Abstract:
1. Chick embryos of 7, 9, 11, 12, 13, 14, 15, 17 and 19 d of embryonic development were examined to determine the activities of 5-aminolevulinic dehydratase (ALA-D, EC 4.2.1.24) and porphobilinogen deaminase (PBG-D, EC 4.3.1.8). 2. Liver and yolk sac membrane ALA-D specific activities showed a maximum between 12 and 13 d of embryonic development, yolk sac membrane PBG-ase activity a maximum at 9 d and at 7 d in liver. Total activities of ALA-D and PBG-D were not constant during the course of embryonic development but probably related to the changes of intensity of haem synthesis. 3. ALA-D and PBG-ase activities were higher in yolk sac membrane than in liver, showing the importance of the yolk sac membrane as erythropoietic tissue. PBG-D catalysed the rate-limiting reaction of the cytosolic steps in the biosynthetic pathway in both tissues.
Registro:
Documento: |
Artículo
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Título: | Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos |
Autor: | Pauza, N.L.; Sopena De Kracoff, Y.E.; Ferramola De Sancovich, A.M.; Sancovich, H.A. |
Filiación: | Laboratorio de Porfirinas, Depto. de Quim. Biológica, Pabellón II, 1428, Capital Federal, Buenos Aires, Argentina Navarro 4557, (1419), Buenos Aires, Argentina
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Palabras clave: | porphobilinogen deaminase; porphobilinogen synthase; age; animal; article; chick embryo; enzymology; growth, development and aging; liver; metabolism; prenatal development; spectrophotometry; yolk sac; Age Factors; Animals; Chick Embryo; Hydroxymethylbilane Synthase; Liver; Porphobilinogen Synthase; Spectrophotometry; Yolk Sac |
Año: | 2002
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Volumen: | 43
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Número: | 2
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Página de inicio: | 196
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Página de fin: | 203
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DOI: |
http://dx.doi.org/10.1080/00071660120121391 |
Título revista: | British Poultry Science
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Título revista abreviado: | Brit. Poult. Sci.
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ISSN: | 00071668
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CAS: | Hydroxymethylbilane Synthase, EC 2.5.1.61; Porphobilinogen Synthase, EC 4.2.1.24
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00071668_v43_n2_p196_Pauza |
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Citas:
---------- APA ----------
Pauza, N.L., Sopena De Kracoff, Y.E., Ferramola De Sancovich, A.M. & Sancovich, H.A.
(2002)
. Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos. British Poultry Science, 43(2), 196-203.
http://dx.doi.org/10.1080/00071660120121391---------- CHICAGO ----------
Pauza, N.L., Sopena De Kracoff, Y.E., Ferramola De Sancovich, A.M., Sancovich, H.A.
"Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos"
. British Poultry Science 43, no. 2
(2002) : 196-203.
http://dx.doi.org/10.1080/00071660120121391---------- MLA ----------
Pauza, N.L., Sopena De Kracoff, Y.E., Ferramola De Sancovich, A.M., Sancovich, H.A.
"Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos"
. British Poultry Science, vol. 43, no. 2, 2002, pp. 196-203.
http://dx.doi.org/10.1080/00071660120121391---------- VANCOUVER ----------
Pauza, N.L., Sopena De Kracoff, Y.E., Ferramola De Sancovich, A.M., Sancovich, H.A. Ontogeny of 5-aminolevulinic dehydratase and porphobilinogen deaminase activities in the yolk sac membrane and liver of chick embryos. Brit. Poult. Sci. 2002;43(2):196-203.
http://dx.doi.org/10.1080/00071660120121391