Artículo

Sitt, J.D.; King, J.-R.; El Karoui, I.; Rohaut, B.; Faugeras, F.; Gramfort, A.; Cohen, L.; Sigman, M.; Dehaene, S.; Naccache, L. "Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state" (2014) Brain. 137(8):2258-2270
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Abstract:

In recent years, numerous electrophysiological signatures of consciousness have been proposed. Here, we perform a systematic analysis of these electroencephalography markers by quantifying their efficiency in differentiating patients in a vegetative state from those in a minimally conscious or conscious state. Capitalizing on a review of previous experiments and current theories, we identify a series of measures that can be organized into four dimensions: (i) event-related potentials versus ongoing electroencephalography activity; (ii) local dynamics versus inter-electrode information exchange; (iii) spectral patterns versus information complexity; and (iv) average versus fluctuations over the recording session. We analysed a large set of 181 high-density electroencephalography recordings acquired in a 30 minutes protocol. We show that low-frequency power, electroencephalography complexity, and information exchange constitute the most reliable signatures of the conscious state. When combined, these measures synergize to allow an automatic classification of patients' state of consciousness. © 2014 The Author (2014).

Registro:

Documento: Artículo
Título:Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state
Autor:Sitt, J.D.; King, J.-R.; El Karoui, I.; Rohaut, B.; Faugeras, F.; Gramfort, A.; Cohen, L.; Sigman, M.; Dehaene, S.; Naccache, L.
Filiación:Cognitive Neuroimaging Unit, Institut National de la Santé et de la Recherche Médicale, U992, F-91191 Gif/Yvette, France
NeuroSpin Centre, Institute of BioImaging Commissariat à l'Energie Atomique, F-91191 Gif/Yvette, France
Inserm U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Institut du Cerveau et de la Moelle épinière, ICM, F-75013, Paris, France
AP-HP, Groupe hospitalier Pitié-Salpêtrière, Department of Neurology, Intensive Care Unit, Paris, France
AP-HP, Groupe hospitalier Pitié-Salpêtrière, Department of Neurophysiology, Paris, France
Institut Mines-Télécom, Télécom ParisTech, CNRS LTCI, France
Integrative Neuroscience Laboratory, Physics Department, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Universidad Torcuato Di Tella, Almirante Juan Saenz Valiente 1010, C1428BIJ Buenos Aires, Argentina
Université Paris 11, Orsay, France
Collège de France, F-75005 Paris, France
Palabras clave:consciousness; EEG; minimally conscious state; unresponsive wakefulness syndrome; vegetative state; alpha rhythm; article; auditory stimulation; consciousness; electrode; electroencephalogram; electroencephalography; human; minimally conscious state; neurologic examination; persistent vegetative state; priority journal; systematic review; theta rhythm; wakefulness; consciousness; EEG; minimally conscious state; unresponsive wakefulness syndrome; vegetative state; Adolescent; Adult; Aged; Aged, 80 and over; Biological Markers; Brain; Brain Mapping; Clinical Protocols; Consciousness Disorders; Electroencephalography; Evoked Potentials; Female; Humans; Male; Middle Aged; Persistent Vegetative State; Trauma Severity Indices; Young Adult
Año:2014
Volumen:137
Número:8
Página de inicio:2258
Página de fin:2270
DOI: http://dx.doi.org/10.1093/brain/awu141
Título revista:Brain
Título revista abreviado:Brain
ISSN:00068950
CODEN:BRAIA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00068950_v137_n8_p2258_Sitt

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Citas:

---------- APA ----------
Sitt, J.D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., Cohen, L.,..., Naccache, L. (2014) . Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state. Brain, 137(8), 2258-2270.
http://dx.doi.org/10.1093/brain/awu141
---------- CHICAGO ----------
Sitt, J.D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., et al. "Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state" . Brain 137, no. 8 (2014) : 2258-2270.
http://dx.doi.org/10.1093/brain/awu141
---------- MLA ----------
Sitt, J.D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., et al. "Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state" . Brain, vol. 137, no. 8, 2014, pp. 2258-2270.
http://dx.doi.org/10.1093/brain/awu141
---------- VANCOUVER ----------
Sitt, J.D., King, J.-R., El Karoui, I., Rohaut, B., Faugeras, F., Gramfort, A., et al. Large scale screening of neural signatures of consciousness in patients in a vegetative or minimally conscious state. Brain. 2014;137(8):2258-2270.
http://dx.doi.org/10.1093/brain/awu141