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Abstract:

A new member of the ras gene family was characterized from Neurospora crassa cDNA libraries. The clone designated NC-ras codes for a polypeptide containing 213 amino acids (Mr 24000). This polypeptide is 84% homologous to the H-ras-1 domain comprising the first 80 amino acids and 60% homologous to the next 84 residues. The NC-ras polypeptide contains all the well-known sequences involved in the interaction with GTP/GDP, the recognition of the Y13-259 neutralizing antibody, the 'effector site' for interaction with GAP proteins, and the CAAX acylation motif in the COOH-terminal. © 1990.

Registro:

Documento: Artículo
Título:Neurospora crassa cDNA clones coding for a new member of the ras protein family
Autor:Altschuler, D.L.; Muro, A.; Schijman, A.; Almonacid, F.B.; Torres, H.N.
Filiación:Institute de Investigations en Ingenieria Genetica y Biologia Molecular (INGEBI-CONICET), Facultad de Ciencias Exactas y Naturales, Obligado 2490, 1428 Buenos Aires, Argentina
Palabras clave:cDNA; Neurospora crassa; ras-sequence; complementary dna; ras protein; article; dna sequence; fungus; neurospora crassa; nonhuman; priority journal; Amino Acid Sequence; Animal; Base Sequence; Cloning, Molecular; Comparative Study; DNA Probes; DNA, Fungal; Fungal Proteins; Gene Library; Genes, ras; Human; Molecular Sequence Data; Multigene Family; Neurospora crassa; Rats; RNA, Fungal; Sequence Homology, Nucleic Acid; Support, Non-U.S. Gov't; Fungi; Neurospora crassa
Año:1990
Volumen:273
Número:1-2
Página de inicio:103
Página de fin:106
DOI: http://dx.doi.org/10.1016/0014-5793(90)81061-R
Título revista:FEBS Letters
Título revista abreviado:FEBS Lett.
ISSN:00145793
CODEN:FEBLA
CAS:DNA Probes; DNA, Fungal; Fungal Proteins; ras proteins, fungal; RNA, Fungal
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00145793_v273_n1-2_p103_Altschuler

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Citas:

---------- APA ----------
Altschuler, D.L., Muro, A., Schijman, A., Almonacid, F.B. & Torres, H.N. (1990) . Neurospora crassa cDNA clones coding for a new member of the ras protein family. FEBS Letters, 273(1-2), 103-106.
http://dx.doi.org/10.1016/0014-5793(90)81061-R
---------- CHICAGO ----------
Altschuler, D.L., Muro, A., Schijman, A., Almonacid, F.B., Torres, H.N. "Neurospora crassa cDNA clones coding for a new member of the ras protein family" . FEBS Letters 273, no. 1-2 (1990) : 103-106.
http://dx.doi.org/10.1016/0014-5793(90)81061-R
---------- MLA ----------
Altschuler, D.L., Muro, A., Schijman, A., Almonacid, F.B., Torres, H.N. "Neurospora crassa cDNA clones coding for a new member of the ras protein family" . FEBS Letters, vol. 273, no. 1-2, 1990, pp. 103-106.
http://dx.doi.org/10.1016/0014-5793(90)81061-R
---------- VANCOUVER ----------
Altschuler, D.L., Muro, A., Schijman, A., Almonacid, F.B., Torres, H.N. Neurospora crassa cDNA clones coding for a new member of the ras protein family. FEBS Lett. 1990;273(1-2):103-106.
http://dx.doi.org/10.1016/0014-5793(90)81061-R