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Abstract:

Studies were carried out on the production of the glucuronide hormone glomerulopressin by the isolated rat liver in male and female rats, and the effect on this production of an inhibitor (Novobiocin) and a stimulator (benzo-(a)pyrene) of glucuronyltransferase activity. It was observed that males produce more glomerulopressin than females, Novobiocin inhibits its production while benzo(a)pyrene enhances it in females but not in males. The changes in glomerulopressin production are related to the changes in glucuronyltransferase activity observed by other authors, suggesting that this enzyme is involved in the production of glomerulopressin.

Registro:

Documento: Artículo
Título:Some factors affecting glomerulopressin production by perfused rat liver
Autor:Arany, E.; Del Castillo, E.; Uranga, J.
Filiación:Inst. Biol. Med. Exp., 1428 Buenos Aires, Argentina
Palabras clave:benzo[a]pyrene; glomerulopressin; glucuronide; glucuronosyltransferase; novobiocin; testosterone propionate; unclassified drug; animal experiment; article; drug efficacy; enzyme activation; liver; nonhuman; sex difference; Animalia
Año:1982
Volumen:14
Número:12
Página de inicio:667
Página de fin:670
DOI: http://dx.doi.org/10.1055/s-2007-1019112
Título revista:Hormone and Metabolic Research
Título revista abreviado:HORM. METAB. RES.
ISSN:00185043
CODEN:HMMRA
CAS:benzo[a]pyrene, 50-32-8; glucuronosyltransferase, 37329-64-9, 9030-08-4; novobiocin, 1476-53-5, 303-81-1, 39301-00-3, 4309-70-0; testosterone propionate, 57-85-2
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00185043_v14_n12_p667_Arany

Citas:

---------- APA ----------
Arany, E., Del Castillo, E. & Uranga, J. (1982) . Some factors affecting glomerulopressin production by perfused rat liver. Hormone and Metabolic Research, 14(12), 667-670.
http://dx.doi.org/10.1055/s-2007-1019112
---------- CHICAGO ----------
Arany, E., Del Castillo, E., Uranga, J. "Some factors affecting glomerulopressin production by perfused rat liver" . Hormone and Metabolic Research 14, no. 12 (1982) : 667-670.
http://dx.doi.org/10.1055/s-2007-1019112
---------- MLA ----------
Arany, E., Del Castillo, E., Uranga, J. "Some factors affecting glomerulopressin production by perfused rat liver" . Hormone and Metabolic Research, vol. 14, no. 12, 1982, pp. 667-670.
http://dx.doi.org/10.1055/s-2007-1019112
---------- VANCOUVER ----------
Arany, E., Del Castillo, E., Uranga, J. Some factors affecting glomerulopressin production by perfused rat liver. HORM. METAB. RES. 1982;14(12):667-670.
http://dx.doi.org/10.1055/s-2007-1019112