abreviado: | HORM. METAB. RES. |
| ISSN: | 00185043 |
| CODEN: | HMMRA |
| CAS: | corticosterone, 50-22-6; dexamethasone, 50-02-2; estradiol, 50-28-2; progesterone, 57-83-0; streptozocin, 18883-66-4; testosterone, 58-22-0 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00185043_v16_n1_p17_Roldan |
Citas:
---------- APA ----------
Roldan, A. & Castillo, M.B. (1984) . Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat. Hormone and Metabolic Research, 16(1), 17-21.http://dx.doi.org/10.1055/s-2007-1014684
---------- CHICAGO ----------
Roldan, A., Castillo, M.B. "Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat" . Hormone and Metabolic Research 16, no. 1 (1984) : 17-21.http://dx.doi.org/10.1055/s-2007-1014684
---------- MLA ----------
Roldan, A., Castillo, M.B. "Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat" . Hormone and Metabolic Research, vol. 16, no. 1, 1984, pp. 17-21.http://dx.doi.org/10.1055/s-2007-1014684
---------- VANCOUVER ----------
Roldan, A., Castillo, M.B. Modulation of glucocorticoid effect in thymus of adrenalectomized-diabetic rat. HORM. METAB. RES. 1984;16(1):17-21.http://dx.doi.org/10.1055/s-2007-1014684
