Abstract:
Angiotensin converting enzyme was detectable in rat pineal gland and exhibited a circadian rhythm in activity with maximum at the end of the light phase of daily photoperiod. Superior cervical ganglionectomy (SCGx) or exposure to light for 6 days increased enzyme activity and obliterated morning-evening differences, whereas injection of the β-agonist isoproterenol depressed the high values observed in SCGx animals. These results indicate that angiotensin converting enzyme in the pineal gland is under negative control by the norepinephrine released from pineal sympathetic nerves. © 1982.
Registro:
Documento: |
Artículo
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Título: | Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme |
Autor: | Nahmod, V.E.; Balda, M.S.; Pirola, C.J.; Finkielman, S.; Gejman, P.V.; Cardinali, D.P. |
Filiación: | Laboratorio de Sustancias Vasoactivas, Instituto de Investigaciones Médicas de Medicina, U.B.A., Argentina Centro de Estudios Farmacológicos y de Principios Naturales, Buenos Aires, Argentina
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Palabras clave: | angiotensin; angiotensin converting enzyme; Captopril; circadian rhythms; norepinephrine; pineal gland; superior cervical ganglia; captopril; dipeptidyl carboxypeptidase; isoprenaline; noradrenalin; sq 14,225; unclassified drug; animal experiment; autonomic nervous system; circadian rhythm; endocrine system; pineal body; rat; superior cervical ganglion; Animals; Circadian Rhythm; Ganglia, Sympathetic; Isoproterenol; Light; Male; Norepinephrine; Peptidyl-Dipeptidase A; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Spinal Cord |
Año: | 1982
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Volumen: | 236
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Número: | 1
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Página de inicio: | 216
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Página de fin: | 220
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DOI: |
http://dx.doi.org/10.1016/0006-8993(82)90049-X |
Título revista: | Brain Research
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Título revista abreviado: | Brain Res.
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ISSN: | 00068993
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CODEN: | BRREA
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CAS: | captopril, 62571-86-2; dipeptidyl carboxypeptidase, 9015-82-1; isoprenaline, 299-95-6, 51-30-9, 6700-39-6, 7683-59-2; noradrenalin, 1407-84-7, 51-41-2; Isoproterenol, 7683-59-2; Norepinephrine, 51-41-2; Peptidyl-Dipeptidase A, 3.4.15.1; Receptors, Adrenergic, beta
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068993_v236_n1_p216_Nahmod |
Referencias:
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Citas:
---------- APA ----------
Nahmod, V.E., Balda, M.S., Pirola, C.J., Finkielman, S., Gejman, P.V. & Cardinali, D.P.
(1982)
. Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme. Brain Research, 236(1), 216-220.
http://dx.doi.org/10.1016/0006-8993(82)90049-X---------- CHICAGO ----------
Nahmod, V.E., Balda, M.S., Pirola, C.J., Finkielman, S., Gejman, P.V., Cardinali, D.P.
"Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme"
. Brain Research 236, no. 1
(1982) : 216-220.
http://dx.doi.org/10.1016/0006-8993(82)90049-X---------- MLA ----------
Nahmod, V.E., Balda, M.S., Pirola, C.J., Finkielman, S., Gejman, P.V., Cardinali, D.P.
"Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme"
. Brain Research, vol. 236, no. 1, 1982, pp. 216-220.
http://dx.doi.org/10.1016/0006-8993(82)90049-X---------- VANCOUVER ----------
Nahmod, V.E., Balda, M.S., Pirola, C.J., Finkielman, S., Gejman, P.V., Cardinali, D.P. Circadian rhythm and neural regulation of rat pineal angiotensin converting enzyme. Brain Res. 1982;236(1):216-220.
http://dx.doi.org/10.1016/0006-8993(82)90049-X