Treatment of orchidectomized rats with LH, FSH or prolactin decreased the tubulin content of the medial basal hypothalamus (MBH), whereas FSH or prolactin augmented it in the adenohypophysis (AH). After castration, negative correlations existed between serum LH and total or polymerized MBH tubulin, whereas in the AH positive correlations were found. After estradiol-progesterone treatment of spayed rats a significant correlation was found between serum LH and the percentage of AH tubulin in the polymerized form. © 1980 Birkhäuser Verlag.
Documento: | Artículo |
Título: | Changes in total and polymerized tubulin of the medial basal hypothalamus and adenohypophysis of castrated or hormone-injected rats |
Autor: | Valenti, C.E.; Lombardo, R.J.; Libertun, C.; Cardinali, D.P. |
Filiación: | Centro de Estudios Farmacológicos y de Principios Naturales, and Instituto de Biología y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina |
Palabras clave: | follitropin; luteinizing hormone; prolactin; tubulin; animal experiment; endocrine system; etiology; hypothalamus; male genital system; nervous system; orchiectomy; rat; theoretical study; Animal; Castration; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Hypothalamus; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Prolactin; Rats; Support, Non-U.S. Gov't; Testosterone; Tubulin |
Año: | 1980 |
Volumen: | 36 |
Número: | 8 |
Página de inicio: | 1012 |
Página de fin: | 1014 |
DOI: | http://dx.doi.org/10.1007/BF01953854 |
Título revista: | Experientia |
Título revista abreviado: | Experientia |
ISSN: | 00144754 |
CODEN: | EXPEA |
CAS: | follitropin, 9002-68-0; luteinizing hormone, 39341-83-8, 9002-67-9; prolactin, 12585-34-1, 50647-00-2, 9002-62-4; Follicle Stimulating Hormone, 9002-68-0; Gonadotropins, Pituitary; Luteinizing Hormone, 9002-67-9; Prolactin, 9002-62-4; Testosterone, 57-85-2; Tubulin |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v36_n8_p1012_Valenti |