Abstract:
Peracylated glycofuranosyl isothiocyanates are obtained under smooth conditions starting from the corresponding glycosyl chloride by reaction with potassium thiocyanate in anhydrous acetone at room temperature, classical conditions for the synthesis of glycopyranosyl thiocyanates. In the case of furanoses, no glycosyl thiocyanates are obtained, and the procedure leads to the 1,2-trans isothiocyanates, stereoselectively, with over 80% yield.
Registro:
Documento: |
Artículo
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Título: | Facile synthesis of glycofuranosyl isothiocyanates |
Autor: | Marino, C.; Varela, O.; De Lederkremer, R.M. |
Filiación: | CIHIDECAR, Depto. de Quím. Orgán., Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina
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Palabras clave: | Glycofuranosylisothiocyanates; Glycofuranosylthiourethanes; carbohydrate derivative; isothiocyanic acid derivative; article; carbohydrate synthesis; drug synthesis; in vitro study; priority journal; reaction analysis; stereochemistry |
Año: | 1997
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Volumen: | 304
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Número: | 3-4
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Página de inicio: | 257
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Página de fin: | 260
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DOI: |
http://dx.doi.org/10.1016/S0008-6215(97)00242-5 |
Título revista: | Carbohydrate Research
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Título revista abreviado: | Carbohydr. Res.
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ISSN: | 00086215
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CODEN: | CRBRA
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v304_n3-4_p257_Marino |
Referencias:
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Citas:
---------- APA ----------
Marino, C., Varela, O. & De Lederkremer, R.M.
(1997)
. Facile synthesis of glycofuranosyl isothiocyanates. Carbohydrate Research, 304(3-4), 257-260.
http://dx.doi.org/10.1016/S0008-6215(97)00242-5---------- CHICAGO ----------
Marino, C., Varela, O., De Lederkremer, R.M.
"Facile synthesis of glycofuranosyl isothiocyanates"
. Carbohydrate Research 304, no. 3-4
(1997) : 257-260.
http://dx.doi.org/10.1016/S0008-6215(97)00242-5---------- MLA ----------
Marino, C., Varela, O., De Lederkremer, R.M.
"Facile synthesis of glycofuranosyl isothiocyanates"
. Carbohydrate Research, vol. 304, no. 3-4, 1997, pp. 257-260.
http://dx.doi.org/10.1016/S0008-6215(97)00242-5---------- VANCOUVER ----------
Marino, C., Varela, O., De Lederkremer, R.M. Facile synthesis of glycofuranosyl isothiocyanates. Carbohydr. Res. 1997;304(3-4):257-260.
http://dx.doi.org/10.1016/S0008-6215(97)00242-5