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Referencias:

• Farkkila, A., Pihlajoki, M., Tauriala, H., Butzow, R., Leminen, A., Unkila-Kallio, L., Heikinheimo, M., Anttonen, M., Serum vascular endothelial growth factor A (VEGF) is elevated in patients with ovarian granulosa cell tumor (GCT), and VEGF inhibition by bevacizumab induces apoptosis in GCT in vitro (2011) J Clin Endocrinol Metab, 96, pp. E1973-E1981
• Shah, S.P., Kobel, M., Senz, J., Morin, R.D., Clarke, B.A., Wiegand, K.C., Leung, G., Giuliany, R., Mutation of FOXL2 in granulosa-cell tumors of the ovary (2009) N Engl J Med, 360, pp. 2719-2729
• Kobel, M., Gilks, C.B., Huntsman, D.G., Adult-type granulosa cell tumors and FOXL2 mutation (2009) Cancer Res, 69, pp. 9160-9162
• Kalfa, N., Veitia, R.A., Benayoun, B.A., Boizet-Bonhoure, B., Sultan, C., The new molecular biology of granulosa cell tumors of the ovary (2009) Genome Med, 1, pp. 811-814
• Jamieson, S., Butzow, R., Andersson, N., Alexiadis, M., Unkila-Kallio, L., Heikinheimo, M., Fuller, P.J., Anttonen, M., The FOXL2 C134W mutation is characteristic of adult granulosa cell tumors of the ovary (2010) Mod Pathol, 23, pp. 1477-1485
• Geiersbach, K.B., Jarboe, E.A., Jahromi, M.S., Baker, C.L., Paxton, C.N., Tripp, S.R., Schiffman, J.D., FOXL2 mutation and large-scale genomic imbalances in adult granulosa cell tumors of the ovary (2011) Cancer Genet, 204, pp. 596-602
• Caburet, S., Georges, A., L'Hote, D., Todeschini, A.L., Benayoun, B.A., Veitia, R.A., The transcription factor FOXL2: at the crossroads of ovarian physiology and pathology (2012) Mol Cell Endocrinol, 356, pp. 55-64
• Kim, T., Sung, C.O., Song, S.Y., Bae, D.S., Choi, Y.L., FOXL2 mutation in granulosa-cell tumours of the ovary (2010) Histopathology, 56, pp. 408-410
• Kim, M.S., Hur, S.Y., Yoo, N.J., Lee, S.H., Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers (2010) J Pathol, 221, pp. 147-152
• Al Agha, O.M., Huwait, H.F., Chow, C., Yang, W., Senz, J., Kalloger, S.E., Huntsman, D.G., Gilks, C.B., FOXL2 is a sensitive and specific marker for sex cord-stromal tumors of the ovary (2011) Am J Surg Pathol, 35, pp. 484-494
• Hes, O., Vanecek, T., Petersson, F., Grossmann, P., Hora, M., Perez Montiel, D.M., Steiner, P., Michal, M., Mutational analysis (c.402C.G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors (2011) Appl Immunohistochem Mol Morphol, 19, pp. 347-351
• Kopan, R., Ilagan, M.X., The canonical Notch signaling pathway: unfolding the activation mechanism (2009) Cell, 137, pp. 216-233
• Ranganathan, P., Weaver, K.L., Capobianco, A.J., Notch signalling in solid tumours: a little bit of everything but not all the time (2011) Nat Rev Cancer, 11, pp. 338-351
• Takeshita, K., Satoh, M., Ii, M., Silver, M., Limbourg, F.P., Mukai, Y., Rikitake, Y., Liao, J.K., Critical role of endothelial Notch1 signaling in postnatal angiogenesis (2007) Circ Res, 100, pp. 70-78
• Reedijk, M., Odorcic, S., Chang, L., Zhang, H., Miller, N., McCready, D.R., Lockwood, G., Egan, S.E., High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival (2005) Cancer Res, 65, pp. 8530-8537
• Rizzo, P., Miao, H., D'Souza, G., Osipo, C., Song, L.L., Yun, J., Zhao, H., Yao, K., Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches (2008) Cancer Res, 68, pp. 5226-5235
• Santagata, S., Demichelis, F., Riva, A., Varambally, S., Hofer, M.D., Kutok, J.L., Kim, R., Aster, J.C., JAGGED1 expression is associated with prostate cancer metastasis and recurrence (2004) Cancer Res, 64, pp. 6854-6857
• Bell Da, T.E., Integrated genomic analyses of ovarian carcinoma (2011) Nature, 474, pp. 609-615
• Steg, A.D., Katre, A.A., Goodman, B., Han, H.D., Nick, A.M., Stone, R.L., Coleman, R.L., Landen, C.N., Targeting the notch ligand JAGGED1 in both tumor cells and stroma in ovarian cancer (2011) Clin Cancer Res, 17, pp. 5674-5685
• Hu, W., Lu, C., Dong, H.H., Huang, J., Shen, D.Y., Stone, R.L., Nick, A.M., Roh, J.W., Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer (2011) Cancer Res, 71, pp. 6030-6039
