Abstract:
We have prepared dolichylpyrophosphoryl-[14C]-oligosaccharide (Dol-PP-oligosaccharide) from calf thyroid. Microsomal fractions from human breast tissues catalyzed the transfer of labeled oligosaccharide to endogenous acceptor proteins. Malignant tumors showed higher activity of the oligosaccharide transferring enzyme than normal tissue. With kojibiose (Kj), and inhibitor of (Glc3)-glucosidase, an increase in the radioactivity associated with glycoprotein was observed. © 1985 Birkhäuser Verlag.
Registro:
Documento: |
Artículo
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Título: | Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues |
Autor: | Santa Cruz, A.R.; Baldi, A. |
Filiación: | Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina
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Palabras clave: | human breast cancer glycoproteins; kojibiose; Oligosaccharide transfer; glycoprotein; radioisotope; animal cell; breast; breast cancer; cattle; cow; diagnosis; endocrine system; human; human cell; kojibiose; nonhuman; oligosaccharide transfer; priority journal; thyroid gland; Animal; Breast; Breast Neoplasms; Cattle; Disaccharides; Female; Glycoproteins; Human; Microsomes; Oligosaccharides; Polyisoprenyl Phosphate Sugars; Protein Processing, Post-Translational |
Año: | 1985
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Volumen: | 41
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Número: | 7
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Página de inicio: | 928
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Página de fin: | 929
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DOI: |
http://dx.doi.org/10.1007/BF01970017 |
Título revista: | Experientia
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Título revista abreviado: | Experientia
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ISSN: | 00144754
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CODEN: | EXPEA
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CAS: | Disaccharides; Glycoproteins; kojibiose, 2140-29-6; Oligosaccharides; Polyisoprenyl Phosphate Sugars
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v41_n7_p928_SantaCruz |
Referencias:
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Citas:
---------- APA ----------
Santa Cruz, A.R. & Baldi, A.
(1985)
. Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues. Experientia, 41(7), 928-929.
http://dx.doi.org/10.1007/BF01970017---------- CHICAGO ----------
Santa Cruz, A.R., Baldi, A.
"Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues"
. Experientia 41, no. 7
(1985) : 928-929.
http://dx.doi.org/10.1007/BF01970017---------- MLA ----------
Santa Cruz, A.R., Baldi, A.
"Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues"
. Experientia, vol. 41, no. 7, 1985, pp. 928-929.
http://dx.doi.org/10.1007/BF01970017---------- VANCOUVER ----------
Santa Cruz, A.R., Baldi, A. Transfer of oligosaccharide from oligosaccharide pyrophosphoryl dolichol to endogenous acceptor proteins in human breast malignant and normal tissues. Experientia. 1985;41(7):928-929.
http://dx.doi.org/10.1007/BF01970017