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Abstract:

The synthesis by yeast microsomes of compounds that are probably dolichol‐pyrophosphate derivatives containing N,N′‐diacetylchitobiose and several mannose residues is described. However, the presence of monosaccharide residues other than N‐acetylglucosamine and mannose has not been ruled out. The amount of the lipid derivatives synthesized was enhanced by the addition to the incubation mixture of an organic‐solvent‐soluble extract from rat liver known to contain dolichol‐pyrophosphate oligosaccharides. Incubation of these derivatives with yeast microsomes led to the transfer of about fifteen percent of their saccharide moieties to endogenous proteins. The oligosaccharides released from the dolichol derivatives by mild acid hydrolysis could serve as primers for the synthesis of a polysaccharide having the characteristics of mannan outer‐chain. It is suggested that the dolichol‐pyrophosphate derivatives described in this paper are intermediates in the synthesis of mannan inner core. Copyright © 1978, Wiley Blackwell. All rights reserved

Registro:

Documento: Artículo
Título:Lipid Intermediates in the Synthesis of the Inner Core of Yeast Mannan
Autor:PARODI, A.J.
Filiación:Instituto de Investigaciones Bioquímicas 'Fundación Campomar', Obligado 2490, Buenos Aires, RA-1428, Argentina
Palabras clave:lipid; mannan; mannose; n acetylglucosamine; animal experiment; cell wall; fungus; microsome; n,n' diacetylchitobiose; saccharomyces cerevisiae; theoretical study; Carbohydrates; Dolichol Phosphates; Kinetics; Mannans; Oligosaccharides; Polyisoprenyl Phosphates; Polysaccharides; Saccharomyces cerevisiae
Año:1978
Volumen:83
Número:1
Página de inicio:253
Página de fin:259
DOI: http://dx.doi.org/10.1111/j.1432-1033.1978.tb12090.x
Título revista:European Journal of Biochemistry
Título revista abreviado:Eur. J. Biochem.
ISSN:00142956
CAS:lipid, 66455-18-3; mannan, 51395-96-1, 9036-88-8; mannose, 31103-86-3, 3458-28-4; n acetylglucosamine, 7512-17-6; Carbohydrates; Dolichol Phosphates; Mannans; Oligosaccharides; Polyisoprenyl Phosphates; Polysaccharides
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v83_n1_p253_PARODI

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Citas:

---------- APA ----------
(1978) . Lipid Intermediates in the Synthesis of the Inner Core of Yeast Mannan. European Journal of Biochemistry, 83(1), 253-259.
http://dx.doi.org/10.1111/j.1432-1033.1978.tb12090.x
---------- CHICAGO ----------
PARODI, A.J. "Lipid Intermediates in the Synthesis of the Inner Core of Yeast Mannan" . European Journal of Biochemistry 83, no. 1 (1978) : 253-259.
http://dx.doi.org/10.1111/j.1432-1033.1978.tb12090.x
---------- MLA ----------
PARODI, A.J. "Lipid Intermediates in the Synthesis of the Inner Core of Yeast Mannan" . European Journal of Biochemistry, vol. 83, no. 1, 1978, pp. 253-259.
http://dx.doi.org/10.1111/j.1432-1033.1978.tb12090.x
---------- VANCOUVER ----------
PARODI, A.J. Lipid Intermediates in the Synthesis of the Inner Core of Yeast Mannan. Eur. J. Biochem. 1978;83(1):253-259.
http://dx.doi.org/10.1111/j.1432-1033.1978.tb12090.x