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Abstract:

In diabetic rats,3H-estradiol binding by the cytosol and nuclei of the anterior pituitary was lower than normal. Changes in affinity and receptor numbers were demonstrated by Scatchard analysis. Protein synthesis in diabetic pituitaries, however, was in the normal range. © 1980 Birkhäuser Verlag.

Registro:

Documento: Artículo
Título:Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats
Autor:Coirini, H.; Weisenberg, L.; Tornello, S.; De Nicola, A.F.
Filiación:Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina
Palabras clave:drug receptor; radioisotope; sex hormone binding protein; adenohypophysis; amino acid c 14; animal experiment; cell nucleus; central nervous system; cytosol; diabetes mellitus; endocrine system; estradiol h 3; hypophysis; hypothalamus; ovariectomy; protein synthesis; rat; Animal; Castration; Cell Nucleus; Comparative Study; Cytosol; Diabetes Mellitus, Experimental; Estradiol; Female; Hypothalamus; Ovary; Pituitary Gland, Anterior; Rats; Receptors, Estrogen
Año:1980
Volumen:36
Número:6
Página de inicio:683
Página de fin:685
DOI: http://dx.doi.org/10.1007/BF01970139
Título revista:Experientia
Título revista abreviado:Experientia
ISSN:00144754
CODEN:EXPEA
CAS:Estradiol, 50-28-2; Receptors, Estrogen
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v36_n6_p683_Coirini

Referencias:

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  • L. Weisenberg, A.F. De Nicola, M.C. Arakelian and C. Libertun, Endocrinology, in press (1980); Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., (1951) J. biol. Chem., 193, p. 265
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Citas:

---------- APA ----------
Coirini, H., Weisenberg, L., Tornello, S. & De Nicola, A.F. (1980) . Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats. Experientia, 36(6), 683-685.
http://dx.doi.org/10.1007/BF01970139
---------- CHICAGO ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F. "Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats" . Experientia 36, no. 6 (1980) : 683-685.
http://dx.doi.org/10.1007/BF01970139
---------- MLA ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F. "Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats" . Experientia, vol. 36, no. 6, 1980, pp. 683-685.
http://dx.doi.org/10.1007/BF01970139
---------- VANCOUVER ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F. Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats. Experientia. 1980;36(6):683-685.
http://dx.doi.org/10.1007/BF01970139