Abstract:
In diabetic rats,3H-estradiol binding by the cytosol and nuclei of the anterior pituitary was lower than normal. Changes in affinity and receptor numbers were demonstrated by Scatchard analysis. Protein synthesis in diabetic pituitaries, however, was in the normal range. © 1980 Birkhäuser Verlag.
Registro:
Documento: |
Artículo
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Título: | Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats |
Autor: | Coirini, H.; Weisenberg, L.; Tornello, S.; De Nicola, A.F. |
Filiación: | Laboratorio de Esteroides, Instituto de Biologia y Medicina Experimental, Obligado 2490, Buenos Aires, 1428, Argentina
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Palabras clave: | drug receptor; radioisotope; sex hormone binding protein; adenohypophysis; amino acid c 14; animal experiment; cell nucleus; central nervous system; cytosol; diabetes mellitus; endocrine system; estradiol h 3; hypophysis; hypothalamus; ovariectomy; protein synthesis; rat; Animal; Castration; Cell Nucleus; Comparative Study; Cytosol; Diabetes Mellitus, Experimental; Estradiol; Female; Hypothalamus; Ovary; Pituitary Gland, Anterior; Rats; Receptors, Estrogen |
Año: | 1980
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Volumen: | 36
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Número: | 6
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Página de inicio: | 683
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Página de fin: | 685
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DOI: |
http://dx.doi.org/10.1007/BF01970139 |
Título revista: | Experientia
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Título revista abreviado: | Experientia
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ISSN: | 00144754
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CODEN: | EXPEA
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CAS: | Estradiol, 50-28-2; Receptors, Estrogen
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v36_n6_p683_Coirini |
Referencias:
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- Shipley, E.G., Danley, K.S., Pituitary and ovarian dysfunction in experimental diabetes. (1947) Am J Physiol, 150, p. 84
- Foglia, V.G., Borghelli, R.F., Chieri, R.A., Fernández Collazo, E.L., Spindler, I., Wesely, O., (1963) Diabetes, 12, p. 231
- Liu, F.T.Y., Lin, H.S., Johnson, D.C., (1972) Endocrinology, 91, p. 1172
- Denari, J.H., Rosner, J., (1972) Steroids Lipids Res., 3, p. 151
- Gentry, R.T., Wade, G.N., Blaustein, J.D., (1977) Brain Res., 135, p. 135
- Junod, A., Lambert, A.E., Orci, L., Pictet, R., Gonet, A.E., Renold, A.E., (1967) Proc. Soc. exp. Biol. Med., 126, p. 201
- L. Weisenberg, A.F. De Nicola, M.C. Arakelian and C. Libertun, Endocrinology, in press (1980); Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., (1951) J. biol. Chem., 193, p. 265
- Fridman, O., Foglia, V.G., De Nicola, A.F., (1978) J. Steroid Biochem., 9, p. 609
- B.S. McEwen and R.E. Zigmond, in: Methods in Neurochemistry, 1972; Mc Clusky, N.J., Chaptal, C., Lieberburg, I., McEwen, B.S., (1976) Brain Res., 114, p. 158
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- Clark, J.H., Peck, E.J., (1976) Nature, 260, p. 635
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- Kirchick, H.J., Keyes, P.L., Frye, B.E., (1978) Endocrinology, 102, p. 1867
- De Nicola, A.F., Fridman, O., Del Castillo, E.J., Foglia, V.G., (1977) Horm. Metab. Res., 9, p. 469
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Citas:
---------- APA ----------
Coirini, H., Weisenberg, L., Tornello, S. & De Nicola, A.F.
(1980)
. Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats. Experientia, 36(6), 683-685.
http://dx.doi.org/10.1007/BF01970139---------- CHICAGO ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F.
"Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats"
. Experientia 36, no. 6
(1980) : 683-685.
http://dx.doi.org/10.1007/BF01970139---------- MLA ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F.
"Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats"
. Experientia, vol. 36, no. 6, 1980, pp. 683-685.
http://dx.doi.org/10.1007/BF01970139---------- VANCOUVER ----------
Coirini, H., Weisenberg, L., Tornello, S., De Nicola, A.F. Effect of experimental diabetes on estradiol binding by the anterior pituitary and hypothalamus in ovariectomized rats. Experientia. 1980;36(6):683-685.
http://dx.doi.org/10.1007/BF01970139