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Abstract:

It has long been assumed, since the early works of Mather, that the centromere plays a central role in chiasma position determination, so much so that in all sequential models chiasma determination was supposed to start or finish at this point. More specifically, it has been assumed that the centromere acts as a barrier to the transmission of interference, so that a chiasma in the vicinity of a centromere would not affect the probability of chiasma formation across this point. Some statistical analyses seemed to ratify this supposition. However, a reassessment of the literature led us to the conclusion that the statistical analyses that were not flawed were consistent in showing that interference may act across the centromere. Using large sets of chiasma data from the grasshoppers Leptysma argentina and Chorthippus brunneus and applying statistical approaches that involved either the calculation of coincidence or correlating the distances between the centromere and the nearest chiasma in either arm, it is concluded: 1 that interference acts across the centromere; 2 that the action of interference is not changed by the presence of an intervening centromere.

Registro:

Documento: Artículo
Título:Chiasma interference is blind to centromeres
Autor:Colombo, P.C.; Jones, G.H.
Filiación:Depto. de Cs. Biológicas, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, (1428) Buenos Aires, Argentina
School of Biological Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
Palabras clave:Centromere; Chiasmata; Interference; Orthoptera; animal; article; biological model; centromere; chromosome; genetics; grasshopper; Animals; Centromere; Chromosomes; Grasshoppers; Models, Genetic; Animalia; Chorthippus brunneus; Leptysma; Leptysma argentina; Orthoptera
Año:1997
Volumen:79
Número:2
Página de inicio:214
Página de fin:227
DOI: http://dx.doi.org/10.1038/sj.hdy.6881930
Título revista:Heredity
Título revista abreviado:HEREDITY
ISSN:0018067X
CODEN:HDTYA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0018067X_v79_n2_p214_Colombo

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Citas:

---------- APA ----------
Colombo, P.C. & Jones, G.H. (1997) . Chiasma interference is blind to centromeres. Heredity, 79(2), 214-227.
http://dx.doi.org/10.1038/sj.hdy.6881930
---------- CHICAGO ----------
Colombo, P.C., Jones, G.H. "Chiasma interference is blind to centromeres" . Heredity 79, no. 2 (1997) : 214-227.
http://dx.doi.org/10.1038/sj.hdy.6881930
---------- MLA ----------
Colombo, P.C., Jones, G.H. "Chiasma interference is blind to centromeres" . Heredity, vol. 79, no. 2, 1997, pp. 214-227.
http://dx.doi.org/10.1038/sj.hdy.6881930
---------- VANCOUVER ----------
Colombo, P.C., Jones, G.H. Chiasma interference is blind to centromeres. HEREDITY. 1997;79(2):214-227.
http://dx.doi.org/10.1038/sj.hdy.6881930