• Franke, T.F., Hornik, C.P., Segev, L., Shostak, G.A., Sugimoto, C., PI3K/Akt and apoptosis: size matters (2003) Oncogene, 22, pp. 8983-8998
• Cantley, L.C., Neel, B.G., New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/ AKT pathway (1999) Proc Natl Acad Sci, 96, pp. 4240-4245. , USA
• Yang, X., Fraser, M., Moll, U.M., Basak, A., Tsang, B.K., Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspasedependent mitochondrial death pathway (2006) Cancer Res, 66, pp. 3126-3136
• Altomare, D.A., Wang, H.Q., Skele, K.L., De Rienzo, A., Klein-Szanto, A.J., Godwin, A.K., Testa, J.R., AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth (2004) Oncogene, 23, pp. 5853-5857
• Woenckhaus, J., Steger, K., Sturm, K., Munstedt, K., Franke, F.E., Fenic, I., Prognostic value of PIK3CA and phosphorylated AKT expression in ovarian cancer (2007) Virchows Arch, 450, pp. 387-395
• Kolasa, I.K., Rembiszewska, A., Felisiak, A., Ziolkowska-Seta, I., Murawska, M., Moes, J., Timorek, A., Kupryjanczyk, J., PIK3CA amplification associates with resistance to chemotherapy in ovarian cancer patients (2009) Cancer Biol Ther, 8, pp. 21-26
• Meurette, O., Stylianou, S., Rock, R., Collu, G.M., Gilmore, A.P., Brennan, K., Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells (2009) Cancer Res, 69, pp. 5015-5022
• Wang, Z., Li, Y., Ahmad, A., Banerjee, S., Azmi, A.S., Kong, D., Wojewoda, C., Sarkar, F.H., Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells (2011) J Cell Biochem, 112, pp. 78-88
• Nishi, Y., Yanase, T., Mu, Y., Oba, K., Ichino, I., Saito, M., Nomura, M., Kashimura, Y., Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor (2001) Endocrinology, 142, pp. 437-445
• Imai, M., Muraki, M., Takamatsu, K., Saito, H., Seiki, M., Takahashi, Y., Spontaneous transformation of human granulosa cell tumours into an aggressive phenotype: a metastasis model cell line (2008) BMC Cancer, 8, p. 319
• Dain, L.B., Bley, M.A., Baranao, J.L., Tesone, M., Evidence for the production of a growth-inhibitory factor by human granulosa-luteal cells (1993) Mol Reprod Dev, 36, pp. 159-163
• Dain, L., Guerrero, H., Polak, D.F., Tesone, M., Regulation of the steroidogenic response of cultured human granulosa cells: effects of serum and 25- hydroxycholesterol (1995) Fertil Steril, 64, pp. 335-339
• Wang, Z., Li, Y., Banerjee, S., Kong, D., Ahmad, A., Nogueira, V., Hay, N., Sarkar, F.H., Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-kappaB signaling pathways (2010) J Cell Biochem, 109, pp. 726-736
• Fan, R.H., Li, J., Wu, N., Chen, P.S., Late SV40 factor: a key mediator of Notch signaling in human hepatocarcinogenesis (2011) World J Gastroenterol, 17, pp. 3420-3430
• Bley, M.A., Saragueta, P.E., Baranao, J.L., Concerted stimulation of rat granulosa cell deoxyribonucleic acid synthesis by sex steroids and folliclestimulating hormone (1997) J Steroid Biochem Mol Biol, 62, pp. 11-19
• Rosen, A., Casciola-Rosen, L., Macromolecular substrates for the ICE-like proteases during apoptosis (1997) J Cell Biochem, 64, pp. 50-54
• Choi, J.H., Park, J.T., Davidson, B., Morin, P.J., Shih, I., Wang, T.L., Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion (2008) Cancer Res, 68, pp. 5716-5723
• Iwase, A., Goto, M., Harata, T., Takigawa, S., Nakahara, T., Suzuki, K., Manabe, S., Kikkawa, F., Insulin attenuates the insulin-like growth factor-I (IGF-I)- Akt pathway, not IGF-I-extracellularly regulated kinase pathway, in luteinized granulosa cells with an increase in PTEN (2009) J Clin Endocrinol Metab, 94, pp. 2184-2191
• Hernandez, F., Peluffo, M.C., Stouffer, R.L., Irusta, G., Tesone, M., Role of the DLL4-NOTCH system in PGF2alpha-induced luteolysis in the pregnant rat (2011) Biol Reprod, 84, pp. 859-865
• Mori, M., Miyamoto, T., Yakushiji, H., Ohno, S., Miyake, Y., Sakaguchi, T., Hattori, M., Ohno, E., Effects of N-[N-(3, 5-difluorophenacetyl-L:-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells (2012) Hum Cell, 25 (1), pp. 9-15
• Guo, S., Gonzalez-Perez, R.R., Notch, IL-1 and leptin crosstalk outcome (NILCO) is critical for leptin-induced proliferation, migration and VEGF/ VEGFR-2 expression in breast cancer (2011) PLoS One, 6, pp. e21467
