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Abstract:

Background. Procalcitonin (PCT) is widely accepted as an early marker of the severity of sepsis and its prognosis. This study was designed to evaluate the utility of PCT in the early diagnosis of immediate postoperative complications (infectious and non-infectious) following cephalic pancreatoduodenectomy (PD). Patients and method. Thirty-one patients who underwent elective PD were prospectively analyzed. The patients were divided into two groups according to the presence or absence of postoperative complications. Plasma PCT concentrations were determined by an immunochromatographic method. The correlation between PCT concentrations and the presence of complications, as well as the existence of statistically significant differences in PCT concentrations between the 2 groups of patients, were analyzed. The value of plasma PCT concentrations in predicting complications compared with that of other biochemical variables (C-reactive protein, lactic acid, base excess) and clinical parameters (systemic inflammatory response syndrome) was analyzed. Results. Significant differences in PCT concentrations were found between the two groups. An inverse correlation between marker levels and patient outcome was observed. The variables that best predicted the development of complications were PCT concentrations and axillary temperature. Conclusions. Plasma PCT should be taken into account as a useful marker for postoperative clinical course in the follow-up of PD and for the early detection of non-infectious complications.

Registro:

Documento: Artículo
Título:Role of plasma procalcitonin determination in the postoperative follow-up of cephalic pancreatoduodenectomy
Autor:Bianchi, R.A.; Haedo, A.S.; Romero, M.C.
Filiación:Servicio de Cirugía General, Hospital General de Agudos Dr. Cosme Argerich, Ciudad Autonoma de Buenos Aires, Argentina
Departamento de Computación, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
Departamento de Química Biológica, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina
Laboratorio Central, Hospital General de Agudos Dr. Cosme Argerich, Ciudad Autonoma de Buenos Aires, Argentina
Laboratorio de Análisis Biológicos, Departamento de Química Biológica, Universidad de Buenos Aires, (C1428EHA) Cd. Autonoma Buenos Aires, Argentina
Palabras clave:Pancreatoduodenectomy; Postoperative outcome; Procalcitonin; calcitonin; procalcitonin; protein precursor; adult; aged; article; blood; female; follow up; human; male; methodology; middle aged; pancreaticoduodenectomy; postoperative care; postoperative complication; prediction and forecasting; preoperative care; prospective study; sepsis; Adult; Aged; Calcitonin; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pancreaticoduodenectomy; Postoperative Care; Postoperative Complications; Predictive Value of Tests; Preoperative Care; Prospective Studies; Protein Precursors; Sepsis
Año:2006
Volumen:79
Número:6
Página de inicio:356
Página de fin:360
DOI: http://dx.doi.org/10.1016/S0009-739X(06)70890-9
Título revista:Cirugia Espanola
Título revista abreviado:Cir. Esp.
ISSN:0009739X
CODEN:CRESA
CAS:calcitonin, 12321-44-7, 21215-62-3, 9007-12-9; procalcitonin, 56645-65-9; Calcitonin, 9007-12-9; Protein Precursors; procalcitonin, 56645-65-9
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0009739X_v79_n6_p356_Bianchi

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Citas:

---------- APA ----------
Bianchi, R.A., Haedo, A.S. & Romero, M.C. (2006) . Role of plasma procalcitonin determination in the postoperative follow-up of cephalic pancreatoduodenectomy . Cirugia Espanola, 79(6), 356-360.
http://dx.doi.org/10.1016/S0009-739X(06)70890-9
---------- CHICAGO ----------
Bianchi, R.A., Haedo, A.S., Romero, M.C. "Role of plasma procalcitonin determination in the postoperative follow-up of cephalic pancreatoduodenectomy " . Cirugia Espanola 79, no. 6 (2006) : 356-360.
http://dx.doi.org/10.1016/S0009-739X(06)70890-9
---------- MLA ----------
Bianchi, R.A., Haedo, A.S., Romero, M.C. "Role of plasma procalcitonin determination in the postoperative follow-up of cephalic pancreatoduodenectomy " . Cirugia Espanola, vol. 79, no. 6, 2006, pp. 356-360.
http://dx.doi.org/10.1016/S0009-739X(06)70890-9
---------- VANCOUVER ----------
Bianchi, R.A., Haedo, A.S., Romero, M.C. Role of plasma procalcitonin determination in the postoperative follow-up of cephalic pancreatoduodenectomy . Cir. Esp. 2006;79(6):356-360.
http://dx.doi.org/10.1016/S0009-739X(06)70890-9