Artículo
Cardinali, D.P.; Ritta, M.N.; Fuentes, A.M.; Gimeno, M.F.; Gimeno, A.L. "Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations" (1980) European Journal of Pharmacology. 67(1):151-153
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Abstract:
Melatonin depressed PGE release by rat medial basal hypothalamus (MBH) in vitro at concentrations 10−8 M or greater. The two-fold increase in PGE release induced by adding 10−4 M norepinephrine to MBH explants was also impaired by melatonin at micromolar or greater concentrations. These data support the view that melatonin is a physiological inhibitor of PG synthesis in MBH. © 1980, All rights reserved.
Registro:
| Documento: | Artículo |
| Título: | Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations |
| Autor: | Cardinali, D.P.; Ritta, M.N.; Fuentes, A.M.; Gimeno, M.F.; Gimeno, A.L. |
| Filiación: | Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), V. de Obligado 2490, Buenos Aires, 1428, Argentina |
| Palabras clave: | Medial basal hypothalamus; Melatonin; Prostaglandins; melatonin; prostaglandin E; animal; article; drug effect; hypothalamus; in vitro study; male; metabolism; rat; Animals; Hypothalamus; Hypothalamus, Middle; Male; Melatonin; Prostaglandins E; Rats |
| Año: | 1980 |
| Volumen: | 67 |
| Número: | 1 |
| Página de inicio: | 151 |
| Página de fin: | 153 |
| DOI: | http://dx.doi.org/10.1016/0014-2999(80)90025-4 |
| Título revista: | European Journal of Pharmacology |
| Título revista abreviado: | Eur. J. Pharmacol. |
| ISSN: | 00142999 |
| CAS: | melatonin, 73-31-4; prostaglandin E, 11042-70-9; Melatonin, 73-31-4; Prostaglandins E |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142999_v67_n1_p151_Cardinali |
Referencias:
- Cardinali, D.P., Gómez, E., Changes in hypothalamic noradrenaline, dopamine and serotonin uptake after oestradiol administration to rats (1977) J. Endocrinol., 73, p. 181
- Cardinali, D.P., Vacas, M.I., Boyer, E.E., Specific binding of melatonin in bovine brain (1979) Endocrinology, 105, p. 437
- Gimeno, M.F., Landa, A., Speziale, N.S., Cardinali, D.P., Gimeno, A.L., Melatonin blocks in vitro generation of prostaglandin by the uterus and hypothalamus (1980) European J. Pharmacol., 69, p. 309
- Maclouf, J., Andrieu, J.M., Oray, F., Validity of PGE radioimmunoassay by using PGE antisera with differential binding parameters (1975) FEBS Lett., 56, p. 273
- Moguilevsky, J.A., Faigón, M.R., Scacchi, P., Cardinali, D.P., Effect of melatonin and superior cervical ganglionectomy on luteinizing hormone release induced by estradiol-progesterone in castrated rats (1979) Neuroendocrinology, 29, p. 163
- Ojeda, S.R., Negro-Vilar, A., Mc Cann, S.M., Release of prostaglandin Es by hypothalamic tissue: evidence for their involvement in catecholamine-induced luteinizing hormone-releasing hormone release (1979) Endocrinology, 104, p. 617
- Vacas, M.I., Cardinali, D.P., Diurnal changes in melatonin binding sites of hamster and rat brains. Correlation with neuroendocrine responsiveness to melatonin (1979) Neurosci. Lett., 15, p. 259
Citas:
---------- APA ----------
Cardinali, D.P., Ritta, M.N., Fuentes, A.M., Gimeno, M.F. & Gimeno, A.L. (1980) . Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations. European Journal of Pharmacology, 67(1), 151-153.http://dx.doi.org/10.1016/0014-2999(80)90025-4
---------- CHICAGO ----------
Cardinali, D.P., Ritta, M.N., Fuentes, A.M., Gimeno, M.F., Gimeno, A.L. "Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations" . European Journal of Pharmacology 67, no. 1 (1980) : 151-153.http://dx.doi.org/10.1016/0014-2999(80)90025-4
---------- MLA ----------
Cardinali, D.P., Ritta, M.N., Fuentes, A.M., Gimeno, M.F., Gimeno, A.L. "Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations" . European Journal of Pharmacology, vol. 67, no. 1, 1980, pp. 151-153.http://dx.doi.org/10.1016/0014-2999(80)90025-4
---------- VANCOUVER ----------
Cardinali, D.P., Ritta, M.N., Fuentes, A.M., Gimeno, M.F., Gimeno, A.L. Prostaglandin E release by rat medial basal hypothalamus in vitro. Inhibition by melatonin at submicromolar concentrations. Eur. J. Pharmacol. 1980;67(1):151-153.http://dx.doi.org/10.1016/0014-2999(80)90025-4
