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Abstract:

Lipopeptidophosphoglycan, extracted from whole cells of epimastigote forms of Trypanosoma cruzi, has now been shown to contain 12.6% of fatty acids in addition to the previously identified content of neutral sugars (60%), glucosamine (0.8%), peptide (9.5%) and acid‐hydrolyzable phosphate (2%). The main fatty acids are palmitic (6.9%) and lignoceric (4.6%) acids. Stearic (0.55%), oleic (0.15%) and myristic (0.18%) acids were also found. One third of the fatty acids are bound in the lipopeptidophosphoglycan as esters (14 mmol%) and two thirds as amides (28 mmol%). Lignoceric acid was found to be bound only as amide. Two ninhydrin‐positive compounds, obtained by chloroform extraction of a total acid hydrolysate of the lipopeptidophosphoglycan, were tentatively identified as sphingosine bases. Copyright © 1977, Wiley Blackwell. All rights reserved

Registro:

Documento: Artículo
Título:Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids
Autor:DE LEDERKREMER, R.M.; TANAKA, C.T.; ALVES, M.J.M.; COLLI, W.
Filiación:Departamento de Quimica Organica, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aim, Ciudad Universitaria, Nufiez, Buenos Aires, Argentina
Departamento de Bioquimica, Instituto de Quimica, Universidade de Sào Paulo, Cidade Universitària, Caixa postal 20.780, Säo Paulo, Brazil
Palabras clave:amide; carbohydrate; drug derivative; fatty acid; hydroxylamine; organophosphorus compound; peptidoglycan; phospholipid; fatty acid; glucosamine; lignoceric acid; myristic acid; palmitic acid; peptidoglycan; phospholipid; sphingosine; stearic acid; animal; article; gas chromatography; isolation and purification; polyacrylamide gel electrophoresis; Trypanosoma cruzi; cell membrane; glycan phosphate lipoprotein; in vitro study; microorganism; theoretical study; trypanosoma cruzi; Amides; Animal; Carbohydrates; Chromatography, Gas; Electrophoresis, Polyacrylamide Gel; Fatty Acids; Hydroxylamines; Organophosphorus Compounds; Peptidoglycan; Phospholipids; Trypanosoma cruzi
Año:1977
Volumen:74
Número:2
Página de inicio:263
Página de fin:267
DOI: http://dx.doi.org/10.1111/j.1432-1033.1977.tb11389.x
Título revista:European Journal of Biochemistry
Título revista abreviado:Eur. J. Biochem.
ISSN:00142956
CAS:amide, 17655-31-1; hydroxylamine, 7803-49-8; peptidoglycan, 9047-10-3; glucosamine, 3416-24-8, 4607-22-1; lignoceric acid, 557-59-5; myristic acid, 1715-79-3, 544-63-8; palmitic acid, 57-10-3; sphingosine, 123-78-4; stearic acid, 57-11-4, 646-29-7; Amides; Carbohydrates; Fatty Acids; Hydroxylamines; Organophosphorus Compounds; Peptidoglycan; Phospholipids
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00142956_v74_n2_p263_DELEDERKREMER

Referencias:

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Citas:

---------- APA ----------
DE LEDERKREMER, R.M., TANAKA, C.T., ALVES, M.J.M. & COLLI, W. (1977) . Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids. European Journal of Biochemistry, 74(2), 263-267.
http://dx.doi.org/10.1111/j.1432-1033.1977.tb11389.x
---------- CHICAGO ----------
DE LEDERKREMER, R.M., TANAKA, C.T., ALVES, M.J.M., COLLI, W. "Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids" . European Journal of Biochemistry 74, no. 2 (1977) : 263-267.
http://dx.doi.org/10.1111/j.1432-1033.1977.tb11389.x
---------- MLA ----------
DE LEDERKREMER, R.M., TANAKA, C.T., ALVES, M.J.M., COLLI, W. "Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids" . European Journal of Biochemistry, vol. 74, no. 2, 1977, pp. 263-267.
http://dx.doi.org/10.1111/j.1432-1033.1977.tb11389.x
---------- VANCOUVER ----------
DE LEDERKREMER, R.M., TANAKA, C.T., ALVES, M.J.M., COLLI, W. Lipopeptidophosphoglycan from Trypanosoma cruzi Amide and Ester‐Linked Fatty Acids. Eur. J. Biochem. 1977;74(2):263-267.
http://dx.doi.org/10.1111/j.1432-1033.1977.tb11389.x