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Abstract:

The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a significant LH release was found at day 22; Px rats showed a steroid-induced LH depression only at day 16, a positive feedback being detectable at day 20, 2 days earlier than in sham Px or intact rats. Daily injections of 10-50 μg melatonin to intact rats disrupted the LH negative feedback response at day 20, and diminished steroid-induced LH release at day 24. © 1982.

Registro:

Documento: Artículo
Título:Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
Autor:Faigón, M.R.; Cardinali, D.P.; Moguilevsky, J.A.
Filiación:Centro de Investigaciones Médicas 'Alberto Einstein' y de Pricipios Naturales, Buenos Aires, Argentina
Centro de Estudios Farmacológicos y de Principios Naturales, Buenos Aires, Argentina
Palabras clave:luteinizing hormone release; melatonin; pineal gland; puberty; estradiol; gonadorelin; luteinizing hormone; melatonin; progesterone; animal experiment; central nervous system; endocrine system; feedback system; pineal body; pinealectomy; puberty; rat; subcutaneous drug administration; Animal; Estradiol; Feedback; Female; Luteinizing Hormone; Pineal Gland; Progesterone; Rats; Rats, Inbred Strains; Sex Maturation; Support, Non-U.S. Gov't
Año:1982
Volumen:241
Número:2
Página de inicio:366
Página de fin:369
DOI: http://dx.doi.org/10.1016/0006-8993(82)91080-0
Título revista:Brain Research
Título revista abreviado:Brain Res.
ISSN:00068993
CODEN:BRREA
CAS:estradiol, 50-28-2; gonadorelin, 33515-09-2, 9034-40-6; luteinizing hormone, 39341-83-8, 9002-67-9; melatonin, 73-31-4; progesterone, 57-83-0; Estradiol, 50-28-2; Luteinizing Hormone, 9002-67-9; Progesterone, 57-83-0
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v241_n2_p366_Faigon

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Citas:

---------- APA ----------
Faigón, M.R., Cardinali, D.P. & Moguilevsky, J.A. (1982) . Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats. Brain Research, 241(2), 366-369.
http://dx.doi.org/10.1016/0006-8993(82)91080-0
---------- CHICAGO ----------
Faigón, M.R., Cardinali, D.P., Moguilevsky, J.A. "Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats" . Brain Research 241, no. 2 (1982) : 366-369.
http://dx.doi.org/10.1016/0006-8993(82)91080-0
---------- MLA ----------
Faigón, M.R., Cardinali, D.P., Moguilevsky, J.A. "Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats" . Brain Research, vol. 241, no. 2, 1982, pp. 366-369.
http://dx.doi.org/10.1016/0006-8993(82)91080-0
---------- VANCOUVER ----------
Faigón, M.R., Cardinali, D.P., Moguilevsky, J.A. Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats. Brain Res. 1982;241(2):366-369.
http://dx.doi.org/10.1016/0006-8993(82)91080-0