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Abstract:

The effects of thymic cells from alloimmunized mice on the mechanical activity of isolated mouse atria were explored. Immune cells decreased the tension without changing the rate of beating of the atrium. After inhibition of prostaglandin synthesis with indomethacin and acetylsalicylic acid, the negative inotropic action of alloimmunized thymic cells was blocked. © 1983 Birkhäuser Verlag.

Registro:

Documento: Artículo
Título:Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins
Autor:Genaro, A.M.; Cremaschi, G.A.; Sales, M.E.; Borda, E.S.
Filiación:Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Serrano 665/69, Buenos Aires, 1414, Argentina
Palabras clave:acetylsalicylic acid; indometacin; mepyramine; prostaglandin; animal cell; drug efficacy; heart; heart atrium; mouse; nonhuman; Animal; Aspirin; Depression, Chemical; Dose-Response Relationship, Drug; Heart Atrium; Indomethacin; Isoantibodies; Mice; Mice, Inbred BALB C; Myocardial Contraction; Pyrilamine; Support, Non-U.S. Gov't; T-Lymphocytes; Time Factors
Año:1983
Volumen:39
Número:9
Página de inicio:1033
Página de fin:1035
DOI: http://dx.doi.org/10.1007/BF01989789
Título revista:Experientia
Título revista abreviado:Experientia
ISSN:00144754
CODEN:EXPEA
CAS:acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; indometacin, 53-86-1, 74252-25-8, 7681-54-1; mepyramine, 6036-95-9, 91-84-9; Aspirin, 50-78-2; Indomethacin, 53-86-1; Isoantibodies; Pyrilamine, 91-84-9
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v39_n9_p1033_Genaro

Referencias:

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Citas:

---------- APA ----------
Genaro, A.M., Cremaschi, G.A., Sales, M.E. & Borda, E.S. (1983) . Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins. Experientia, 39(9), 1033-1035.
http://dx.doi.org/10.1007/BF01989789
---------- CHICAGO ----------
Genaro, A.M., Cremaschi, G.A., Sales, M.E., Borda, E.S. "Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins" . Experientia 39, no. 9 (1983) : 1033-1035.
http://dx.doi.org/10.1007/BF01989789
---------- MLA ----------
Genaro, A.M., Cremaschi, G.A., Sales, M.E., Borda, E.S. "Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins" . Experientia, vol. 39, no. 9, 1983, pp. 1033-1035.
http://dx.doi.org/10.1007/BF01989789
---------- VANCOUVER ----------
Genaro, A.M., Cremaschi, G.A., Sales, M.E., Borda, E.S. Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins. Experientia. 1983;39(9):1033-1035.
http://dx.doi.org/10.1007/BF01989789