• Sjolund, J., Johansson, M., Manna, S., Norin, C., Pietras, A., Beckman, S., Nilsson, E., Axelson, H., Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo (2008) J Clin Invest, 118, pp. 217-228
• Eliasz, S., Liang, S., Chen, Y., De Marco, M.A., Machek, O., Skucha, S., Miele, L., Bocchetta, M., Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway (2010) Oncogene, 29, pp. 2488-2498
• Miele, L., Golde, T., Osborne, B., Notch signaling in cancer (2006) Curr Mol Med, 6, pp. 905-918
• Clinton, G.M., Hua, W., Estrogen action in human ovarian cancer (1997) Crit Rev Oncol Hematol, 25, pp. 1-9
• Emons, G., Kavanagh, J.J., Hormonal interactions in ovarian cancer (1999) Hematol Oncol Clin North Am, 13, pp. 145-161. , ix
• Sai, T., Matsuda, F., Goto, Y., Maeda, A., Sugimoto, M., Gao, H.M., Kabir, A.K., Manabe, N., Effect of RNA interference of BID and BAX mRNAs on apoptosis in granulosa cell-derived KGN cells (2012) J Reprod Dev, 58, pp. 112-116
• Schuyer, M., van der Burg, M.E., Henzen-Logmans, S.C., Fieret, J.H., Klijn, J.G., Look, M.P., Foekens, J.A., Berns, E.M., Reduced expression of BAX is associated with poor prognosis in patients with epithelial ovarian cancer: a multifactorial analysis of TP53, p21, BAX and BCL-2 (2001) Br J Cancer, 85, pp. 1359-1367
• Baekelandt, M., Holm, R., Nesland, J.M., Trope, C.G., Kristensen, G.B., Expression of apoptosis-related proteins is an independent determinant of patient prognosis in advanced ovarian cancer (2000) J Clin Oncol, 18, pp. 3775-3781
• Wang, J., Zhou, J.Y., Zhang, L., Wu, G.S., Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells (2009) Cell Cycle, 8, pp. 3191-3198
• Placzek, W.J., Wei, J., Kitada, S., Zhai, D., Reed, J.C., Pellecchia, M., A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy (2010) Cell Death Dis, 1, pp. e40
• Anderson, N.S., Turner, L., Livingston, S., Chen, R., Nicosia, S.V., Kruk, P.A., Bcl-2 expression is altered with ovarian tumor progression: an immunohistochemical evaluation (2009) J Ovarian Res, 2, p. 16
• Kyronlahti, A., Ramo, M., Tamminen, M., Unkila-Kallio, L., Butzow, R., Leminen, A., Nemer, M., Anttonen, M., GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors (2008) Endocrinology, 149, pp. 5635-5642
• Kyronlahti, A., Kauppinen, M., Lind, E., Unkila-Kallio, L., Butzow, R., Klefstrom, J., Wilson, D.B., Heikinheimo, M., GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis (2010) Endocr Relat Cancer, 17, pp. 709-717
• Quirk, S.M., Cowan, R.G., Joshi, S.G., Henrikson, K.P., Fas antigen-mediated apoptosis in human granulosa/luteal cells (1995) Biol Reprod, 52, pp. 279-287
• Hakuno, N., Koji, T., Yano, T., Kobayashi, N., Tsutsumi, O., Taketani, Y., Nakane, P.K., Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia (1996) Endocrinology, 137, pp. 1938-1948
• Shayesteh, L., Lu, Y., Kuo, W.L., Baldocchi, R., Godfrey, T., Collins, C., Pinkel, D., Gray, J.W., PIK3CA is implicated as an oncogene in ovarian cancer (1999) Nat Genet, 21, pp. 99-102
• Huang, J., Zhang, L., Greshock, J., Colligon, T.A., Wang, Y., Ward, R., Katsaros, D., Nathanson, K.L., Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome (2011) Genes Chromosomes Cancer, 50, pp. 606-618
• Nair, P., Somasundaram, K., Krishna, S., Activated Notch1 inhibits p53- induced apoptosis and sustains transformation by human papillomavirus type 16 E6 and E7 oncogenes through a PI3K-PKB/Akt-dependent pathway (2003) J Virol, 77, pp. 7106-7112
• Sade, H., Krishna, S., Sarin, A., The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells (2004) J Biol Chem, 279, pp. 2937-2944
• Palomero, T., Sulis, M.L., Cortina, M., Real, P.J., Barnes, K., Ciofani, M., Caparros, E., Agarwal, A.M., Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia (2007) Nat Med, 13, pp. 1203-1210
• Lague, M.N., Paquet, M., Fan, H.Y., Kaartinen, M.J., Chu, S., Jamin, S.P., Behringer, R.R., Richards, J.S., Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression (2008) Carcinogenesis, 29, pp. 2062-2072

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