Abstract:
The in vivo administration of59Fe to the rat accompanied by acetylsalicylic acid (ASA) enhanced significantly counts in blood, spleen, liver and femur without affecting those of the intestine. The results suggest that ASA augments iron absorption either via an inhibitory action on the synthesis of prostaglandins or by a purely chemical mechanism. © 1981 Birkhäuser Verlag.
Registro:
Documento: |
Artículo
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Título: | Effect of acetylsalicylic acid on iron absorption in the rat |
Autor: | Glikman, P.; Gutnisky, A.; Gimeno, M.F.; Gimeno, A.L. |
Filiación: | Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), V. de Obligado 2490, Buenos Aires, 1428, Argentina Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), V. de Obligado 2490, Buenos Aires, 1428, Argentina
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Palabras clave: | acetylsalicylic acid; iron; iron 59; radioisotope; animal experiment; blood and hemopoietic system; bone; digestive system; drug absorption; drug blood level; drug efficacy; drug interaction; liver; oral drug administration; rat; spleen |
Año: | 1981
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Volumen: | 37
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Número: | 6
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Página de inicio: | 589
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Página de fin: | 590
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DOI: |
http://dx.doi.org/10.1007/BF01990066 |
Título revista: | Experientia
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Título revista abreviado: | Experientia
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ISSN: | 00144754
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CODEN: | EXPEA
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CAS: | acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; iron 59, 14596-12-4; iron, 14093-02-8, 53858-86-9, 7439-89-6
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v37_n6_p589_Glikman |
Referencias:
- Marx, J.J.M., (1979) Blood, 53, p. 204
- El-Shobaki, F.A., Rummel, W., (1977) Res. exp. Med., 171, p. 243
- Layrisse, M., Cook, J.D., Martinez, C., Roche, M., Kuhn, I.N., Walker, R.B., Finch, C.A., (1969) Blood, 33, p. 430
- Torres, Layrisse, M., (1974) Wld Rev. Nutr. Diet., 19, p. 51
- Biroli, Bothwel, T.H., Finch, C.A., (1958) J. Lab. clin. Med., 51, p. 32
- El-Shobaki, F., Rummel, W., (1978) Res. exp. Med., 173, p. 119
- Charlton, R.W., Jacobs, P., Torrance, J.D., Bothwell, T.H., The Role of the Intestinal Mucosa in Iron Absorption* (1965) Journal of Clinical Investigation, 44, p. 543
- Crosby, W.H., (1963) Blood, 22, p. 441
- Conrad, M.E., Crosby, W.H., (1963) Blood, 22, p. 406
- Biroli, Finch, C.A., (1960) J. Lab. clin. Med., 55, p. 216
- Mendel, G., (1961) Blood, 18, p. 727
- Gutnisky, A., Speziale, E., Glikman, P., Gimeno, M.F., Gimeno, A.L., (1980) Acta physiol. latinoam., 30, p. 217
Citas:
---------- APA ----------
Glikman, P., Gutnisky, A., Gimeno, M.F. & Gimeno, A.L.
(1981)
. Effect of acetylsalicylic acid on iron absorption in the rat. Experientia, 37(6), 589-590.
http://dx.doi.org/10.1007/BF01990066---------- CHICAGO ----------
Glikman, P., Gutnisky, A., Gimeno, M.F., Gimeno, A.L.
"Effect of acetylsalicylic acid on iron absorption in the rat"
. Experientia 37, no. 6
(1981) : 589-590.
http://dx.doi.org/10.1007/BF01990066---------- MLA ----------
Glikman, P., Gutnisky, A., Gimeno, M.F., Gimeno, A.L.
"Effect of acetylsalicylic acid on iron absorption in the rat"
. Experientia, vol. 37, no. 6, 1981, pp. 589-590.
http://dx.doi.org/10.1007/BF01990066---------- VANCOUVER ----------
Glikman, P., Gutnisky, A., Gimeno, M.F., Gimeno, A.L. Effect of acetylsalicylic acid on iron absorption in the rat. Experientia. 1981;37(6):589-590.
http://dx.doi.org/10.1007/BF01990066