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Abstract:

Structural analysis of two xylomannans extracted from Nothogenia fastigiata was carried out. The results are consistent with the general pattern previously reported for other xylo-mannans of the same system, α-(1 → 3)-linked D-mannans 2- and 6-sulfated and having single stubs of β-(1 → 2)-linked D-xylose, but one of the new samples contains a significant amount of 2,6-disulfated units. Both xylomannans studied are obtained as complexes with a β-D-(1 → 3)-, α-L-(1 → 4)-galactan and a β-D-(1 → 3)-, β-D-(1 → 4)-'mixed linkage' xylan co-existing in the seaweed, a fact that limits the accuracy of the data determined. The structures of the galactan and the xylan are similar to those previously informed for this seaweed. The antiviral activity against four different herpes simplex viral strains and the anticoagulant properties of all the xylo-mannans of the system are reported.

Registro:

Documento: Artículo
Título:The system of sulfated α-(1 → 3)-linked D-mannans from the red seaweed Nothogenia fastigiata: Structures, antiherpetic and anticoagulant properties
Autor:Kolender, A.A.; Pujol, C.A.; Damonte, E.B.; Matulewicz, M.C.; Cerezo, A.S.
Filiación:Depto. de Quim. Orgánica, Fac. de Ciencias Exactas y Naturales, Ciudad Universitaria, 1428 Buenos Aires, Argentina
Laboratorio de Virología, Depto. de Quim. Orgánica, Ciudad Universitaria, 1428 Buenos Aires, Argentina
Palabras clave:α-(1 → 3)-Linked mannans; α-(1 → 3)-Linked mannans, Sulfated; Antiherpetic activity; Xylomannans; Xylomannans, sulfated; anticoagulant agent; antivirus agent; galactose; mannan; mannose; natural product; unclassified drug; xylomannan; xylose; anticoagulation; antiviral activity; article; carbon nuclear magnetic resonance; chemical structure; herpes simplex; herpes simplex virus; marine environment; nonhuman; priority journal; proton nuclear magnetic resonance; seaweed; sulfation; thrombin time; virus inhibition; Anticoagulants; Antiviral Agents; Carbohydrate Conformation; Galactans; Galactose; Magnetic Resonance Spectroscopy; Mannans; Mannose; Molecular Weight; Seaweed; Simplexvirus; Sulfates; Xylans; Xylose; algae; Herpes; Nothogenia fastigiata; Simplexvirus
Año:1997
Volumen:304
Número:1
Página de inicio:53
Página de fin:60
DOI: http://dx.doi.org/10.1016/S0008-6215(97)00201-2
Título revista:Carbohydrate Research
Título revista abreviado:CARBOHYDR. RES.
ISSN:00086215
CODEN:CRBRA
CAS:Anticoagulants; Antiviral Agents; Galactans; Galactose, 26566-61-0; Mannans; Mannose, 31103-86-3; Sulfates; Xylans; Xylose
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00086215_v304_n1_p53_Kolender

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Citas:

---------- APA ----------
Kolender, A.A., Pujol, C.A., Damonte, E.B., Matulewicz, M.C. & Cerezo, A.S. (1997) . The system of sulfated α-(1 → 3)-linked D-mannans from the red seaweed Nothogenia fastigiata: Structures, antiherpetic and anticoagulant properties. Carbohydrate Research, 304(1), 53-60.
http://dx.doi.org/10.1016/S0008-6215(97)00201-2
---------- CHICAGO ----------
Kolender, A.A., Pujol, C.A., Damonte, E.B., Matulewicz, M.C., Cerezo, A.S. "The system of sulfated α-(1 → 3)-linked D-mannans from the red seaweed Nothogenia fastigiata: Structures, antiherpetic and anticoagulant properties" . Carbohydrate Research 304, no. 1 (1997) : 53-60.
http://dx.doi.org/10.1016/S0008-6215(97)00201-2
---------- MLA ----------
Kolender, A.A., Pujol, C.A., Damonte, E.B., Matulewicz, M.C., Cerezo, A.S. "The system of sulfated α-(1 → 3)-linked D-mannans from the red seaweed Nothogenia fastigiata: Structures, antiherpetic and anticoagulant properties" . Carbohydrate Research, vol. 304, no. 1, 1997, pp. 53-60.
http://dx.doi.org/10.1016/S0008-6215(97)00201-2
---------- VANCOUVER ----------
Kolender, A.A., Pujol, C.A., Damonte, E.B., Matulewicz, M.C., Cerezo, A.S. The system of sulfated α-(1 → 3)-linked D-mannans from the red seaweed Nothogenia fastigiata: Structures, antiherpetic and anticoagulant properties. CARBOHYDR. RES. 1997;304(1):53-60.
http://dx.doi.org/10.1016/S0008-6215(97)00201-2