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Abstract:

Na arachidonate (NaA) enhanced the resting basal tone of isolated coronary arteries from diabetic dogs and depressed it in coronary arteries from normal controls. Inhibitors of thromboxane A2 biosynthesis and of lipoxygenases abolished the vasoconstrictor effect of NaA on diabetic arteries, whereas inhibitors of cyclooxygenase activity and PGI2 biosynthesis blocked the vasodilating action of NaA on normal arteries. © 1982 Birkhäuser Verlag.

Registro:

Documento: Artículo
Título:Mechanisms of coronary vasoconstriction induced by Na arachidonate in experimentally diabetic dogs
Autor:Sterin-Borda, L.; Borda, E.; del Castillo, E.J.; Gimeno, M.F.; Gimeno, A.L.
Filiación:Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Serrano 665/69, Buenos Aires, 1414, Argentina
Palabras clave:5,8,11,14 icosatetraynoic acid; acetylsalicylic acid; arachidonic acid; imidazole; indometacin; nordihydroguaiaretic acid; tranylcypromine; animal experiment; cardiovascular system; coronary artery; diabetes mellitus; dog; endocrine system; heart; vasoconstriction; Animals; Arachidonic Acids; Arteries; Coronary Vessels; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Epoprostenol; Lipoxygenase Inhibitors; Pancreatectomy; Thromboxane A2; Vasoconstriction; Animalia; Canis familiaris
Año:1982
Volumen:38
Número:7
Página de inicio:835
Página de fin:837
DOI: http://dx.doi.org/10.1007/BF01972301
Título revista:Experientia
Título revista abreviado:Experientia
ISSN:00144754
CODEN:EXPEA
CAS:5,8,11,14 icosatetraynoic acid, 1191-85-1; acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; arachidonic acid, 506-32-1, 6610-25-9, 7771-44-0; imidazole, 1467-16-9, 288-32-4; indometacin, 53-86-1, 74252-25-8, 7681-54-1; nordihydroguaiaretic acid, 500-38-9; tranylcypromine, 13492-01-8, 155-09-9, 54-97-7; Arachidonic Acids; Cyclooxygenase Inhibitors; Epoprostenol, 35121-78-9; Lipoxygenase Inhibitors; Thromboxane A2, 57576-52-0
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v38_n7_p835_SterinBorda

Referencias:

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Citas:

---------- APA ----------
Sterin-Borda, L., Borda, E., del Castillo, E.J., Gimeno, M.F. & Gimeno, A.L. (1982) . Mechanisms of coronary vasoconstriction induced by Na arachidonate in experimentally diabetic dogs. Experientia, 38(7), 835-837.
http://dx.doi.org/10.1007/BF01972301
---------- CHICAGO ----------
Sterin-Borda, L., Borda, E., del Castillo, E.J., Gimeno, M.F., Gimeno, A.L. "Mechanisms of coronary vasoconstriction induced by Na arachidonate in experimentally diabetic dogs" . Experientia 38, no. 7 (1982) : 835-837.
http://dx.doi.org/10.1007/BF01972301
---------- MLA ----------
Sterin-Borda, L., Borda, E., del Castillo, E.J., Gimeno, M.F., Gimeno, A.L. "Mechanisms of coronary vasoconstriction induced by Na arachidonate in experimentally diabetic dogs" . Experientia, vol. 38, no. 7, 1982, pp. 835-837.
http://dx.doi.org/10.1007/BF01972301
---------- VANCOUVER ----------
Sterin-Borda, L., Borda, E., del Castillo, E.J., Gimeno, M.F., Gimeno, A.L. Mechanisms of coronary vasoconstriction induced by Na arachidonate in experimentally diabetic dogs. Experientia. 1982;38(7):835-837.
http://dx.doi.org/10.1007/BF01972301