Navegar

Colección

Datos Estadísticas

Artículo

Estamos trabajando para incorporar este artículo al repositorio
Consulte el artículo en la página del editor
Consulte la política de Acceso Abierto del editor

Abstract:

Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). The physicochemical characterization of SBP indicates a Stokes radius of 43.5 Å, a sedimentation coefficient of 5.2 S, and a molecular weight of 93,300. © 1985.

Registro:

Documento: Artículo
Título:Characterization of a sexual steroid binding protein in Bufo arenarum
Autor:Santa-Coloma, T.A.; Fernandez, S.; Charreau, E.H.
Filiación:Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina
Instituto Superior de Investigaciones Biológicas, Tucumán, Argentina
Palabras clave:androstanolone; estradiol; metribolone; sex hormone binding protein; testosterone; endocrine system; female genital system; male genital system; methodology; molecular weight; nonhuman; priority journal; sedimentation coefficient; Animal; Bufo arenarum; Electrophoresis, Polyacrylamide Gel; Estradiol; Kinetics; Sex Hormone-Binding Globulin; Stanolone; Substrate Specificity; Testosterone
Año:1985
Volumen:60
Número:2
Página de inicio:273
Página de fin:279
DOI: http://dx.doi.org/10.1016/0016-6480(85)90324-7
Título revista:General and Comparative Endocrinology
Título revista abreviado:Gen. Comp. Endocrinol.
ISSN:00166480
CODEN:GCENA
CAS:androstanolone, 521-18-6; estradiol, 50-28-2; metribolone, 965-93-5; testosterone, 58-22-0; Estradiol, 50-28-2; Sex Hormone-Binding Globulin; Stanolone, 521-18-6; Testosterone, 57-85-2
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00166480_v60_n2_p273_SantaColoma

Referencias:

  • Ackers, Analytical gel chomatography of proteins (1970) Adv. Protein Chem, 24, pp. 343-446
  • Bardin, Musto, Gunsalus, Kotite, Cheng, Larrea, Becker, Extracellular androgen binding proteins (1981) Annu. Rev. Physiol, 43, pp. 189-198
  • Belgorosky, Rivarola, Sex hormone-binding globulin response to human chorionic gonadotropin stimulation in children with cryptorchidism, anorchia, male pseudo hermaphroditism, and micropenis (1982) J. Clin. Endocrinol. Metab, 54, pp. 698-704
  • Bonne, Raynaud, Methyltrienolone, a specific ligand for cellular androgen receptor (1975) Steroids, 26, pp. 227-232
  • Burns, Rose, Testosterone, estrogen binding protein in sexually mature larvae of Ambystoma tigrinum (1980) Gen. Comp. Endocrinol, 41, pp. 314-320
  • Corvol, Bardin, Species distribution of testosterone-binding globulin (1973) Biol. Reprod, 8, pp. 277-282
  • Davis, Disc electrophoresis. II. Method and application to human serum proteins (1964) Ann. N.Y. Acad. Sci, 121, pp. 404-427
  • Fernandez, Tesone, Miceli, Charreau, (1981) Proceedings, XVII Meeting of the Argentine Society of Biochemical Investigation, , Cordoba, Argentina, Abstract 153
  • Laurent, Killander, A theory of gel filtration and its experimental verification (1964) Journal of Chromatography A, 14, pp. 317-330
  • Martin, Ames, A method for determinating the sedimentation behavior of enzymes: Application to protein mixtures (1961) J. Biol. Chem, 236, pp. 1372-1379
  • Martin, Ozon, Boffa, Liaison des steroides sexuelles aux proteines seriques chez l'Amphibien urodele: Pleurodeles waltii. Influence du sexe (1971) C.R. Acad. Sci. Paris, 272, pp. 1413-1416
  • Martin, Ozon, Steroid protein interaction in nonmammalian vertebrates. II. Steroid binding proteins in the serum of Amphibians: A physiological approach (1975) Biol. Reprod, 13, pp. 371-380
  • Moore, Spielvogel, Zoeller, Wingfield, Testosterone-binding protein in a seasonally breeding amphibian (1983) Gen. Comp. Endocrinol, 49, pp. 15-21
  • Ritzen, French, Weddington, Nayfeh, Hansson, Steroid binding in polyacrylamide gel. Quantitation at steady-state conditions (1974) J. Biol. Chem, 249, pp. 6597-6604
  • Rodbard, Peter, Munson, Thakur, Quantitative characterization of hormone receptors (1980) Cancer, 46, pp. 2907-2918
  • Salhanick, Callard, A sexsteroid binding protein in the plasma of the freshwater turtle, Chrysemys picta (1980) Gen. Comp. Endocrinol, 42, pp. 163-166
  • Schachman, (1959) Ultracentrifugation in Biochemistry, p. 239. , Academic Press, New York
  • Siegel, Monty, Determination of molecular weight and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases (1966) Biochim. Biophys. Acta, 112, pp. 346-362
  • Svedberg, Pedersen, (1940) The Ultracentrifuge, p. 41. , Oxford Univ. Press, London/New York, Johnson Reprint Corporation, New York
  • Tandford, (1961) Physical Chemistry of Macromolecules, p. 356. , Wiley, New York

Citas:

---------- APA ----------
Santa-Coloma, T.A., Fernandez, S. & Charreau, E.H. (1985) . Characterization of a sexual steroid binding protein in Bufo arenarum. General and Comparative Endocrinology, 60(2), 273-279.
http://dx.doi.org/10.1016/0016-6480(85)90324-7
---------- CHICAGO ----------
Santa-Coloma, T.A., Fernandez, S., Charreau, E.H. "Characterization of a sexual steroid binding protein in Bufo arenarum" . General and Comparative Endocrinology 60, no. 2 (1985) : 273-279.
http://dx.doi.org/10.1016/0016-6480(85)90324-7
---------- MLA ----------
Santa-Coloma, T.A., Fernandez, S., Charreau, E.H. "Characterization of a sexual steroid binding protein in Bufo arenarum" . General and Comparative Endocrinology, vol. 60, no. 2, 1985, pp. 273-279.
http://dx.doi.org/10.1016/0016-6480(85)90324-7
---------- VANCOUVER ----------
Santa-Coloma, T.A., Fernandez, S., Charreau, E.H. Characterization of a sexual steroid binding protein in Bufo arenarum. Gen. Comp. Endocrinol. 1985;60(2):273-279.
http://dx.doi.org/10.1016/0016-6480(85)90324-7