Abstract:
A series of acyloxy derivatives of pyridoxine (1) have been prepared by transesterification reactions of 1 and ethyl carboxylates, catalyzed by several lipases. Moreover, acetylated derivatives of 1 were selectively deacetylated by enzymatic catalysis in organic media.
Referencias:
- Zaks, A., Klibanov, A.M., (1985) Proc. Natl. Acad. Sci. U.S.A., 82, p. 3192
- Lay, L., Panza, L., Riva, S., Khitri, M., Tirendi, S., (1996) Carbohydr. Res., 29, p. 197
- Riva, S., (1991) Applied Biocatalysis, , Marcel Dekker, Inc., New York
- Fonteyn, F.M., Blecker, C., Lognoy, G., Marlier, M., Severin, M., (1994) Biotechnol. Lett., 16, p. 693
- Pagani, R., Leoncini, R., Terzuoli, L., Pizzichini, M., Marinello, E., (1994) Biochim. Biophys. Acta, 1204, p. 250
- Fonda, M.L., (1993) Alcohol. Clin. Exp. Res., 17, p. 1171
- Prasad, R., Lakshmi, A.V., Bamji, M.S., (1983) Biochem. Med., 30, p. 333
- Baker, E.M., Canham, J.E., Nuncs, W.T., Sauberlich, H.E., McDowell, M.E., (1964) Am. J. Clin. Nutr., 15, p. 59
- Yang, D., Shih, Y., Liu, H., (1991) J. Org. Chem., 56, p. 2940
- Brown, L., Johnston, G.A., Suckling, C.J., Hailing, P.J., Valivety, R.H., (1993) J. Chem. Soc., Perkin Trans, 1, p. 2777
- Korytnyk, W.J., (1962) Org. Chem., 27, p. 3724
- Korytnyk, W., Wiedeman, W., (1962) J. Chem. Soc., p. 2531
- Baldessari, A., Iglesias, L.E., Gros, E.G., (1992) J. Chem. Res., p. 204
- Baldessari, A., Iglesias, L.E., Gros, E.G., (1993) J. Chem. Res., p. 382
- Baldessari, A., Iglesias, L.E., Gros, E.G., (1994) Biotechnol. Lett., 16, p. 479
- Iglesias, L.E., Baldessari, A., Gros, E.G., (1996) Bioorg. Med. Chem. Lett., 6, p. 853
- Iglesias, L.E., Baldessari, A., Gros, E.G., (1997) Biotechnol. Lett., 20, p. 275
- Iglesias, L.E., Baldessari, A., Gros, E.G., (1998) Anal. Asoc. Quím. Arg., 86, p. 63
- Iglesias, L.E., Baldessari, A., Anal. Asoc. Quim. Arg., , in press
- Baldessari, A., Maier, M.S., Gros, E.G., (1995) Tetrahedron Lett., 36, p. 4349
- Baldessari, A., Bruttomesso, A.C., Gros, E.G., (1996) Helv. Chim. Acta, 79, p. 999
- Testa, E., Fava, F., (1957) Chimia, 11, p. 307
- Korytnyk, W., Paul, W., (1967) J. Org. Chem., 32, p. 3791
- Itiba, A., Miti, K., (1938) Sci. Papers Inst. Phys. Chem. Res., 35, p. 73
- (1965) CA, 63, pp. 587h. , Societé Belge de l'Azote et des Produits Chimiques du Marly, Belg. 640,827, June 5, 1964, Appl. Dec. 5, 1963
- Nakakura, S., (1971) CA, 74, pp. 87855g. , Japan 70 31,666, (Cl. co7cd, A 61K, B01J) Oct. 13, 1970, Appl. Feb. 25, 1967
Citas:
---------- APA ----------
Baldessari, A., Mangone, C.P. & Gros, E.G.
(1998)
. Lipase-catalyzed acylation and deacylation reactions of pyridoxine, a member of vitamin-B6 group. Helvetica Chimica Acta, 81(12), 2407-2413.
http://dx.doi.org/10.1002/(SICI)1522-2675(19981216)81:12<2407::AID-HLCA2407>3.0.CO;2-X---------- CHICAGO ----------
Baldessari, A., Mangone, C.P., Gros, E.G.
"Lipase-catalyzed acylation and deacylation reactions of pyridoxine, a member of vitamin-B6 group"
. Helvetica Chimica Acta 81, no. 12
(1998) : 2407-2413.
http://dx.doi.org/10.1002/(SICI)1522-2675(19981216)81:12<2407::AID-HLCA2407>3.0.CO;2-X---------- MLA ----------
Baldessari, A., Mangone, C.P., Gros, E.G.
"Lipase-catalyzed acylation and deacylation reactions of pyridoxine, a member of vitamin-B6 group"
. Helvetica Chimica Acta, vol. 81, no. 12, 1998, pp. 2407-2413.
http://dx.doi.org/10.1002/(SICI)1522-2675(19981216)81:12<2407::AID-HLCA2407>3.0.CO;2-X---------- VANCOUVER ----------
Baldessari, A., Mangone, C.P., Gros, E.G. Lipase-catalyzed acylation and deacylation reactions of pyridoxine, a member of vitamin-B6 group. Helv. Chim. Acta. 1998;81(12):2407-2413.
http://dx.doi.org/10.1002/(SICI)1522-2675(19981216)81:12<2407::AID-HLCA2407>3.0.CO;2-X