Abstract:
Pterins belong to a family of heterocyclic compounds present in a wide range of living systems and participate in relevant biological functions. Under anaerobic conditions, the unstable red intermediate generated by UV-A irradiation of biopterin, neopterin and 6-hydroxymethylpterin was identified by 1H NMR analysis, in alkaline D2O solutions, as 5,8-dihydro-6-formylpterin. © 2009 Elsevier B.V. All rights reserved.
Registro:
Documento: |
Artículo
|
Título: | 1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions |
Autor: | Vignoni, M.; Salum, M.L.; Erra-Balsells, R.; Thomas, A.H.; Cabrerizo, F.M. |
Filiación: | INIFTA, Departamento de Química, Facultad de Ciencias Exactas, Casilla de Correo 16, Sucursal 4, 1900 La Plata, Argentina CIHIDECAR - CONICET, Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Pabellon 2, 3p, Ciudad Universitaria, 1428 Buenos Aires, Argentina
|
Palabras clave: | Anaerobic conditions; Aqueous solutions; Biological functions; Biopterin; Heterocyclic compound; Living systems; Neopterin; NMR analysis; Nuclear magnetic resonance |
Año: | 2010
|
Volumen: | 484
|
Número: | 4-6
|
Página de inicio: | 330
|
Página de fin: | 332
|
DOI: |
http://dx.doi.org/10.1016/j.cplett.2009.12.008 |
Título revista: | Chemical Physics Letters
|
Título revista abreviado: | Chem. Phys. Lett.
|
ISSN: | 00092614
|
CODEN: | CHPLB
|
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00092614_v484_n4-6_p330_Vignoni |
Referencias:
- Nichol, C.A., Smith, G.K., Duch, D.S., (1985) Annu. Rev. Biochem., 54, p. 729
- Hevel, J.M., Marietta, M.A., (1992) Biochemistry, 31, p. 7160
- Huber, C., Batchelor, J.R., Fuchs, D., (1984) J. Exp. Med., 160, p. 310
- Fuchs, D., Hausen, A., Reibnegger, G., Werner, E.R., Dierich, M.P., Wachter, H., (1988) Immunol. Today, 9, p. 150
- Schallreuter, K.U., (1994) Science, 263, p. 1444
- Rokos, H., Beazley, W.D., Schallreuter, K.U., (2002) Biochem. Biophys. Res. Commun., 292, p. 805
- Forrest, H.S., Mitchell, H.K., (1955) J. Am. Chem. Soc., 77, p. 4865
- Viscontini, M., Raschig, H., (1958) Helv. Chim. Acta, 41, p. 108
- Mengel, R., Pfleiderer, W., Knappe, W.R., (1977) Tetrahedron Lett., 18, p. 2817
- Baur, R., Kappel, M., Mengel, R., Pfleiderer, W., (1979) Chemistry and Biology of Pteridines, , Elsevier/North-Holland, New York
- Vignoni, M., Cabrerizo, F.M., Lorente, C., Thomas, A.H., (2009) Photochem. Photobiol., 85, p. 365
- Cabrerizo, F.M., Thomas, A.H., Lorente, C., Dántola, M.L., Petroselli, G., Erra-Balsells, R., Capparelli, A.L., (2004) Helv. Chim. Acta, 87, p. 349
- Thomas, A.H., Cabrerizo, R., Vignoni, M., Erra-Balsells, R., Cabrerizo, F.M., Capparelli, A.L., (2006) Helv. Chim. Acta, 89, p. 1090
Citas:
---------- APA ----------
Vignoni, M., Salum, M.L., Erra-Balsells, R., Thomas, A.H. & Cabrerizo, F.M.
(2010)
. 1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions. Chemical Physics Letters, 484(4-6), 330-332.
http://dx.doi.org/10.1016/j.cplett.2009.12.008---------- CHICAGO ----------
Vignoni, M., Salum, M.L., Erra-Balsells, R., Thomas, A.H., Cabrerizo, F.M.
"1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions"
. Chemical Physics Letters 484, no. 4-6
(2010) : 330-332.
http://dx.doi.org/10.1016/j.cplett.2009.12.008---------- MLA ----------
Vignoni, M., Salum, M.L., Erra-Balsells, R., Thomas, A.H., Cabrerizo, F.M.
"1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions"
. Chemical Physics Letters, vol. 484, no. 4-6, 2010, pp. 330-332.
http://dx.doi.org/10.1016/j.cplett.2009.12.008---------- VANCOUVER ----------
Vignoni, M., Salum, M.L., Erra-Balsells, R., Thomas, A.H., Cabrerizo, F.M. 1H NMR characterization of the intermediate formed upon UV-A excitation of biopterin, neopterin and 6-hydroxymethylpterin in O2-free aqueous solutions. Chem. Phys. Lett. 2010;484(4-6):330-332.
http://dx.doi.org/10.1016/j.cplett.2009.12.008