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Abstract:

The electrically-induced mechanical activity of isolated segments of rat sciatic nerves remains unaffected following incubation with 10-4 M colchicine, vinblastine or melatonin. Vinblastine depressed tubulin levels in incubated nerves. These results suggest that microtubules are not involved in nerve mechanical activity in vitro. © 1980 Birkhäuser Verlag.

Registro:

Documento: Artículo
Título:Is tubulin involved in the electrically-induced mechanical activity of the isolated rat sciatic nerve?
Autor:Valenti, C.E.; de Gimeno, M.F.; Cardinali, D.P.; Gimeno, A.L.
Filiación:Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Obligado 2490, Buenos Aires, 1428, Argentina
Palabras clave:colchicine; melatonin; tubulin; vinblastine; animal experiment; in vitro study; kidney tubule; nerve contraction; nerve stimulation; nervous system; peripheral nervous system; rat; sciatic nerve; Animal; Colchicine; Electric Stimulation; Melatonin; Rats; Sciatic Nerve; Tubulin; Vinblastine
Año:1980
Volumen:36
Número:4
Página de inicio:425
Página de fin:427
DOI: http://dx.doi.org/10.1007/BF01975126
Título revista:Experientia
Título revista abreviado:Experientia
ISSN:00144754
CODEN:EXPEA
CAS:colchicine, 64-86-8; melatonin, 73-31-4; vinblastine, 865-21-4; Colchicine, 64-86-8; Melatonin, 73-31-4; Tubulin; Vinblastine, 865-21-4
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00144754_v36_n4_p425_Valenti

Referencias:

  • da Silva, M.C., Gimeno, M.F., Gimeno, A.L., (1977) Experientia, 33, p. 481
  • Shelanski, M.L., (1974) Research Methods in Neurochemistry, vol. 2, , N., Marks, R., Rodnight, Plenum Press, New York
  • S. Ochs, in: Proceedings of the 6th International Congress of Pharmacology, vol. 2, p. 161. Ed. J. Tumitso, M.K. Paasomen and L. Ahtee. Helsinky 1975; Saon, F.E., (1976) A. Rev. Pharmac. Tox., 16, p. 143
  • Valenti, C.E., Vacas, M.I., Cardinali, D.P., (1979) Experientia, 35, p. 120
  • Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., (1971) J. biol. Chem., 193, p. 265
  • Li, C.C., (1964) Introduction to Experimental Statistics, , McGraw Hill, New York
  • Shelanski, M.L., (1973) Endocrinology, , R.O., Scow, P.J.G., Ebling, J.W., Henderson, Excerpta, Amsterdam
  • Wilson, L., Bamburg, J.R., Mizel, S.B., Grisham, L.M., Creswell, K.M., (1974) Fedn Proc., 33, p. 151
  • Snyder, J., McIntosh, R., (1976) A. Rev. Biochem., 45, p. 699
  • Cardinali, D.P., Freire, F., (1975) Molec. cell. Endocr., 2, p. 317
  • Prevedello, M.R., Ritta, M.N., Cardinali, D.P., (1979) Neurosci. Lett., 13, p. 29
  • Trifaro, J.M., (1978) Neurosciences, 3, p. 1

Citas:

---------- APA ----------
Valenti, C.E., de Gimeno, M.F., Cardinali, D.P. & Gimeno, A.L. (1980) . Is tubulin involved in the electrically-induced mechanical activity of the isolated rat sciatic nerve?. Experientia, 36(4), 425-427.
http://dx.doi.org/10.1007/BF01975126
---------- CHICAGO ----------
Valenti, C.E., de Gimeno, M.F., Cardinali, D.P., Gimeno, A.L. "Is tubulin involved in the electrically-induced mechanical activity of the isolated rat sciatic nerve?" . Experientia 36, no. 4 (1980) : 425-427.
http://dx.doi.org/10.1007/BF01975126
---------- MLA ----------
Valenti, C.E., de Gimeno, M.F., Cardinali, D.P., Gimeno, A.L. "Is tubulin involved in the electrically-induced mechanical activity of the isolated rat sciatic nerve?" . Experientia, vol. 36, no. 4, 1980, pp. 425-427.
http://dx.doi.org/10.1007/BF01975126
---------- VANCOUVER ----------
Valenti, C.E., de Gimeno, M.F., Cardinali, D.P., Gimeno, A.L. Is tubulin involved in the electrically-induced mechanical activity of the isolated rat sciatic nerve?. Experientia. 1980;36(4):425-427.
http://dx.doi.org/10.1007/BF01975126